Kosuke Dodo

发表

Image-based screen capturing misfolding status of Niemann-Pick type C1 identifies potential candidates for chaperone drugs

Mikiko Sodeoka, Yuichi Hashimoto, Kenji Ohgane, 2020, PloS one.

The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA.

Shintaro Iwasaki, Kaori Fukuzawa, Nicholas T Ingolia, 2019, Molecular cell.

Imaging of EdU, an alkyne-tagged cell proliferation probe, by Raman microscopy.

Satoshi Kawata, Katsumasa Fujita, Masaya Okada, 2011, Journal of the American Chemical Society.

Raman and SERS microscopy for molecular imaging of live cells

Satoshi Kawata, Katsumasa Fujita, Jun Ando, 2013, Nature Protocols.

Novel Raman-tagged sphingomyelin that closely mimics original raft-forming behavior.

Jun Ando, Hiroyuki Yamakoshi, Kosuke Dodo, 2015, Bioorganic & medicinal chemistry.

Discovery of oxysterol-derived pharmacological chaperones for NPC1: implication for the existence of second sterol-binding site.

Kenji Ohgane, Yuichi Hashimoto, Kosuke Dodo, 2013, Chemistry & biology.

A sensitive and specific Raman probe based on bisarylbutadiyne for live cell imaging of mitochondria.

Satoshi Kawata, Katsumasa Fujita, Jun Ando, 2015, Bioorganic & medicinal chemistry letters.

Alkyne-tag Raman imaging for visualization of mobile small molecules in live cells.

Satoshi Kawata, Katsumasa Fujita, Jun Ando, 2012, Journal of the American Chemical Society.

Structure-activity relationships of oxysterol-derived pharmacological chaperones for Niemann-Pick type C1 protein.

Kenji Ohgane, Yuichi Hashimoto, Tomomi Noguchi-Yachide, 2014, Bioorganic & medicinal chemistry letters.

Phenanthridin-6-one derivatives as the first class of non-steroidal pharmacological chaperones for Niemann-Pick disease type C1 protein.

Hiromitsu Fukuda, Minoru Ishikawa, Kenji Ohgane, 2017, Bioorganic & medicinal chemistry letters.

Structure-activity relationship studies of Niemann-Pick type C1-like 1 (NPC1L1) ligands identified by screening assay monitoring pharmacological chaperone effect.

Kenji Ohgane, Yuichi Hashimoto, Kosuke Dodo, 2013, Bioorganic & medicinal chemistry.

Structure-activity relationship study of non-steroidal NPC1L1 ligands identified through cell-based assay using pharmacological chaperone effect as a readout.

Hiromitsu Fukuda, Kenji Ohgane, Yuichi Hashimoto, 2014, Bioorganic & medicinal chemistry.

Alkyne-Tag SERS Screening and Identification of Small-Molecule-Binding Sites in Protein.

Satoshi Kawata, Katsumasa Fujita, Jun Ando, 2016, Journal of the American Chemical Society.

Sphingomyelin distribution in lipid rafts of artificial monolayer membranes visualized by Raman microscopy

Katsumasa Fujita, Jun Ando, Hiroyuki Yamakoshi, 2015, Proceedings of the National Academy of Sciences.