Raymond S. H. Yang

发表

A physiologically-based pharmacokinetic model of methotrexate incorporating hepatic excretion via multidrug-resistance-associated protein 2 (Mrp2) in mice, rats, dogs, and humans

Manupat Lohitnavy, Ornrat Lohitnavy, Yasong Lu, 2017, 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

Physiologically Based Pharmacokinetic and Pharmacodynamic Modeling

Melvin E. Andersen, Brad Reisfeld, Raymond S. H. Yang, 2004 .

Toxicology and Risk Assessment of Chemical Mixtures and Multiple Stressors

Raymond S. H. Yang, 2018 .

Predicting Activation Enthalpies of Cytochrome-P450-Mediated Hydrogen Abstractions. 2. Comparison of Semiempirical PM3, SAM1, and AM1 with a Density Functional Theory Method

Arthur N. Mayeno, Jonathan L. Robinson, Brad Reisfeld, 2009, J. Chem. Inf. Model..

52. Evaluation of the Adequacy of the Mixture Formula (Em) in Preventing Overexposure to Some Neurotoxic Gasoline Components

M. Andersen, Raymond S. H. Yang, J. Dennison, 2001 .

Characterization of gene expression changes associated with MNNG, arsenic, or metal mixture treatment in human keratinocytes: application of cDNA microarray technology.

Raymond S H Yang, Raymond S. H. Yang, D. Bae, 2002, Environmental health perspectives.

Critical analysis of literature on low-dose synergy for use in screening chemical mixtures for risk assessment

Raymond S. H. Yang, K. Crofton, A. Boobis, 2011, Critical reviews in toxicology.

Toxicology of chemical mixtures : case studies, mechanisms, and novel approaches

Raymond S. H. Yang, 1994 .

Assessment of the Reproductive and Developmental Toxicity of Pesticide/Fertilizer Mixtures Based on Confirmed Pesticide Contamination in California and Iowa Groundwater

Raymond S. H. Yang, C. Price, M. Marr, 1994 .

17 – Physiologically Based Pharmacokinetic Modeling of Chemical Mixtures

Raymond S. H. Yang, M. Andersen, K. Krishnan, 1994 .

A non-invasive approach to study lifetime exposure and bioaccumulation of PCBs in protected marine mammals: PBPK modeling in harbor porpoises.

Raymond S. H. Yang, A. Covaci, K. Das, 2011, Toxicology and applied pharmacology.

Biochemical reaction network modeling: predicting metabolism of organic chemical mixtures.

Raymond S H Yang, Brad Reisfeld, Arthur N Mayeno, 2005, Environmental science & technology.

Assessment of the reproductive toxicity of a complex mixture of 25 groundwater contaminants in mice and rats.

Robert E. Chapin, Raymond S. H. Yang, Jerrold J. Heindel, 1995 .

Improving the risk assessment of lipophilic persistent environmental chemicals in breast milk

Yu-Mei Tan, Rogelio Tornero-Velez, Judy S. LaKind, 2014, Critical reviews in toxicology.

Physiologically Based Pharmacokinetic Modeling : Science and Applications

Melvin E. Andersen, Harvey J. Clewell, Raymond S. H. Yang, 2005 .

Introduction to Mixtures Toxicology and Risk Assessment

Moiz Mumtaz, Raymond S. H. Yang, William A. Suk, 2010 .

A Physiologically Based Pharmacokinetic Model of Rifampin in Mice

Brad Reisfeld, Raymond S. H. Yang, Michael A. Lyons, 2013, Antimicrobial Agents and Chemotherapy.

The Application of Physiologically Based Pharmacokinetics, Bayesian Population PBPK Modeling, and Biochemical Reaction Network Modeling to Chemical Mixture Toxicology

Raymond S. H. Yang, B. Reisfeld, A. N. Mayeno, 2010 .

Chemical mixture toxicology: from descriptive to mechanistic, and going on to in silico toxicology.

Raymond S. H. Yang, Russell S. Thomas, M. Andersen, 2004, Environmental toxicology and pharmacology.

Development of a physiologically based pharmacokinetic model for volatile fractions of gasoline using chemical lumping analysis.

Raymond S. H. Yang, M. Andersen, H. Clewell, 2004, Environmental science & technology.

Characterization of the Pharmacokinetics of Gasoline Using PBPK Modeling with a Complex Mixtures Chemical Lumping Approach

Melvin E Andersen, Raymond S H Yang, Raymond S. H. Yang, 2003, Inhalation toxicology.

