Daniel L Villeneuve

发表

Practical approaches to adverse outcome pathway development and weight‐of‐evidence evaluation as illustrated by ecotoxicological case studies

Kellie A Fay, Daniel L Villeneuve, Carlie A LaLone, 2017, Environmental toxicology and chemistry.

Adverse Outcome Pathways—Organizing Toxicological Information to Improve Decision Making

Yu-Mei Tan, Stephen W. Edwards, Daniel L Villeneuve, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Extracting and Benchmarking Emerging Adverse Outcome Pathway Knowledge

Daniel L Villeneuve, Nathan L Pollesch, Jason M O’Brien, 2019, Toxicological sciences : an official journal of the Society of Toxicology.

High‐throughput screening and environmental risk assessment: State of the science and emerging applications

Cheryl A Murphy, Daniel L Villeneuve, Cheryl A. Murphy, 2018, Environmental toxicology and chemistry.

The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency.

Ann M Richard, Imran Shah, Thomas B Knudsen, 2019, Toxicological sciences : an official journal of the Society of Toxicology.

Adverse outcome pathway development II: best practices.

Sharon Munn, Brigitte Landesmann, Daniel L Villeneuve, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Adverse outcome pathway (AOP) development I: strategies and principles.

Sharon Munn, Brigitte Landesmann, Daniel L Villeneuve, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

Daniel L Villeneuve, Gerald T Ankley, Richard S Bennett, 2010, Environmental toxicology and chemistry.

Adverse outcome pathway networks I: Development and applications

Sharon Munn, Nathan Pollesch, Daniel L Villeneuve, 2018, Environmental toxicology and chemistry.

Adverse outcome pathway networks II: Network analytics

Sharon Munn, Daniel L Villeneuve, Dries Knapen, 2018, Environmental toxicology and chemistry.

Effects of a 3beta-hydroxysteroid dehydrogenase inhibitor, trilostane, on the fathead minnow reproductive axis.

Daniel L Villeneuve, Gerald T Ankley, Dalma Martinovic, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Ketoconazole in the fathead minnow (Pimephales promelas): Reproductive toxicity and biological compensation

Daniel L Villeneuve, Gerald T Ankley, G. Ankley, 2007, Environmental toxicology and chemistry.

Linkage of biochemical responses to population‐level effects: A case study with vitellogenin in the fathead minnow (Pimephales promelas)

Daniel L Villeneuve, Gerald T Ankley, David H. Miller, 2007, Environmental toxicology and chemistry.

Effects of the insecticide fipronil on reproductive endocrinology in the fathead minnow

Daniel L Villeneuve, Gerald T Ankley, David C Bencic, 2013, Environmental toxicology and chemistry.

Temporal changes in biological responses and uncertainty in assessing risks of endocrine-disrupting chemicals: insights from intensive time-course studies with fish.

Daniel L Villeneuve, Gerald T Ankley, G. Ankley, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

Reproductive responses of common carp (Cyprinus carpio) exposed in cages to influent of the Las Vegas Wash in Lake Mead, Nevada, from late winter to early spring.

Daniel L Villeneuve, Erin M. Snyder, John P Giesy, 2004, Environmental science & technology.

A graphical systems model and tissue-specific functional gene sets to aid transcriptomic analysis of chemical impacts on the female teleost reproductive axis.

Stephen W. Edwards, Daniel L Villeneuve, Gerald T Ankley, 2012, Mutation research.

Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part I: Fathead minnow.

Daniel L Villeneuve, Gerald T Ankley, Dries Knapen, 2016, Aquatic toxicology.

Expression signatures for a model androgen and antiandrogen in the fathead minnow (Pimephales promelas) ovary.

Daniel L Villeneuve, Gerald T Ankley, Nancy D Denslow, 2009, Environmental science & technology.

A Reduced Transcriptome Approach to Assess Environmental Toxicants Using Zebrafish Embryo Test.

