Joel Karpiak

Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65

Xin Chen, Sheng Wang, Jian Jin, 2015, Nature.

In silico analysis of the binding of agonists and blockers to the β2-adrenergic receptor.

Santiago Vilar, Stefano Costanzi, Joel Karpiak, 2011, Journal of molecular graphics & modelling.

Design, synthesis, crystal structures, and antimicrobial activity of sulfonamide boronic acids as β-lactamase inhibitors.

Fabio Prati, Richard Bonnet, Kerim Babaoglu, 2010, Journal of medicinal chemistry.

Selectivity Challenges in Docking Screens for GPCR Targets and Antitargets

Dahlia R. Weiss, Bryan L Roth, Brian K Shoichet, 2018, Journal of medicinal chemistry.

Structure-based ligand discovery for the protein–protein interface of chemokine receptor CXCR4

Michael M. Mysinger, Dahlia R. Weiss, Brian K Shoichet, 2012, Proceedings of the National Academy of Sciences.

In silico design of novel probes for the atypical opioid receptor MRGPRX2

Jing Liu, Jian Jin, John D. McCorvy, 2016, Nature chemical biology.

Quantification of the transferability of a designed protein specificity switch reveals extensive epistasis in molecular recognition

Tanja Kortemme, Noah Ollikainen, Joel Karpiak, 2014, Proceedings of the National Academy of Sciences.