Introduction: A Historical Perspective of the Development and Applications of PBPK Models

Melvin E. Andersen, Harvey J. Clewell, Raymond S. H. Yang, 2005 .

A physiologically based pharmacokinetic model for lactational transfer of PCB 153 with or without PCB 126 in mice

Melvin E. Andersen, Sun Ku Lee, Raymond S. H. Yang, 2007, Archives of Toxicology.

Physiologically based pharmacokinetic/pharmacodynamic modeling of the toxicologic interaction between carbon tetrachloride and Kepone

Melvin E. Andersen, Harihara M. Mehendale, Raymond S. H. Yang, 1996, Archives of Toxicology.

Application of PBPK modeling in support of the derivation of toxicity reference values for 1,1,1-trichloroethane.

Hugh A. Barton, Raymond S. H. Yang, H. El-Masri, 2008, Regulatory toxicology and pharmacology : RTP.

Exploration of an interaction threshold for the joint toxicity of trichloroethylene and 1,1-dichloroethylene: utilization of a PBPK model

Raymond S. H. Yang, Hisham A. El-Masri, John D. Tessari, 2009, Archives of Toxicology.

Integration of PBPK and Reaction Network Modelling: Predictive Xenobiotic Metabolomics

Kenneth F. Reardon, Arthur N. Mayeno, Brad Reisfeld, 2005 .

Statistical analysis of interactive cytotoxicity in human epidermal keratinocytes following exposure to a mixture of four metals

Chris Gennings, W. H. Carter, Raymond S. H. Yang, 2002 .

An In Silico Approach for Evaluating a Fraction-Based, Risk Assessment Method for Total Petroleum Hydrocarbon Mixtures

Linda K. Teuschler, Nina Ching Y. Wang, Glenn E. Rice, 2012, Journal of toxicology.

Comparison of pharmacokinetic interactions and physiologically based pharmacokinetic modeling of PCB 153 and PCB 126 in nonpregnant mice, lactating mice, and suckling pups.

Sun Ku Lee, Raymond S. H. Yang, Y. Ou, 2002, Toxicological sciences : an official journal of the Society of Toxicology.

Inducibility of a molecular bioreporter system by heavy metals

Raymond S. H. Yang, K. Olson, B. Beaty, 1996 .

Computational toxicology: Physiologically based pharmacokinetic models (PBPK) for lifetime exposure and bioaccumulation of polybrominated diphenyl ethers (PBDEs) in marine mammals.

Raymond S. H. Yang, A. Covaci, K. Das, 2012, Environmental pollution.

1 Introduction to Mixtures Toxicology and Risk Assessment

Raymond S. H. Yang, M. Mumtaz, W. Suk, 2010 .

Pharmacokinetics and physiologically-based pharmacokinetic modeling of nanoparticles.

Louis W. Chang, Raymond S. H. Yang, P. Lin, 2010, Journal of nanoscience and nanotechnology.

Acute and Subchronic Toxicity of Ethylenediamine in Laboratory Animals

Raymond S. H. Yang, C. S. Weil, R. Maronpot, 1983 .

Evaluation of Potential Toxicity from Co-Exposure to Three CNS Depressants (Toluene, Ethylbenzene, and Xylene) Under Resting and Working Conditions Using PBPK Modeling

Raymond S. H. Yang, M. Andersen, P. Bigelow, 2005, Journal of occupational and environmental hygiene.

1,3-Dichloropropene.

Raymond S. H. Yang, 1986, Residue reviews.

Hepatic sequestration of chlordecone and hexafluoroacetone evaluated by pharmacokinetic modeling.

Raymond S. H. Yang, M. Andersen, L. Chubb, 2007, Toxicology.

Population Physiologically Based Pharmacokinetic Modeling for the Human Lactational Transfer of PCB-153 with Consideration of Worldwide Human Biomonitoring Results

Raymond S. H. Yang, M. Sohn, T. McKone, 2008, Environmental health perspectives.

Use of Physiologically Based Pharmacokinetic (PBPK) Models in Marine Mammal Toxicology

Raymond S. H. Yang, A. Covaci, K. Das, 2012 .

Physiologically based pharmacokinetic (PBPK) models for lifetime exposure to PCB 153 in male and female harbor porpoises (Phocoena phocoena): model development and evaluation.

Raymond S. H. Yang, A. Covaci, K. Das, 2010, Environmental science & technology.

