Chung C. Hsu

发表

Considerations for Successful Lyophilization Process Scale‐Up, Technology Transfer, and Routine Production

Samir U. Sane, Chung C. Hsu, 2010 .

Effect of Spray Drying and Subsequent Processing Conditions on Residual Moisture Content and Physical/Biochemical Stability of Protein Inhalation Powders

Steven J. Shire, Chung C. Hsu, Y. Maa, 1998, Pharmaceutical Research.

Mechanisms of aggregate formation and carbohydrate excipient stabilization of lyophilized humanized monoclonal antibody formulations

Steven J. Shire, Chung C. Hsu, S. Shire, 2003, AAPS PharmSci.

Protein Inhalation Powders: Spray Drying vs Spray Freeze Drying

Steven J. Shire, Chung C. Hsu, Y. Maa, 1999, Pharmaceutical Research.

Site-Specific Tryptophan Oxidation Induced by Autocatalytic Reaction of Polysorbate 20 in Protein Formulation

Chung C. Hsu, Victor Ling, X. Lam, 2011, Pharmaceutical Research.

Feasibility Study on Spray-Drying Protein Pharmaceuticals: Recombinant Human Growth Hormone and Tissue-Type Plasminogen Activator

Chung C. Hsu, M. Mumenthaler, Marco Mumenthaler, 2004, Pharmaceutical Research.

The Effect of Formulation Excipients on Protein Stability and Aerosol Performance of Spray-Dried Powders of a Recombinant Humanized Anti-IgE Monoclonal Antibody1

Steven J. Shire, Chung C. Hsu, Y. Maa, 1999, Pharmaceutical Research.

The Stability of Recombinant Human Growth Hormone in Poly(lactic-co-glycolic acid) (PLGA) Microspheres

Brooks M. Boyd, Chung C. Hsu, V. Mukku, 1997, Pharmaceutical Research.

Less-painful emulsion formulations for intravenous administration of clarithromycin

Chung C. Hsu, J. Cannon, H. Hui, 1994 .

Application of frequency-modulated spectroscopy in vacuum seal integrity testing of lyophilized biological products.

Chung C. Hsu, T. Patapoff, B. Kabakoff, 2004, PDA journal of pharmaceutical science and technology.

Membrane fouling in sterile filtration of recombinant human growth hormone

Chung C. Hsu, Y. Maa, 1996, Biotechnology and bioengineering.

Recombinant human growth hormone poly(lactic-co-glycolic acid) (PLGA) microspheres provide a long lasting effect

Brooks M. Boyd, Chung C. Hsu, V. Mukku, 1997 .

Replacing succinate with glycolate buffer improves the stability of lyophilized interferon-γ

Chung C. Hsu, H. Costantino, T. Nguyen, 1996 .

Spray Dried Powders and Powder Blends of Recombinant Human Deoxyribonuclease (rhDNase) for Aerosol Delivery

Chung C. Hsu, H. Chan, M. Mumenthaler, 1997, Pharmaceutical Research.

Surface Denaturation at Solid-Void Interface—A Possible Pathway by Which Opalescent Participates Form During the Storage of Lyophilized Tissue-Type Plasminogen Activator at High Temperatures

Chung C. Hsu, G. Koe, D. Yeung, 2004, Pharmaceutical Research.

Liquid-liquid emulsification by rotor/stator homogenization

Chung C. Hsu, Y. Maa, 1996 .

Effect of high shear on proteins

Chung C. Hsu, Y. Maa, Yuh‐Fun Maa, 2000, Biotechnology and bioengineering.

Spray-coating of rhDNase on lactose: Effect of system design, operational parameters and protein formulation

Chung C. Hsu, Y. Maa, P. Nguyen, 1996 .

Raman spectroscopic characterization of drying-induced structural changes in a therapeutic antibody: correlating structural changes with long-term stability.

Rita L. Wong, Chung C. Hsu, Samir U Sane, 2004, Journal of pharmaceutical sciences.

Industrial scale harvest of proteins from mammalian cell culture by tangential flow filtration

S E Builder, Chung C. Hsu, R. van Reis, 1991, Biotechnology and bioengineering.

Aggregation of recombinant human growth hormone induced by phenolic compounds

Chung C. Hsu, Y. Maa, 1996 .

Water sorption behavior of lyophilized protein–sugar systems and implications for solid-state interactions

Chung C. Hsu, H. Costantino, S. Wu, 1998 .

Fourier‐transform Infrared Spectroscopic Analysis of the Secondary Structure of Recombinant Humanized Immunoglobulin G

Chung C. Hsu, S. Shire, H. Costantino, 1997 .

Investigating Liquid Leak from Pre-Filled Syringes upon Needle Shield Removal: Effect of Air Bubble Pressure

Chung C. Hsu, Y. Maa, D. Overcashier, 2011, PDA Journal of Pharmaceutical Science and Technology.

Fourier‐transform Infrared Spectroscopic Investigation of the Secondary Structure of Aqueous and Dried Recombinant Human Deoxyribonuclease I

Chung C. Hsu, K. Griebenow, S. Shire, 1998 .

Determination of residual moisture in lyophilized protein pharmaceuticals using a rapid and non-invasive method: near infrared spectroscopy.

Chung C. Hsu, Chung C Hsu, Tanya P Lin, 2002, PDA journal of pharmaceutical science and technology.

Fourier‐transform Infrared Spectroscopy Demonstrates that Lyophilization Alters the Secondary Structure of Recombinant Human Growth Hormone

Chung C. Hsu, H. Costantino, T. Nguyen, 1996 .

A specific molar ratio of stabilizer to protein is required for storage stability of a lyophilized monoclonal antibody.

J L Cleland, Chung C. Hsu, J. Carpenter, 2001, Journal of pharmaceutical sciences.

The effect of sugars and buffer excipients on the stabilization of a lyophilized formulation for an anti-IgE humanized monoclonal antibody

Chung C. Hsu, S. Shire, J. Andya, 1996 .

Effect of Moisture on the Stability of a Lyophilized Humanized Monoclonal Antibody Formulation

Chung C. Hsu, C. Hsu, S. Shire, 2001, Pharmaceutical Research.

Protein denaturation by combined effect of shear and air-liquid interface.

Chung C. Hsu, Y. Maa, C. Hsu, 1997, Biotechnology and bioengineering.

Determining the optimum residual moisture in lyophilized protein pharmaceuticals.

Chung C. Hsu, C. A. Ward, C. Hsu, 1992, Developments in biological standardization.

Effect of mannitol crystallization on the stability and aerosol performance of a spray-dried pharmaceutical protein, recombinant humanized anti-IgE monoclonal antibody.

Chung C. Hsu, Y. Maa, C. Hsu, 1998, Journal of pharmaceutical sciences.