Theodore A. Martinot

发表

Process Safety Considerations for the Supply of a High-Energy Oxadiazole IDO1-Selective Inhibitor

Lu Chen, Theodore A. Martinot, Michael J. Ardolino, 2019, Organic Process Research & Development.

Data-Rich Experimentation Enables Palladium-Catalyzed Couplings of Piperidines and Five-Membered (Hetero)aromatic Electrophiles

Theodore A. Martinot, Aaron C. Sather, 2019, Organic Process Research & Development.

Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing.

Theodore A. Martinot, Yongxin Han, N. Solban, 2022, Journal of medicinal chemistry.

Development of a Zinc-Mediated Approach to a 2,3-cis-Pyrrolidine Arginase Inhibitor

Theodore A. Martinot, J. Qi, C. Q. He, 2020 .

Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy.

Theodore A. Martinot, J. O'neil, J. Cumming, 2020, ACS medicinal chemistry letters.

Total synthesis and biological evaluation of Amaryllidaceae alkaloids: narciclasine, ent-7-deoxypancratistatin, regioisomer of 7-deoxypancratistatin, 10b-epi-deoxypancratistatin, and truncated derivatives.

Theodore A. Martinot, T. Hudlický, U. Rinner, 2002, The Journal of organic chemistry.

Synthesis, structure, and biological evaluation of novel N- and O-linked diinositols.

Theodore A. Martinot, T. Hudlický, K. Abboud, 2002, Journal of the American Chemical Society.

Total synthesis and biological evaluation of Amaryllidaceae alkaloids: narciclasine, ent-7-deoxypancratistatin, regioisomer of 7-deoxypancratistatin, 10b-epi-deoxypancratistatin, and truncated derivatives.

Theodore A. Martinot, T. Hudlický, U. Rinner, 2002, The Journal of organic chemistry.

A short chemoenzymatic synthesis of (+)-narciclasine

Theodore A. Martinot, T. Hudlický, D. Gonzalez, 1999 .

Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy.

Theodore A. Martinot, Michael J. Ardolino, Xiao Wang, 2019, ACS medicinal chemistry letters.

Development of a Manufacturing Process for an HCV Protease Inhibitor Candidate Molecule

Theodore A. Martinot, M. Aizenberg, B. Littler, 2015 .

Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors.

Theodore A. Martinot, J. Cumming, A. Palani, 2021, ACS medicinal chemistry letters.

Novel O- and N-Linked Inositol Oligomers: A New Class of Unnatural Saccharide Mimics

Theodore A. Martinot, T. Hudlický, B. Paul, 2001 .

Novel O‐ and N‐Linked Inositol Oligomers: A New Class of Unnatural Saccharide Mimics

Theodore A. Martinot, T. Hudlický, B. Paul, 2001 .

Carbamate and N-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors.

Patrick J. Curran, Theodore A. Martinot, Yongxin Han, 2021, ACS medicinal chemistry letters.

Racemic Synthesis of a Key 1,4-Dihydro-2H-spiro[isoquinoline-3,4′-piperidin]-3′-ol Building Block

Leo A. Joyce, Theodore A. Martinot, Matthew L. Maddess, 2022, Organic Process Research & Development.

A Design of Experiments Approach to a Robust Final Deprotection and Reactive Crystallization of IPI-926, A Novel Hedgehog Pathway Inhibitor

Theodore A. Martinot, J. Helble, A. Côté, 2015 .

Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease.

Theodore A. Martinot, Michael J. Ardolino, Matthew L. Maddess, 2022, Journal of medicinal chemistry.

Artificial genetic systems: exploiting the "aromaticity" formalism to improve the tautomeric ratio for isoguanosine derivatives.

Steven A Benner, Theodore A. Martinot, S. Benner, 2004, The Journal of organic chemistry.

Synthesis of the bis-tetrahydropyran core of amphidinol 3.

Theodore A. Martinot, M. Crimmins, T. J. Martin, 2010, Organic letters.

PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections

Theodore A. Martinot, L. Coussens, K. Fisch, 2024, Science Translational Medicine.