Alison J. Foster

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Development of an automated, high-throughput hepatocyte spheroid screen for use within the pharmaceutical industry

Dominic P. Williams, Alison J. Foster, C. Sefton, 2016 .

Evaluation of the use of imaging parameters for the detection of compound-induced hepatotoxicity in 384-well cultures of HepG2 cells and cryopreserved primary human hepatocytes.

Alison J. Foster, J. G. Kenna, H. Garside, 2014, Toxicology in vitro : an international journal published in association with BIBRA.

Predicting Drug-Induced Liver Injury with Bayesian Machine Learning.

Alison J. Foster, Dominic P. Williams, S. Lazic, 2019, Chemical research in toxicology.

A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.

Matthew H Bridgland-Taylor, Alison J Foster, Alison J. Foster, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Glutathione metabolism modeling: a mechanism for liver drug-robustness and a new biomarker strategy.

Alison J. Foster, H. Westerhoff, J. Snoep, 2013, Biochimica et biophysica acta.

In vitro approach to assess the potential for risk of idiosyncratic adverse reactions caused by candidate drugs.

Yan Li, Hugues Dolgos, R. A. Thompson, 2012, Chemical research in toxicology.

Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury

Simon Messner, Alison J. Foster, Brian Middleton, 2017, Archives of Toxicology.

The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds.

Alison J. Foster, Dominic P. Williams, J. Rahnenführer, 2021, Chemico-biological interactions.

Improved hepatic physiology in hepatic cytochrome P450 reductase null (HRN™) mice dosed orally with fenclozic acid.

Alison J. Foster, I. Wilson, J. G. Kenna, 2017, Toxicology research.

Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild-type mice

Alison J. Foster, I. Wilson, J. G. Kenna, 2016, Archives of Toxicology.

Microsoft Word-58424088-file00.docx

Alison J. Foster, J. G. Kenna, C. Elmore, 2014 .

Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild-type mice

Alison J. Foster, I. Wilson, J. G. Kenna, 2016, Archives of Toxicology.

Introducing an automated high content confocal imaging approach for Organs-on-Chips.

Samantha Peel, Geraldine A Hamilton, Kyung-Jin Jang, 2019, Lab on a chip.

Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid

Alison J. Foster, Dominic P. Williams, S. Lazic, 2019, Archives of Toxicology.

Characterization of THLE-Cytochrome P450 (P450) Cell Lines: Gene Expression Background and Relationship to P450-Enzyme Activity

Marie M. Ahlström, Alison J. Foster, J. G. Kenna, 2012, Drug Metabolism and Disposition.

Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study

Frank Jacobs, Volker M Lauschke, Jan Snoeys, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Multiple Compound-Related Adverse Properties Contribute to Liver Injury Caused by Endothelin Receptor Antagonists

R. A. Thompson, Alison J. Foster, J. G. Kenna, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Cytotoxicity evaluation using cryopreserved primary human hepatocytes in various culture formats.

Alison J. Foster, Dominic P. Williams, A. Czich, 2016, Toxicology letters.

Bioactivation of the cannabinoid receptor antagonist rimonabant to a cytotoxic iminium ion metabolite.

Alison J. Foster, J. G. Kenna, D. Temesi, 2013, Chemical research in toxicology.

Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid

Alison J. Foster, Dominic P. Williams, S. Lazic, 2019, Archives of Toxicology.

A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.

Alison J. Foster, J. G. Kenna, Frida S. Gustafsson, 2014, Toxicological sciences : an official journal of the Society of Toxicology.