Stephan A. Ohnmacht

发表

Stephan A. Ohnmacht, 2010 .

Small-molecule quadruplex-targeted drug discovery.

Stephen Neidle, Stephan A. Ohnmacht, S. Neidle, 2014, Bioorganic & medicinal chemistry letters.

Optimization of anti-proliferative activity using a screening approach with a series of bis-heterocyclic G-quadruplex ligands.

Stephan A. Ohnmacht, G. Vignaroli, S. Neidle, 2013, Bioorganic & medicinal chemistry letters.

Sequences in the HSP90 promoter form G-quadruplex structures with selectivity for disubstituted phenyl bis-oxazole derivatives.

Stephan A. Ohnmacht, M. Micco, M. Zloh, 2012, Bioorganic & medicinal chemistry letters.

Scale-Up of Flow-Assisted Synthesisof C2-Symmetric Chiral PyBoxLigands

Claudio Battilocchio, Steven V. Ley, Rainer E. Martin, 2012 .

Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds.

Stephan A. Ohnmacht, G. Werstuck, Anna J Kim, 2004, Bioorganic & medicinal chemistry letters.

Synthesis, G‐Quadruplex Stabilisation, Docking Studies, and Effect on Cancer Cells of Indolo[3,2‐b]quinolines with One, Two, or Three Basic Side Chains

Stephan A. Ohnmacht, S. Neidle, J. Lavrado, 2013, ChemMedChem.

A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer

Stephan A. Ohnmacht, J. Šponer, J. Šponer, 2015, Scientific Reports.

Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule

Stephan A. Ohnmacht, S. Balasubramanian, S. Neidle, 2018, Journal of medicinal chemistry.

Solid-phase Suzuki cross-coupling reactions using a phosphine ligand based on a phospha-adamantane framework

Stephan A. Ohnmacht, K. Bleicher, J. McNulty, 2004 .

Synthesis and Initial in Vivo Studies with [(11)C]SB-216763: The First Radiolabeled Brain Penetrative Inhibitor of GSK-3.

Young T. Hong, Stephan A. Ohnmacht, X. Shao, 2015, ACS medicinal chemistry letters.

A G-quadruplex-binding compound shows potent activity in human gemcitabine-resistant pancreatic cancer cells

Stephan A. Ohnmacht, S. Neidle, C. Marchetti, 2020, Scientific Reports.

Macrocyclic naphthalene diimides as G-quadruplex binders.

Stephan A. Ohnmacht, V. Tumiatti, A. Milelli, 2015, Bioorganic & medicinal chemistry.

Inhibition of oxidative metabolism of tocopherols with omega-N-heterocyclic derivatives of vitamin E.

Stephan A. Ohnmacht, J. Atkinson, R. Parker, 2008, Bioorganic & medicinal chemistry.

Direct arylations on water: synthesis of 2,5-disubstituted oxazoles balsoxin and texaline.

Stephan A. Ohnmacht, M. Greaney, A. Culshaw, 2008, Chemical communications.

Direct arylations of 2H-indazoles on water.

Stephan A. Ohnmacht, M. Greaney, A. Culshaw, 2010, Organic letters.

Structure-based design and evaluation of naphthalene diimide G-quadruplex ligands as telomere targeting agents in pancreatic cancer cells.

Stephen Neidle, Mekala Gunaratnam, Stephan A. Ohnmacht, 2013, Journal of medicinal chemistry.

Indolo[3,2‐c]quinoline G‐Quadruplex Stabilizers: a Structural Analysis of Binding to the Human Telomeric G‐Quadruplex

Stephan A. Ohnmacht, S. Neidle, J. Lavrado, 2015, ChemMedChem.

Assignment of the 1H and 13C NMR of tocotrienols

Stephan A. Ohnmacht, J. Atkinson, R. Simionescu, 2008, Magnetic resonance in chemistry : MRC.

Downregulation of androgen receptor transcription by promoter g-quadruplex stabilization as a potential alternative treatment for castrate-resistant prostate cancer.

Stephan A. Ohnmacht, S. Balasubramanian, M. Micco, 2013, Biochemistry.

Substituted Naphthalenediimide Compounds Bind Selectively to Two Human Quadruplex Structures with Parallel Topology.

Stephan A. Ohnmacht, R. Angell, S. Neidle, 2020, ACS medicinal chemistry letters.

KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines

Stephan A. Ohnmacht, S. Neidle, J. Lavrado, 2015, Scientific Reports.

The influence of positional isomerism on G-quadruplex binding and anti-proliferative activity of tetra-substituted naphthalene diimide compounds.

Stephan A. Ohnmacht, S. Neidle, M. Gunaratnam, 2013, Bioorganic & medicinal chemistry.

Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives.

Stephan A. Ohnmacht, E. Novellino, B. Pagano, 2016, Journal of medicinal chemistry.

Targeting KRAS Oncogene in Colon Cancer Cells with 7-Carboxylate Indolo[3,2-b]quinoline Tri-Alkylamine Derivatives

Stephan A. Ohnmacht, S. Neidle, J. Lavrado, 2015, PloS one.

Xanthene and Xanthone Derivatives as G-Quadruplex Stabilizing Ligands

Stephan A. Ohnmacht, S. Neidle, G. Ortaggi, 2013, Molecules.

Discovery of new G-quadruplex binding chemotypes.

Stephan A. Ohnmacht, S. Neidle, Rupesh K. Nanjunda, 2014, Chemical communications.