Boshi Huang

发表

Discovery of bioactive molecules from CuAAC click-chemistry-based combinatorial libraries.

Peng Zhan, Xinyong Liu, Xueshun Wang, 2016, Drug discovery today.

Facile Synthesis of Derivatives of 1,1,3‐Trioxo‐2H,4H‐pyrrolo[1,2‐b][1,2,4,6]thiatriazine: A New Heterocyclic System.

Peng Zhan, Boshi Huang, Boshi Huang, 2014 .

Synthesis and Biological Evaluation of a Series of 2‐((1‐substituted‐1H‐1,2,3‐triazol‐4‐yl)methylthio)‐6‐(naphthalen‐1‐ylmethyl)pyrimidin‐4(3H)‐one As Potential HIV‐1 Inhibitors

Peng Zhan, Dongwei Kang, Christophe Pannecouque, 2015, Chemical biology & drug design.

Design, Synthesis, and Evaluation of Thiophene[3,2-d]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles.

Peng Zhan, Xiao Ding, Dongwei Kang, 2016, Journal of medicinal chemistry.

Facile Synthesis of Derivatives of 1,1,3‐Trioxo‐2H,4H‐pyrrolo[1,2‐b][1,2,4,6]thiatriazine: A New Heterocyclic System

Peng Zhan, Boshi Huang, Boshi Huang, 2013 .

Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant.

Peng Zhan, Xiao Ding, Ye Tian, 2018, Journal of medicinal chemistry.

Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles.

Peng Zhan, F. J. Luque, Ye Tian, 2019, Journal of medicinal chemistry.

Discovery of novel DAPY-IAS hybrid derivatives as potential HIV-1 inhibitors using molecular hybridization based on crystallographic overlays.

Peng Zhan, Xueshun Wang, Christophe Pannecouque, 2017, Bioorganic & medicinal chemistry.

Medicinal chemistry insights in the discovery of novel LSD1 inhibitors.

Peng Zhan, Xueshun Wang, Takayoshi Suzuki, 2015, Epigenomics.

Structure-Based Optimization of Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Resistance-Associated Variants.

Peng Zhan, Xiao Ding, Ye Tian, 2017, Journal of medicinal chemistry.

First discovery of novel 3-hydroxy-quinazoline-2,4(1H,3H)-diones as specific anti-vaccinia and adenovirus agents via ‘privileged scaffold’ refining approach

Peng Zhan, Lieve Naesens, Heng Zhang, 2016, Bioorganic & Medicinal Chemistry Letters.