Rachelle S. Singleton

Modls: Post-translational modification localization scoring with automatic specificity expansion

David C. Trudgian, Benedikt M. Kessler, Rachelle S. Singleton, 2012 .

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

Rachelle S. Singleton, P. Ratcliffe, M. Coleman, 2014, Proceedings of the National Academy of Sciences.

The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity

Rachelle S. Singleton, P. Ratcliffe, B. Kessler, 2012, EMBO reports.

The bioreductive prodrug PR-104A is activated under aerobic conditions by human aldo-keto reductase 1C3.

Rachelle S. Singleton, S. Fox, W. Wilson, 2010, Cancer research.

Quantitative Mass Spectrometry Reveals Dynamics of Factor-inhibiting Hypoxia-inducible Factor-catalyzed Hydroxylation

Rachelle S. Singleton, P. Ratcliffe, R. Fischer, 2011, The Journal of Biological Chemistry.

Mechanism of Action and Preclinical Antitumor Activity of the Novel Hypoxia-Activated DNA Cross-Linking Agent PR-104

Rachelle S. Singleton, W. Denny, W. Wilson, 2007, Clinical Cancer Research.

DNA cross-links in human tumor cells exposed to the prodrug PR-104A: relationships to hypoxia, bioreductive metabolism, and cytotoxicity.

Rachelle S. Singleton, W. Wilson, M. Dorie, 2009, Cancer research.

The bioreductive prodrug PR-104A is activated under aerobic conditions by human aldo-keto reductase 1C3.

Rachelle S. Singleton, S. Fox, W. Wilson, 2010, Cancer research.