Quantitative analysis of liver GST-P foci promoted by a chemical mixture of hexachlorobenzene and PCB 126: implication of size-dependent cellular growth kinetics

Raymond S. H. Yang, R. Conolly, M. Reddy, 2008, Archives of Toxicology.

Taste Response of a Bird to Constituents of Arthropod Defensive Secretions

Raymond S. H. Yang, M. R. Kare, 1968 .

A novel, sensitive method for determining benzo[a]pyrene-diones using high-performance liquid chromatography with post-column zinc reduction.

Raymond S. H. Yang, A. N. Mayeno, K. Reardon, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Enzymatic Conjugation and Insecticide Metabolism

Raymond S. H. Yang, 1976 .

Molecular circuits, biological switches, and nonlinear dose-response relationships.

Melvin E Andersen, Raymond S H Yang, Raymond S. H. Yang, 2002, Environmental health perspectives.

Chemical mixtures research: significance and future perspectives.

Raymond S H Yang, William A Suk, Kenneth Olden, 2002, Environmental health perspectives.

Metabolism in vitro of diazinon and diazoxon in susceptible and resistant houseflies

Raymond S. H. Yang, E. Hodgson, W. Dauterman, 1971 .

Gene expression changes associated with altered growth and differentiation in benzo[a]pyrene or arsenic exposed normal human epidermal keratinocytes

Raymond S. H. Yang, D. S. Perez, J. Campain, 2008, Journal of applied toxicology : JAT.

Gene expression patterns as potential molecular biomarkers for malignant transformation in human keratinocytes treated with MNNG, arsenic, or a metal mixture.

Raymond S. H. Yang, D. Bae, J. Campain, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Computational Toxicology of Chloroform: Reverse Dosimetry Using Bayesian Inference, Markov Chain Monte Carlo Simulation, and Human Biomonitoring Data

Arthur N. Mayeno, Brad Reisfeld, Raymond S. H. Yang, 2008, Environmental health perspectives.

Application of biologically based computer modeling to simple or complex mixtures.

Raymond S. H. Yang, R. J. Quann, M. Andersen, 2002, Environmental health perspectives.

Computational and ultrastructural toxicology of a nanoparticle, Quantum Dot 705, in mice.

Ming-Hsien Tsai, Raymond S H Yang, Louis W. Chang, 2008, Environmental science & technology.

Toxicology and Biosafety Evaluations of Quantum Dots

Louis W. Chang, Raymond S. H. Yang, P. Lin, 2011 .

Stochastic simulation of hepatic preneoplastic foci development for four chlorobenzene congeners in a medium-term bioassay.

Raymond S. H. Yang, Russell S. Thomas, M. Andersen, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

An updated physiologically based pharmacokinetic model for hexachlorobenzene: incorporation of pathophysiological states following partial hepatectomy and hexachlorobenzene treatment.

Raymond S. H. Yang, M. Reddy, MANUPAT LOHITNAVY, 2006, Toxicological sciences : an official journal of the Society of Toxicology.

Toxicology studies of a chemical mixture of 25 groundwater contaminants. I: Chemistry development

Raymond S. H. Yang, R. C. Buchanan, T. Goehl, 1989 .

Toxicology of Chemical Mixtures Derived from Hazardous Waste Sites or Application of Pesticides and Fertilizers

Raymond S. H. Yang, 1994 .

Metabolism and pharmacokinetics of ethylenediamine in the rat following oral, endotracheal or intravenous administration

Raymond S. H. Yang, M. J. Tallant, 1982 .

Effect of PCBs on the lactational transfer of methyl mercury in mice: PBPK modeling.

Sun Ku Lee, Raymond S. H. Yang, MANUPAT LOHITNAVY, 2009, Environmental toxicology and pharmacology.

Persistent Tissue Kinetics and Redistribution of Nanoparticles, Quantum Dot 705, in Mice: ICP-MS Quantitative Assessment

Ming-Hsien Tsai, Louis W. Chang, Pinpin Lin, 2007, Environmental health perspectives.

Commentary: some critical issues and concerns related to research advances on the toxicology of chemical mixtures

Raymond S. H. Yang, 1998, Environmental Health Perspectives.

In silico toxicology: simulating interaction thresholds for human exposure to mixtures of trichloroethylene, tetrachloroethylene, and 1,1,1-trichloroethane.

Melvin E Andersen, Raymond S H Yang, Raymond S. H. Yang, 2002, Environmental health perspectives.

