Bissan Al-Lazikani

发表

Public resources for chemical probes: the journey so far and the road ahead.

Albert A Antolin, Paul Workman, Bissan Al-Lazikani, 2019, Future medicinal chemistry.

Chemogenomic assessment of SAR data from learned journals

Bissan Al-Lazikani, R Cox, Awe Chan, 2005 .

Minimum information about a bioactive entity (MIABE)

Peter Murray-Rust, John P. Overington, Henning Hermjakob, 2011, Nature Reviews Drug Discovery.

Abstract A024: Probe Miner: objective, quantitative, data-driven assessment of chemical probes for target validation

Paul Workman, Bissan Al-Lazikani, Angeliki Komianou, 2018 .

Chapter 36. The Molecular Basis of Predicting Druggability

John P. Overington, Anna Gaulton, Bissan Al-Lazikani, 2008 .

Distinctive Behaviors of Druggable Proteins in Cellular Networks

Paul Workman, Bissan Al-Lazikani, Amanda C. Schierz, 2015, PLoS Comput. Biol..

canSAR: update to the cancer translational research and drug discovery knowledgebase

Paul Workman, Bissan Al-Lazikani, Eloy D. Villasclaras-Fernández, 2018, Nucleic Acids Res..

canSAR: an integrated cancer public translational research and drug discovery resource

Bissan Al-Lazikani, Mark D. Halling-Brown, Krishna C. Bulusu, 2011, Nucleic Acids Res..

SiGNet: A signaling network data simulator to enable signaling network inference

Paul Workman, Bissan Al-Lazikani, Costas Mitsopoulos, 2017, PloS one.

ChEMBL: a large-scale bioactivity database for drug discovery

John P. Overington, Anne Hersey, Anna Gaulton, 2011, Nucleic Acids Res..

Protein structure prediction.

Veronica Morea, Bissan Al-Lazikani, Emma E Hill, 2008, Methods in molecular biology.

Transforming cancer drug discovery with Big Data and AI

Albert A Antolin, Paul Workman, Bissan Al-Lazikani, 2019, Expert opinion on drug discovery.

SCOPEC: a database of protein catalytic domains

Janet M. Thornton, Richard A. George, Bissan Al-Lazikani, 2004, ISMB/ECCB.

Abstract CN01-02: canSAR: An integrated cancer drug discovery informatics platform allowing systematic target evaluation.

Bissan Al-Lazikani, Mark Halling-Brown, Krishna C. Bulusu, 2011 .

Drug discovery in advanced prostate cancer: translating biology into therapy

Paul Workman, Bissan Al-Lazikani, Timothy A. Yap, 2016, Nature Reviews Drug Discovery.

The complement of enzymatic sets in different species.

Janet M Thornton, Shiri Freilich, Bissan Al-Lazikani, 2005, Journal of molecular biology.

Unpicking the combination lock for mutant BRAF and RAS melanomas.

Paul Workman, Bissan Al-Lazikani, B. Al-Lazikani, 2013, Cancer discovery.

Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases

Paul Workman, Bissan Al-Lazikani, Sibylle Mittnacht, 2019, bioRxiv.

Personalized medicine: patient-predictive panel power.

Paul Workman, Bissan Al-Lazikani, B. Al-Lazikani, 2012, Cancer cell.

Ligand efficiency indices for an effective mapping of chemico-biological space: the concept of an atlas-like representation.

John P. Overington, Bissan Al-Lazikani, John Overington, 2010, Drug discovery today.

canSAR: update to the cancer translational research and drug discovery knowledgebase

Albert A Antolin, Paul Workman, Bissan Al-Lazikani, 2020, Nucleic Acids Res..

The genome of the blood fluke Schistosoma mansoni

John P. Overington, Adhemar Zerlotini, Anna V. Protasio, 2009, Nature.

Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

Bissan Al-Lazikani, Sandra J. Strauss, Wenbin Wei, 2016, Cell reports.

Polypharmacology in Precision Oncology: Current Applications and Future  Prospects

Jordi Mestres, Paul Workman, Bissan Al-Lazikani, 2016, Current pharmaceutical design.

Canonical structures for the hypervariable regions of T cell αβ receptors 1 1 Edited by J. M. Thornton

Cyrus Chothia, Arthur M. Lesk, Bissan Al-Lazikani, 2000 .

Sequence, structure and energetic determinants of phosphopeptide selectivity of SH2 domains.

Bissan Al-Lazikani, Barry Honig, B. Al-Lazikani, 2003, Journal of molecular biology.

PDBe-KB: a community-driven resource for structural and functional annotations

Alfonso Valencia, Karel Berka, Jaroslav Koča, 2019, Nucleic Acids Res..

Objective, Quantitative, Data-Driven Assessment of Chemical Probes

Ian Collins, Paul Workman, Bissan Al-Lazikani, 2017, bioRxiv.

Genome-based cancer therapeutics: targets, kinase drug resistance and future strategies for precision oncology.

Paul Workman, Bissan Al-Lazikani, B. Al-Lazikani, 2013, Current opinion in pharmacology.

Collation and data-mining of literature bioactivity data for drug discovery.

John P. Overington, Anne Hersey, Anna Gaulton, 2011, Biochemical Society transactions.