Wei Shi, Daniel L Villeneuve, Xiaowei Zhang, 2018, Environmental science & technology.

Perturbation of gene expression and steroidogenesis with in vitro exposure of fathead minnow ovaries to ketoconazole.

Daniel L Villeneuve, Gerald T Ankley, Nancy D Denslow, 2008, Marine environmental research.

An "EAR" on Environmental Surveillance and Monitoring: A Case Study on the Use of Exposure-Activity Ratios (EARs) to Prioritize Sites, Chemicals, and Bioactivities of Concern in Great Lakes Waters.

Daniel L Villeneuve, Gerald T Ankley, Richard S Judson, 2017, Environmental science & technology.

In Response: The path forward for the adverse outcome pathway framework—A regulatory perspective

Daniel L Villeneuve, D. Villeneuve, 2015, Environmental toxicology and chemistry.

Cross‐species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone

Daniel L Villeneuve, Carlie A LaLone, Gerald T Ankley, 2013, Environmental toxicology and chemistry.

Relationship between brain and ovary aromatase activity and isoform-specific aromatase mRNA expression in the fathead minnow (Pimephales promelas).

Daniel L Villeneuve, Gerald T Ankley, G. Ankley, 2006, Aquatic toxicology.

Developing predictive approaches to characterize adaptive responses of the reproductive endocrine axis to aromatase inhibition: I. Data generation in a small fish model.

Daniel L Villeneuve, Gerald T Ankley, Leah C. Wehmas, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part II: Zebrafish.

Hilda Witters, Daniel L Villeneuve, Gerald T Ankley, 2016, Aquatic toxicology.

Transcription of key genes regulating gonadal steroidogenesis in control and ketoconazole- or vinclozolin-exposed fathead minnows.

Daniel L Villeneuve, Gerald T Ankley, Dalma Martinovic, 2007, Toxicological sciences : an official journal of the Society of Toxicology.

Gene expression responses in male fathead minnows exposed to binary mixtures of an estrogen and antiestrogen

Daniel L Villeneuve, Gerald T Ankley, Nancy D Denslow, 2009, BMC Genomics.

Relationship of plasma sex steroid concentrations in female fathead minnows to reproductive success and population status.

Daniel L Villeneuve, Gerald T Ankley, David H. Miller, 2008, Aquatic toxicology.

Vision & strategy: Predictive ecotoxicology in the 21st century

Daniel L Villeneuve, Natàlia Garcia-Reyero, N. Garcia-Reyero, 2011, Environmental toxicology and chemistry.

Evaluation of the scientific underpinnings for identifying estrogenic chemicals in nonmammalian taxa using mammalian test systems

Daniel L Villeneuve, Carlie A LaLone, Gerald T Ankley, 2016, Environmental toxicology and chemistry.

Effects of a glucocorticoid receptor agonist, dexamethasone, on fathead minnow reproduction, growth, and development

Daniel L Villeneuve, Carlie A LaLone, Gerald T Ankley, 2012, Environmental toxicology and chemistry.

Prioritization of pharmaceuticals for potential environmental hazard through leveraging a large‐scale mammalian pharmacological dataset

Daniel L Villeneuve, Carlie A LaLone, Gerald T Ankley, 2016, Environmental toxicology and chemistry.

Computational model of the fathead minnow hypothalamic-pituitary-gonadal axis: Incorporating protein synthesis in improving predictability of responses to endocrine active chemicals.

Daniel L Villeneuve, Gerald T Ankley, Rory B Conolly, 2016, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

Comparison of fathead minnow ovary explant and H295R cell-based steroidogenesis assays for identifying endocrine-active chemicals.

Daniel L Villeneuve, Gerald T Ankley, John L Newsted, 2007, Ecotoxicology and environmental safety.

Quantitative proteomic profiles of androgen receptor signaling in the liver of fathead minnows (Pimephales promelas).

