Thomas M. Razler

发表

Development and Implementation of a Quality Control Strategy for an Atropisomer Impurity Grounded in a Risk-Based Probabilistic Design Space

Jose E. Tabora, Federico Lora Gonzalez, Eric C. Huang, 2019 .

From Drying Kinetics, Solvate Structure, Particle Morphology, and Modeling to Optimal Drying Protocol

Thomas M. Razler, Mark D. Lindrud, L. Dimemmo, 2017 .

Development of a Practical Synthesis of Functionalized Azaxanthene-Derived Nonsteroidal Glucocorticoid Receptor Modulators

Thomas M. Razler, D. Conlon, Steven A. Tymonko, 2016 .

Adventures in Atropisomerism: Total Synthesis of a Complex Active Pharmaceutical Ingredient with Two Chirality Axes.

Jason M. Stevens, Thomas M. Razler, Antonio Ramirez, 2018, Organic letters.

Phorboxazole Synthetic Studies: Design, Synthesis and Biological Evaluation of Phorboxazole A and Hemi-Phorboxazole A Related Analogues.

Thomas M. Razler, T. Molinski, B. I. Morinaka, 2011, Tetrahedron.

(+)-Phorboxazole A synthetic studies. A highly convergent, second generation total synthesis of (+)-phorboxazole A.

Thomas M. Razler, T. Ishikawa, Amos B. Smith, 2005, Organic letters.

Evolution of the Petasis-Ferrier union/rearrangement tactic: construction of architecturally complex natural products possessing the ubiquitous cis-2,6-substituted tetrahydropyran structural element.

Thomas M. Razler, R. J. Fox, Amos B. Smith, 2008, Accounts of chemical research.

Nickel-Catalyzed Synthesis of Quinazolinediones.

Thomas M. Razler, E. Simmons, G. Beutner, 2017, Organic letters.

Development of a Kilogram-Scale Process for the Enantioselective Synthesis of 3-Isopropenyl-cyclohexan-1-one via Rh/DTBM-SEGPHOS-Catalyzed Asymmetric Hayashi Addition Enabled by 1,3-Diol Additives

Thomas M. Razler, Y. Qiu, E. Simmons, 2017 .

Dichlorobis(cyclopentadienyl)zirconium

Thomas M. Razler, Y. Hanzawa, T. Taguchi, 2010 .

A second-generation total synthesis of (+)-phorboxazole A.

Thomas M. Razler, T. Ishikawa, Amos B. Smith, 2008, The Journal of organic chemistry.

Synthesis of pyrimido[4,5-b]indoles and benzo[4,5]furo[2,3-d]pyrimidines via palladium-catalyzed intramolecular arylation

Thomas M. Razler, P. Jackson, Yue Zhang, 2002 .

Mono-Oxidation of Bidentate Bis-phosphines in Catalyst Activation: Kinetic and Mechanistic Studies of a Pd/Xantphos-Catalyzed C-H Functionalization.

Michael Schmidt, Martin D. Eastgate, Yining Ji, 2015, Journal of the American Chemical Society.

Evolution of the Petasis-Ferrier union/rearrangement tactic: construction of architecturally complex natural products possessing the ubiquitous cis-2,6-substituted tetrahydropyran structural element.

Thomas M. Razler, R. J. Fox, Amos B. Smith, 2008, Accounts of chemical research.

Synthesis and biological evaluation of phorboxazole congeners leading to the discovery and preparative-scale synthesis of (+)-chlorophorboxazole a possessing picomolar human solid tumor cell growth inhibitory activity.

Thomas M. Razler, Amos B. Smith, Amos B Smith, 2008, The Journal of organic chemistry.

A preparatively convenient ligand-free catalytic PEG 2000 Suzuki-Miyaura coupling.

Thomas M. Razler, Ruiling Fu, R. Khan, 2009, The Journal of organic chemistry.

Adventures in Atropisomerism: Development of a Robust, Diastereoselective, Lithium-Catalyzed Atropisomer-Forming Active Pharmaceutical Ingredient Step

Thomas M. Razler, Antonio Ramirez, S. Wisniewski, 2018, Organic Process Research & Development.

Design and synthesis of a potent phorboxazole C(11-15) acetal analogue.

Thomas M. Razler, Amos B. Smith, Amos B Smith, 2006, Organic letters.

A Robust Three-Step Telescoped Synthesis of Electron- Deficient Amide Substituted Arylboronic Acids

Thomas M. Razler, D. Conlon, Jason Zhu, 2011 .

Degradation kinetics and mechanism of an oxadiazole derivative, design of a stable drug product for BMS-708163, a γ-secretase inhibitor drug candidate.

Feng Qian, Thomas M. Razler, M. Hussain, 2012, Journal of pharmaceutical sciences.

Inhibitors of unactivated p38 MAP kinase.

Thomas M. Razler, M. Reuman, Xun Li, 2006, Bioorganic & medicinal chemistry letters.

(+)-Phorboxazole A synthetic studies. Identification of a series of highly cytotoxic C(45-46) analogues.

Thomas M. Razler, Amos B. Smith, G. Pettit, 2005, Organic letters.

Synthesis of Pyrimido[4,5-b]indoles and Benzo[4,5]furo[2,3-d]pyrimidines via Palladium-Catalyzed Intramolecular Arylation.

Thomas M. Razler, P. Jackson, Zhang Yue-mei, 2003 .