Effects of developmental exposure to lead, magnesium and zinc mixtures on spatial learning and expression of NMDA receptor subunit mRNA in Fischer 344 rats.

Raymond S. H. Yang, K. Magnusson, Heike M Newman, 2002, Toxicology letters.

Application of Bayesian population physiologically based pharmacokinetic (PBPK) modeling and Markov chain Monte Carlo simulations to pesticide kinetics studies in protected marine mammals: DDT, DDE, and DDD in harbor porpoises.

Ronny Blust, Adrian Covaci, Liesbeth Weijs, 2013, Environmental science & technology.

BioMOL: a computer-assisted biological modeling tool for complex chemical mixtures and biological processes at the molecular level.

Raymond S H Yang, Kai H Liao, Linda J Broadbelt, 2002, Environmental health perspectives.

1 – Introduction to the Toxicology of Chemical Mixtures

Raymond S. H. Yang, 1994 .

Performance Assessment and Translation of Physiologically Based Pharmacokinetic Models From acslX to Berkeley Madonna, MATLAB, and R Language: Oxytetracycline and Gold Nanoparticles As Case Examples.

Jim E Riviere, Zhoumeng Lin, Raymond S H Yang, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Toxicological Interactions of Chemical Mixtures

Raymond S. H. Yang, Raymond S. H. Yang, 2010 .

Raymond S. H. Yang, M. Andersen, J. Dennison, 2005, Inhalation toxicology.

Hexachloro-1,3-butadiene: toxicology, metabolism, and mechanisms of toxicity.

Raymond S. H. Yang, R. S. Yang, 1988, Reviews of environmental contamination and toxicology.

A lifetime physiologically based pahrmacokinetic model for CB 153 in harbour porpoises : **in silico** tool for predicting concentrations of future lipophilic pollutants?

Raymond S. H. Yang, A. Covaci, K. Das, 2009 .

PBPK modeling of complex hydrocarbon mixtures: gasoline.

Melvin E Andersen, Raymond S H Yang, Moiz M Mumtaz, 2004, Environmental toxicology and pharmacology.

A possible role of multidrug resistance-associated protein 2 (Mrp2) in hepatic excretion of PCB126, an environmental contaminant: PBPK/PD modeling.

Shuichi Hirono, Raymond S H Yang, Ornrat Lohitnavy, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Comment Report Follow up-External Peer Review of a Report on Physiologically Based Pharmacokinetic (PBPK) Modeling for Chloroprene and a Supplemental Analysis of Metabolite Clearance

Raymond S. H. Yang, Yiliang Zhu, D. Kapraun, 2021 .

Lifetime PCB 153 bioaccumulation and pharmacokinetics in pilot whales: Bayesian population PBPK modeling and Markov chain Monte Carlo simulations.

Ronny Blust, Adrian Covaci, Robin McDougall, 2014, Chemosphere.

Carcinogenesis studies in rodents for evaluating risks associated with chemical carcinogens in aquatic food animals.

Raymond S. H. Yang, J. Huff, J. Bucher, 1991, Environmental health perspectives.

A reaction network model for CYP2E1-mediated metabolism of toxicant mixtures.

Raymond S. H. Yang, B. Reisfeld, 2004, Environmental toxicology and pharmacology.

Support of science-based decisions concerning the evaluation of the toxicology of mixtures: a new beginning.

Rory Conolly, Richard Hertzberg, Chris Gennings, 2002, Regulatory toxicology and pharmacology : RTP.

Assessment of the reproductive and developmental toxicity of pesticide/fertilizer mixtures based on confirmed pesticide contamination in California and Iowa groundwater.

Raymond S. H. Yang, C. Price, M. Marr, 1994, Fundamental and applied toxicology : official journal of the Society of Toxicology.

W09-4Pharmacokinetics and toxicology of nanoparticles in drug delivery

Raymond S. H. Yang, 2013 .

Acute and subchronic toxicity of ethylenediamine in laboratory animals.

Raymond S. H. Yang, C. S. Weil, R. Maronpot, 1983, Fundamental and applied toxicology : official journal of the Society of Toxicology.

A proposed approach to study the toxicology of complex mixtures of petroleum products: the integrated use of QSAR, lumping analysis and PBPK/PD modeling.

S M Hays, D P Gaver, K F Reardon, 1997, Environmental health perspectives.

Conjugation of p-nitrophenol with sulfate in larvae of the southern armyworm (Prodenia eridania)

Raymond S. H. Yang, C. F. Wilkinson, 1971 .