Maria Deak

发表

MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm.

Hans C Clevers, Jérôme Boudeau, Annette F Baas, 2003, The EMBO journal.

High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site

David Komander, Ricardo M Biondi, Maria Deak, 2002, The EMBO journal.

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

Miratul M. K. Muqit, Dario R. Alessi, Maria Deak, 2012, Open Biology.

Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C‐terminal residues of PKA

Maria Deak, A. Casamayor, D. Alessi, 2000, The EMBO journal.

Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress

Dario R. Alessi, Jérôme Boudeau, Maria Deak, 2007, The Journal of cell biology.

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

Colin B. Reese, Alan Ashworth, Dario R. Alessi, 1997, Current Biology.

Structure of the LKB1-STRAD-MO25 Complex Reveals an Allosteric Mechanism of Kinase Activation

Maria Deak, Dario R Alessi, D. V. van Aalten, 2009, Science.

MO25α/β interact with STRADα/β enhancing their ability to bind, activate and localize LKB1 in the cytoplasm

Hans Clevers, Dario R. Alessi, Jérôme Boudeau, 2003 .

Crystal Structure of the PTPL1/FAP-1 Human Tyrosine Phosphatase Mutated in Colorectal Cancer

Maria Deak, Dario R Alessi, D. V. van Aalten, 2004, Journal of Biological Chemistry.

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1

Jérôme Boudeau, Maria Deak, T. Mäkelä, 2004, The EMBO journal.

High-Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate

Maria Deak, Dario R Alessi, D. Alessi, 2002, Current Biology.

MSK1 activity is controlled by multiple phosphorylation sites.

Maria Deak, J. Arthur, D. Campbell, 2005, The Biochemical journal.

A phosphoserine/threonine‐binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation

Maria Deak, S. Gammeltoft, R. Biondi, 2002, The EMBO journal.

The PIF‐binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB

Maria Deak, Agnieszka Kieloch, D. Alessi, 2001, The EMBO journal.

Crystal structure of MO25α in complex with the C terminus of the pseudo kinase STE20-related adaptor

Jérôme Boudeau, Maria Deak, Dario R Alessi, 2004, Nature Structural &Molecular Biology.

Role of T-loop Phosphorylation in PDK1 Activation, Stability, and Substrate Binding*

Dario R. Alessi, David Komander, Maria Deak, 2005, Journal of Biological Chemistry.