Nicholas A Meanwell

Improving Drug Design: An Update on Recent Applications of Efficiency Metrics, Strategies for Replacing Problematic Elements, and Compounds in Nontraditional Drug Space.

Nicholas A Meanwell, N. Meanwell, 2016, Chemical research in toxicology.

4,5-diphenyltriazol-3-ones: openers of large-conductance Ca(2+)-activated potassium (maxi-K) channels.

Qi Gao, Nicholas A Meanwell, Yi Li, 2002, Journal of medicinal chemistry.

2015 Philip S. Portoghese Medicinal Chemistry Lectureship. Curing Hepatitis C Virus Infection with Direct-Acting Antiviral Agents: The Arc of a Medicinal Chemistry Triumph.

Nicholas A Meanwell, N. Meanwell, 2016, Journal of medicinal chemistry.

Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment 13. Synthesis and profiling of a novel amminium prodrug of the HIV-1 attachment inhibitor BMS-585248.

Michael Sinz, Dawn Parker, Kim A Johnson, 2013, Journal of medicinal chemistry.

Discovery of 4-benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): a novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions.

Zheng Yang, Fang Zhao, Timothy P Spicer, 2003, Journal of medicinal chemistry.

Enabled clinical use of an HIV-1 attachment inhibitor through drug delivery.

Peter Timmins, Li Zhu, Nicholas A Meanwell, 2014, Drug discovery today.

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers

Eric T Baldwin, Samuel W Gerritz, Michael Sinz, 2011, Proceedings of the National Academy of Sciences.

Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies.

Qi Gao, Min Gao, Steven Sheriff, 2017, Journal of medicinal chemistry.

The discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection.

Qi Gao, Huabin Sun, Hong Shi, 2014, Journal of medicinal chemistry.