Helmut Segner

发表

Expert opinion on toxicity profiling—report from a NORMAN expert group meeting

Timo Hamers, Juliette Legler, Ludek Blaha, 2013, Integrated environmental assessment and management.

Establish a database format for alternative toxicity assays

Helmut Segner, Mark T. D. Cronin, Ronny Blust, 2007 .

The SOLUTIONS project: challenges and responses for present and future emerging pollutants in land and water resources management.

Helmut Segner, Thomas Backhaus, Rolf Altenburger, 2015, The Science of the total environment.

Monitoring Programmes, Multiple Stress Analysis and Decision Support for River Basin Management

Helmut Segner, Antonio Marcomini, Werner Brack, 2014 .

Data quality assessment for in silico methods: A survey of approaches and needs

Helmut Segner, Judith C. Madden, Silke Gabbert, 2010 .

Guidance on the use of toxicogenomics as input in ITS

Helmut Segner, Dries Knapen, Lucia Vergauwen, 2011 .

Optimizing the aquatic toxicity assessment under REACH through an integrated testing strategy (ITS).

Helmut Segner, Emilio Benfenati, Anna Lombardo, 2014, Environmental research.

Integrated testing strategy (ITS) for bioaccumulation assessment under REACH.

Helmut Segner, Ralph Kühne, Antonio Franco, 2014, Environment international.

Future water quality monitoring--adapting tools to deal with mixtures of pollutants in water resource management.

Helmut Segner, Thomas Backhaus, Rolf Altenburger, 2015, The Science of the total environment.

Project Fishnet: A balance between analysis and synthesis

Helmut Segner, Armin Peter, Patricia Burkhardt-Holm, 2002 .

Immunotoxic effects of environmental toxicants in fish — how to assess them?

Helmut Segner, H. Segner, B. Köllner, 2012, Environmental Science and Pollution Research.

Isolation and primary culture of teleost hepatocytes

Helmut Segner, H. Segner, 1998 .

Moving beyond a descriptive aquatic toxicology: the value of biological process and trait information.

Helmut Segner, H. Segner, 2011, Aquatic toxicology.

MEIC Evaluation of acute systemic toxicity. Part VII. Prediction of human toxicity by results from testing of the first 30 reference chemicals with 27 further In Vitro assays

Helmut Segner, M. Cottin, A. Thuvander, 2000 .

The state of in vitro science for use in bioaccumulation assessments for fish

Helmut Segner, Anne V Weisbrod, Mark Bonnell, 2009, Environmental toxicology and chemistry.

MEIC Evaluation of Acute Systemic Toxicity

Helmut Segner, Koichi Imai, Tadao Ohno, 1998 .

MODELKEY : Key findings and recommendations for reaching the EU Water Framework Directive’s quality objectives (EU PROJECTS)

Helmut Segner, Werner Brack, Antonio Marcomini, 2010 .

Status and Causal Pathway Assessments Supporting River Basin Management

Markus A. Wetzel, Helmut Segner, Willem Goedkoop, 2014 .

Assessment of fish health status in four Swiss rivers showing a decline of brown trout catches

Helmut Segner, Daniel Bernet, Patricia Burkhardt-Holm, 2007, Aquatic Sciences.

Toward sustainable environmental quality: Priority research questions for Europe

Helmut Segner, Thomas Backhaus, Marco Vighi, 2018, Environmental toxicology and chemistry.

Use of In Vitro Absorption, Distribution, Metabolism, and Excretion (ADME) Data in Bioaccumulation Assessments for Fish

Helmut Segner, Karluss Thomas, Irvin R. Schultz, 2007 .

Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish.

Helmut Segner, Olivier Kah, Rik I L Eggen, 2008, General and comparative endocrinology.

An environmentally relevant concentration of estrogen induces arrest of male gonad development in zebrafish, Danio rerio

Helmut Segner, Christoph Schäfers, Gerd Maack, 2005, Environmental toxicology and chemistry.

