Francois Pognan

发表

Ensuring confidence in predictions: A scheme to assess the scientific validity of in silico models.

Thomas Steger-Hartmann, Manuel Pastor, Mark T D Cronin, 2015, Advanced drug delivery reviews.

Improving the Safety Assessment of Chemicals and Drug Candidates by the Integration of Bioinformatics and Chemoinformatics Data.

Thomas Steger-Hartmann, Francois Pognan, F. Pognan, 2018, Basic & clinical pharmacology & toxicology.

Bile acids in drug induced liver injury: Key players and surrogate markers.

Michael Merz, Francois Pognan, F. Pognan, 2016, Clinics and research in hepatology and gastroenterology.

Validation and development of fluorescence two‐dimensional differential gel electrophoresis proteomics technology

Matthew Davison, Robert Tonge, Edward Hawkins, 2001, Proteomics.

Imatinib does not induce cardiotoxicity at clinically relevant concentrations in preclinical studies.

Estelle Marrer, Philippe Couttet, Danielle Roman, 2010, Leukemia research.

In silico prediction of in vivo toxicities (eTox)—The Innovative Medicines Initiative Approach☆

Ferran Sanz, Thomas Steger-Hartmann, Francois Pognan, 2009 .

An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy.

John C Lindon, Jeremy K Nicholson, Muireann Coen, 2003, Chemical research in toxicology.

Determination of liver specific toxicities in rat hepatocytes by high content imaging during 2-week multiple treatment.

Marianne Uteng, Francois Pognan, F. Pognan, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Genomics, proteomics and metabonomics in toxicology: hopefully not 'fashionomics'.

Francois Pognan, F. Pognan, 2004, Pharmacogenomics.

Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans

Philip Hewitt, Richard J Weaver, Yvonne Will, 2016, BioMed research international.

Detection, Elimination, Mitigation, and Prediction of Drug-Induced Liver Injury in Drug Discovery

Francois Pognan, F. Pognan, 2018 .

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation.

Francois Pognan, F. Pognan, B. Greenberg, 2004, Toxicological sciences : an official journal of the Society of Toxicology.

High Content Imaging Approaches for In Vitro Toxicology

Marianne Uteng, Francois Pognan, F. Pognan, 2014 .

Investigative safety science as a competitive advantage for Pharma

David J Heard, Michael Merz, Pierre Moulin, 2012, Expert opinion on drug metabolism & toxicology.