Nathanael S. Gray

发表

BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells

Bandana Sharma, Eugenio Marco, Guo-Cheng Yuan, 2019, Nature.

Chapter 3:Immediate and Selective Control of Protein Abundance Using the dTAG System

Behnam Nabet, Nathanael S. Gray, 2020 .

CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer

Bandana Sharma, Eugenio Marco, Guo-Cheng Yuan, 2014, Cell.

Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

John R. Engen, Kwok-Kin Wong, Liang Chen, 2009, Nature.

Chaperones as thermodynamic sensors of drug–target interactions reveal kinase inhibitor specificities in living cells

Sandro Santagata, Susan Lindquist, Luke Whitesell, 2013, Nature Biotechnology.

Kang Starvation and Rapamycin mTORC 1 Phosphorylation Sites Encode Their Sensitivity to

Michael B. Yaffe, David M. Sabatini, Benjamin E. Turk, 2013 .

A Structure-Based Library Approach to Kinase Inhibitors

Peter G. Schultz, Thea Norman, Nathanael S. Gray, 1996 .

Inhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction

Maurizio Sanguinetti, Gerhard Wagner, Haribabu Arthanari, 2016, Nature.

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

Sridhar Ramaswamy, Taebo Sim, Richard A Young, 2014, Nature.

The Immunological Evolution of Catalysis

Peter G. Schultz, Raymond C. Stevens, Nathanael S. Gray, 1996, Science.

In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

Peter G. Schultz, Yingyao Zhou, Elizabeth A. Winzeler, 2008, Proceedings of the National Academy of Sciences.

EML4-ALK Fusion Gene and Efficacy of an ALK Kinase Inhibitor in Lung Cancer

Derek Y. Chiang, Matthew Meyerson, William G. Richards, 2008, Clinical Cancer Research.

Conformational disturbance in Abl kinase upon mutation and deregulation

John R. Engen, Nathanael S. Gray, N. Gray, 2009, Proceedings of the National Academy of Sciences.

Synthetic small molecules that control stem cell fate

Peter G. Schultz, Eric C. Peters, Nathanael S. Gray, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK

Peter G. Schultz, Yi Liu, Jiqing Jiang, 2007, Proceedings of the National Academy of Sciences.

Combinatorial synthesis of 2,9-substituted purines

Peter G. Schultz, Nathanael S. Gray, P. Schultz, 1997 .

Structural Mechanisms Determining Inhibition of the Collagen Receptor DDR1 by Selective and Multi-Targeted Type II Kinase Inhibitors

Kiki Chu, Peter Canning, Nathanael S. Gray, 2014, Journal of molecular biology.

A chemical switch for inhibitor-sensitive alleles of any protein kinase

Peter G. Schultz, Joe Z. Tsien, Kevan M. Shokat, 2000, Nature.

Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages

Patrick G. A. Pedrioli, Nathanael S. Gray, P. Cohen, 2012, Proceedings of the National Academy of Sciences.

Allosteric Interactions between the Myristate- and ATP-Site of the Abl Kinase

John R. Engen, Nathanael S. Gray, N. Gray, 2011, PloS one.

Identification of Existing Drugs That Effectively Target NTRK1 and ROS1 Rearrangements in Lung Cancer

Taebo Sim, Takayuki Kosaka, Nathanael S. Gray, 2016, Clinical Cancer Research.

Plasticity in binding confers selectivity in ligand induced protein degradation

James E. Bradner, Eric S. Fischer, Nathanael S. Gray, 2018, Nature Chemical Biology.

Activating mutations in ALK provide a therapeutic target in neuroblastoma

D. Gary Gilliland, Stefan Fröhling, Wendy B. London, 2008, Nature.

Small Molecule Kinase Inhibitors Provide Insight into Mps1 Cell Cycle Function

Taebo Sim, Stefan Knapp, Panagis Filippakopoulos, 2010, Nature chemical biology.

The dTAG system for immediate and target-specific protein degradation

James E. Bradner, Kwok-Kin Wong, Amanda Souza, 2018, Nature Chemical Biology.

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry

Satpal Virdee, Dario R. Alessi, Nathanael S. Gray, 2014, Nature Communications.