Multivariate mode-of-action analysis of acute toxicity of phenols

Helmut Segner, Gerrit Schüürmann, G. Schüürmann, 1997 .

Fixed‐effect‐level toxicity equivalents—a suitable parameter for assessing ethoxyresorufin‐O‐deethylase induction potency in complex environmental samples

Helmut Segner, Werner Brack, Gerrit Schüürmann, 2000 .

Vitellogenin synthesis in primary cultures of fish liver cells as endpoint for in vitro screening of the (anti)estrogenic activity of chemical substances.

Helmut Segner, H. Segner, J. M. Navas, 2006, Aquatic toxicology.

Variability of in vivo fish acute toxicity data.

Helmut Segner, Sonja Jeram, H. Segner, 2009, Regulatory toxicology and pharmacology : RTP.

Morphological development of the gonads in zebrafish

Helmut Segner, Gerd Maack, H. Segner, 2003 .

Effects of prochloraz and nonylphenol diethoxylate on hepatic biotransformation enzymes in trout: a comparative in vitro/in vivo-assessment using cultured hepatocytes.

Helmut Segner, J. Cravedi, H. Segner, 2001, Aquatic toxicology.

The potential of mechanism-based bioanalytical tools in ecotoxicological exposure and effect assessment

Helmut Segner, H. Segner, R. Eggen, 2003, Analytical and bioanalytical chemistry.

Establishing Causality between Pollution and Effects at Different Levels of Biological Organization: The VALIMAR Project

Helmut Segner, Uwe Dietze, Thomas Braunbeck, 2003 .

Towards science-based sediment quality standards-Effects of field-collected sediments in rainbow trout (Oncorhynchus mykiss).

Helmut Segner, Henner Hollert, Lisa Baumann, 2015, Aquatic toxicology.

Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence.

Igor Linkov, Helmut Segner, Stephen W. Edwards, 2015, Regulatory toxicology and pharmacology : RTP.

Assessing the ecological impact of chemical pollution on aquatic ecosystems requires the systematic exploration and evaluation of four lines of evidence

Helmut Segner, Thomas Backhaus, Werner Brack, 2019, Environmental Sciences Europe.

Where Have All the FISH Gone

Helmut Segner, Walter Giger, Armin Peter, 2005 .

The use of Fish Cells in Ecotoxicology: The Report and Recommendations of ECVAM Workshop 471, 2

Helmut Segner, Thomas Braunbeck, Chris Wood, 2003, Alternatives to laboratory animals : ATLA.

Let us empower the WFD to prevent risks of chemical pollution in European rivers and lakes

Helmut Segner, Rolf Altenburger, Jaroslav Slobodnik, 2019, Environmental Sciences Europe.

Characterization of the estrogenicity of Swiss midland rivers using a recombinant yeast bioassay and plasma vitellogenin concentrations in feral male brown trout

Helmut Segner, Armin Peter, Patricia Burkhardt-Holm, 2005, Environmental toxicology and chemistry.

MEIC Evaluation of Acute Systemic Toxicity

Helmut Segner, Tadao Ohno, Sirpa Kärenlampi, 1998 .

The use of Mechanisms and Modes of Toxic Action in Integrated Testing Strategies: The Report and Recommendations of a Workshop held as part of the European Union OSIRIS Integrated Project

Helmut Segner, Romualdo Benigni, Dik van de Meent, 2009, Alternatives to laboratory animals : ATLA.

The project VALIMAR (VALIdation of bioMARkers for the assessment of small stream pollution): objectives, experimental design, summary of results, and recommendations for the application of biomarkers in risk assessment

Helmut Segner, Thomas Braunbeck, Gerrit Schüürmann, 2001 .

Chemometric discrimination between streams based on chemical, limnological and biological data taken from freshwater fishes and their interrelationships

Helmut Segner, Uwe Dietze, Thomas Braunbeck, 2001 .