Nadinath B. Nillegoda

发表

Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation

Janine Kirstein, Ruedi Aebersold, Rebecca C. Wade, 2015, Nature.

A Network of Ubiquitin Ligases Is Important for the Dynamics of Misfolded Protein Aggregates in Yeast*

Nadinath B. Nillegoda, N. Nillegoda, M. Theodoraki, 2012, The Journal of Biological Chemistry.

Cdc37 has distinct roles in protein kinase quality control that protect nascent chains from degradation and promote posttranslational maturation

Nadinath B. Nillegoda, J. Brodsky, A. K. Mandal, 2007, The Journal of cell biology.

Data-driven large-scale genomic analysis reveals an intricate phylogenetic and functional landscape in J-domain proteins

Nadinath B. Nillegoda, A. Barducci, P. De Los Rios, 2022, bioRxiv.

A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.

Jeffrey J. Jones, Nadinath B. Nillegoda, Lan Huang, 2008, Journal of proteome research.

The Hsp70 chaperone network

Nadinath B. Nillegoda, M. Mayer, B. Bukau, 2019, Nature Reviews Molecular Cell Biology.

Human Hsp70 Disaggregase Reverses Parkinson's-Linked α-Synuclein Amyloid Fibrils.

Nadinath B. Nillegoda, H. Saibil, M. Mayer, 2015, Molecular cell.

Ubr1 and Ubr2 Function in a Quality Control Pathway for Degradation of Unfolded Cytosolic Proteins

Nadinath B. Nillegoda, D. Cyr, A. K. Mandal, 2010, Molecular biology of the cell.

Metazoan Hsp70 machines use Hsp110 to power protein disaggregation.

Bernd Bukau, Kang Chi, Nadinath B. Nillegoda, 2012, The EMBO journal.

Hidden information on protein function in censuses of proteome foldedness

Nadinath B. Nillegoda, C. Ang, D. Cox, 2021, Nature Communications.

Replicative aging impedes stress-induced assembly of a key human protein disaggregase

Nadinath B. Nillegoda, H. Kampinga, D. Cox, 2023, bioRxiv.

Metazoan Hsp70-based protein disaggregases: emergence and mechanisms

Nadinath B. Nillegoda, B. Bukau, N. Nillegoda, 2015, Front. Mol. Biosci..

The Hsp70 chaperone system: distinct roles in erythrocyte formation and maintenance

Nadinath B. Nillegoda, S. Jane, N. Nillegoda, 2021, Haematologica.

Molecular dissection of amyloid disaggregation by human HSP70

Nadinath B. Nillegoda, A. Barducci, P. De Los Rios, 2020, Nature.

HSP40 proteins use class-specific regulation to drive HSP70 functional diversity

Nadinath B. Nillegoda, N. London, B. Bukau, 2020, Nature.

Evolution of an intricate J-protein network driving protein disaggregation in eukaryotes

Nadinath B. Nillegoda, R. Wade, A. Barducci, 2017, eLife.

Hsp70 displaces small heat shock proteins from aggregates to initiate protein refolding

Nadinath B. Nillegoda, B. Bukau, A. Mogk, 2017, The EMBO journal.

Protein Disaggregation in Multicellular Organisms.

Nadinath B. Nillegoda, B. Bukau, N. Nillegoda, 2018, Trends in biochemical sciences.

Monitoring Protein Misfolding by Site-Specific Labeling of Proteins In Vivo

Nadinath B. Nillegoda, B. Bukau, G. Kramer, 2014, PloS one.

In vivo properties of the disaggregase function of J‐proteins and Hsc70 in Caenorhabditis elegans stress and aging

Nadinath B. Nillegoda, R. Morimoto, B. Bukau, 2017, Aging cell.

Metazoan Hsp70 machines use Hsp110 to power protein disaggregation

Nadinath B. Nillegoda, B. Bukau, Heike Rampelt, 2012, The EMBO journal.

J-domain protein chaperone circuits in proteostasis and disease.

Nadinath B. Nillegoda, P. Rios, D. Cyr, 2022, Trends in cell biology.

Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation

Nadinath B. Nillegoda, R. Aebersold, R. Wade, 2015, Nature.

Second Virtual International Symposium on Cellular and Organismal Stress Responses, September 8–9, 2022

Nadinath B. Nillegoda, M. Clark, W. Houry, 2023, Cell Stress and Chaperones.

A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.

Jeffrey J. Jones, Nadinath B. Nillegoda, Lan Huang, 2008, Journal of proteome research.

Functional diversity between HSP70 paralogs caused by variable interactions with specific co-chaperones

Nadinath B. Nillegoda, H. Kampinga, M. Mayer, 2020, The Journal of Biological Chemistry.

Hsp110 Chaperones Control Client Fate Determination in the Hsp70–Hsp90 Chaperone System

Nadinath B. Nillegoda, A. K. Mandal, K. Morano, 2010, Molecular biology of the cell.

Role of molecular chaperones in biogenesis of the protein kinome.

Nadinath B. Nillegoda, A. K. Mandal, M. Theodoraki, 2011, Methods in molecular biology.

Function, evolution, and structure of J-domain proteins

Jason C. Young, Nadinath B. Nillegoda, P. Rios, 2018, Cell Stress and Chaperones.

Ydj1 Protects Nascent Protein Kinases from Degradation and Controls the Rate of Their Maturation

Nadinath B. Nillegoda, A. K. Mandal, N. Nillegoda, 2008, Molecular and Cellular Biology.

Cdc37 has distinct roles in protein kinase quality control that protect nascent chains from degradation and promote posttranslational maturation

Nadinath B. Nillegoda, J. Brodsky, A. K. Mandal, 2007, The Journal of cell biology.

J-domain proteins: From molecular mechanisms to diseases

Nadinath B. Nillegoda, L. Joachimiak, H. Kampinga, 2023, Cell stress & chaperones.

Functional diversity between HSP70 paralogs due to variable interactions with specific co-chaperones.

Nadinath B. Nillegoda, H. Kampinga, B. Bukau, 2020 .

Substrate binding by the yeast Hsp110 nucleotide exchange factor and molecular chaperone Sse1 is not obligate for its biological activities

Nadinath B. Nillegoda, B. Bukau, K. Morano, 2017, Molecular biology of the cell.