M C Nicklaus

发表

Use of computer graphics in drug design.

G W Milne, M C Nicklaus, 1993, NIDA research monograph.

Internet resources integrating many small-molecule databases1

M C Nicklaus, M Sitzmann, I V Filippov, 2008, SAR and QSAR in environmental research.

Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.

M C Nicklaus, Y. Pommier, N. Neamati, 1997, Journal of medicinal chemistry.

Pharmacophores in drug design and discovery.

M C Nicklaus, G. Milne, M. Nicklaus, 1998, SAR and QSAR in environmental research.

HIV-1 integrase pharmacophore: discovery of inhibitors through three-dimensional database searching.

M C Nicklaus, Y. Pommier, N. Neamati, 1997, Journal of medicinal chemistry.

Identification of HIV-1 integrase inhibitors via three-dimensional database searching using ASV and HIV-1 integrases as targets.

Alexander D. MacKerell, M C Nicklaus, Y. Pommier, 2000, Bioorganic & medicinal chemistry.

Discovery of novel, non-peptide HIV-1 protease inhibitors by pharmacophore searching.

M C Nicklaus, G. Milne, M. Nicklaus, 1996, Journal of medicinal chemistry.

Discovery of HIV-1 integrase inhibitors by pharmacophore searching.

M C Nicklaus, T R Burke, Y. Pommier, 1997, Journal of medicinal chemistry.

Conformational changes of small molecules binding to proteins.

M C Nicklaus, G. Milne, M. Nicklaus, 1995, Bioorganic & medicinal chemistry.

Conformationally constrained analogues of diacylglycerol. 18. The incorporation of a hydroxamate moiety into diacylglycerol-lactones reduces lipophilicity and helps discriminate between sn-1 and sn-2 binding modes to protein kinase C (PK-C). Implications for isozyme specificity.

M C Nicklaus, P. Blumberg, M. Nicklaus, 2001, Journal of medicinal chemistry.

Interactions of conformationally biased north and south 2'-fluoro-2', 3'-dideoxynucleoside 5'-triphosphates with the active site of HIV-1 reverse transcriptase.

M C Nicklaus, S. Sarafianos, H. Mitsuya, 2000, Biochemistry.