W. F. Hoffman

发表

Design of Digital Loaded-Line Phase-Shift Networks for Microwave Thin-Film Applications

F. L. Opp, W. F. Hoffman, W. F. Hoffman, 1968 .

Design of Digital Loaded-Line Phase-Shift Networks for Microwave Thin-Film Applications

F. L. Opp, W. F. Hoffman, 1968 .

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 4. Side chain ester derivatives of mevinolin.

W. F. Hoffman, P. Anderson, A. Alberts, 1986, Journal of medicinal chemistry.

Property-based design of KDR kinase inhibitors.

W. F. Hoffman, G. McGaughey, K. Rickert, 2004, Current medicinal chemistry.

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 1. Structural modification of 5-substituted 3,5-dihydroxypentanoic acids and their lactone derivatives.

B. E. Evans, W. F. Hoffman, A. Deana, 1985, Journal of Medicinal Chemistry.

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 3. 7-(3,5-Disubstituted [1,1'-biphenyl]-2-yl)-3,5-dihydroxy-6-heptenoic acids and their lactone derivatives.

W. F. Hoffman, P. Anderson, J. Hirshfield, 1986, Journal of Medicinal Chemistry.

The synthesis of [3H]L‐734,217, an orally active fibrinogen receptor antagonist

W. F. Hoffman, H. Burns, G. Hartman, 1996 .

Nonpeptide αvβ3 antagonists. Part 2: constrained glycyl amides derived from the RGD tripeptide

W. F. Hoffman, C. Leu, J. Huff, 2002 .

The discovery of N-(1,3-thiazol-2-yl)pyridin-2-amines as potent inhibitors of KDR kinase.

W. F. Hoffman, G. McGaughey, R. Hungate, 2004, Bioorganic & medicinal chemistry letters.

Nonpeptide αvβ3 Antagonists. 1. Transformation of a Potent, Integrin-Selective αIIbβ3 Antagonist into a Potent αvβ3 Antagonist

W. F. Hoffman, C. Leu, J. Huff, 2000 .

Nonpeptide alpha(v)beta(3) antagonists. Part 2: constrained glycyl amides derived from the RGD tripeptide.

W. F. Hoffman, C. Leu, J. Huff, 2002, Bioorganic & medicinal chemistry letters.

Nonpeptide alpha(v)beta(3) antagonists. 1. Transformation of a potent, integrin-selective alpha(IIb)beta(3) antagonist into a potent alpha(v)beta(3) antagonist.

W. F. Hoffman, C. Leu, J. Huff, 2000, Journal of medicinal chemistry.

Optimization of the indolyl quinolinone class of KDR (VEGFR-2) kinase inhibitors: effects of 5-amido- and 5-sulphonamido-indolyl groups on pharmacokinetics and hERG binding.

W. F. Hoffman, C. Buser, B. Wong, 2004, Bioorganic & medicinal chemistry letters.

Nonpeptide glycoprotein IIB/IIIA inhibitors. 19. A new design paradigm employing linearly minimized, centrally constrained, exosite inhibitors.

W. F. Hoffman, R. Gould, G. Hartman, 1999, Bioorganic & medicinal chemistry letters.

Kinesin spindle protein (KSP) inhibitors. Part 3: synthesis and evaluation of phenolic 2,4-diaryl-2,5-dihydropyrroles with reduced hERG binding and employment of a phosphate prodrug strategy for aqueous solubility.

W. F. Hoffman, Youwei Yan, L. Kuo, 2006, Bioorganic & medicinal chemistry letters.

Optimization of a pyrazolo[1,5-a]pyrimidine class of KDR kinase inhibitors: improvements in physical properties enhance cellular activity and pharmacokinetics.

W. F. Hoffman, R. Hungate, R. Kendall, 2002, Bioorganic & medicinal chemistry letters.

Synthesis and initial SAR studies of 3,6-disubstituted pyrazolo[1,5-a]pyrimidines: a new class of KDR kinase inhibitors.

W. F. Hoffman, R. Hungate, R. Kendall, 2002, Bioorganic & medicinal chemistry letters.

3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE INHIBITORS. I. STRUCTURAL MODIFICATION OF 5-SUBSTITUTED 3,5-DIHYDROXYPENTANOIC ACIDS AND THEIR LACTONE DERIVATIVES

W. F. Hoffman, A. Deana, A. Alberts, 1985 .

A simple and inexpensive synthesis of 4-(aminomethyl)-L-phenylalanine

W. F. Hoffman, G. Stokker, C. Homnick, 1993 .

Some Problems in Lichen Metabolism: Studies with the Mycobionts Cetraria islandica and Cladonia papillarial

W. F. Hoffman, W. Eder, J. L. Bloomer, 1970 .

Biotransformation of lovastatin. I. Structure elucidation of in vitro and in vivo metabolites in the rat and mouse.

W. F. Hoffman, B. Arison, E. Ulm, 1990, Drug metabolism and disposition: the biological fate of chemicals.

Discovery and evaluation of 3-(5-thien-3-ylpyridin-3-yl)-1H-indoles as a novel class of KDR kinase inhibitors.

W. F. Hoffman, R. Hungate, R. Kendall, 2003, Bioorganic & medicinal chemistry letters.

(ACYLARYLOXY)ACETIC ACID DIURETICS. 3. 2,3-DIHYDRO-5-ACYL-2-BENZOFURANCARBOXYLIC ACIDS, A NEW CLASS OF URICOSURIC DIURETICS

W. F. Hoffman, J. Springer, E. Cragoe, 1981 .

(Acylaryloxy)acetic acid diuretics. 3. 2,3-Dihydro-5-acyl-2-benzofurancarboxylic acids, a new class of uricosuric diuretics.

W. F. Hoffman, J. Springer, E. Cragoe, 1981, Journal of medicinal chemistry.

Biosynthesis of (+)-protolichesterinic acid in Cetraria islandica

W. F. Hoffman, W. Eder, J. L. Bloomer, 1970 .

3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Inhibitors. Part 3.

W. F. Hoffman, P. Anderson, J. Hirshfield, 1986 .

3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase Inhibitors. Part 4. Side Chain Ester Derivatives of Mevinolin.

W. F. Hoffman, P. Anderson, A. Alberts, 1986 .

Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP.

W. F. Hoffman, Youwei Yan, P. Coleman, 2006, Bioorganic & medicinal chemistry letters.

Substituted 2-aminopyridines as inhibitors of nitric oxide synthases.

W. F. Hoffman, Kenny K. Wong, M. Maccoss, 2000, Bioorganic & medicinal chemistry letters.