Daniel L Villeneuve, Gerald T Ankley, Christopher J Martyniuk, 2009, Journal of proteome research.

Weight of evidence evaluation of a network of adverse outcome pathways linking activation of the nicotinic acetylcholine receptor in honey bees to colony death.

Daniel L Villeneuve, Carlie A LaLone, Gerald T Ankley, 2017, The Science of the total environment.

A graphical systems model to facilitate hypothesis-driven ecotoxicogenomics research on the teleost brain-pituitary-gonadal axis.

Daniel L Villeneuve, Gerald T Ankley, Nancy D Denslow, 2007, Environmental science & technology.

The fathead minnow in aquatic toxicology: past, present and future.

Daniel L Villeneuve, Gerald T Ankley, G. Ankley, 2006, Aquatic toxicology.

Editor's Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A Web-Based Tool for Addressing the Challenges of Cross-Species Extrapolation of Chemical Toxicity.

Daniel L Villeneuve, Carlie A LaLone, Gerald T Ankley, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Editor's Highlight: Computational Modeling of Plasma Vitellogenin Alterations in Response to Aromatase Inhibition in Fathead Minnows.

Rory Conolly, Daniel L Villeneuve, Gerald T Ankley, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Linking field‐based metabolomics and chemical analyses to prioritize contaminants of emerging concern in the Great Lakes basin

Daniel L Villeneuve, Gerald T Ankley, Timothy W Collette, 2016, Environmental toxicology and chemistry.

Integrated assessment of runoff from livestock farming operations: Analytical chemistry, in vitro bioassays, and in vivo fish exposures

Daniel L Villeneuve, Carlie A LaLone, Gerald T Ankley, 2014, Environmental toxicology and chemistry.

Evidence for Cross Species Extrapolation of Mammalian-Based High-Throughput Screening Assay Results.

Daniel L Villeneuve, Carlie A LaLone, Gerald T Ankley, 2018, Environmental science & technology.

A computational model of the hypothalamic-pituitary-gonadal axis in male fathead minnows exposed to 17alpha-ethinylestradiol and 17beta-estradiol.

Daniel L Villeneuve, Gerald T Ankley, Nancy D Denslow, 2009, Toxicological Sciences.

Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence.

Igor Linkov, Helmut Segner, Stephen W. Edwards, 2015, Regulatory toxicology and pharmacology : RTP.

Use of gene expression, biochemical and metabolite profiles to enhance exposure and effects assessment of the model androgen 17β-trenbolone in fish.

Daniel L Villeneuve, Gerald T Ankley, Timothy W Collette, 2011, Environmental toxicology and chemistry.

Environmental surveillance and monitoring—The next frontiers for high‐throughput toxicology

Daniel L Villeneuve, Gerald T Ankley, Keith A Houck, 2016, Environmental toxicology and chemistry.

Impaired swim bladder inflation in early life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid

Kellie A Fay, Daniel L Villeneuve, Gerald T Ankley, 2017, Environmental toxicology and chemistry.

Ecdysone Receptor Agonism Leading to Lethal Molting Disruption in Arthropods: Review and Adverse Outcome Pathway Development.

Daniel L Villeneuve, You Song, Knut Erik Tollefsen, 2017, Environmental science & technology.

Evaluation of the methoxytriazine herbicide prometon using a short‐term fathead minnow reproduction test and a suite of in vitro bioassays

Daniel L Villeneuve, Gerald T Ankley, John P Giesy, 2006, Environmental toxicology and chemistry.

Endocrine disrupting chemicals in fish: developing exposure indicators and predictive models of effects based on mechanism of action.

Stephen W. Edwards, Rong-Lin Wang, Daniel L Villeneuve, 2009, Aquatic toxicology.

Reproductive toxicity of vinclozolin in the fathead minnow: Confirming an anti‐androgenic mode of action

Daniel L Villeneuve, Gerald T Ankley, Dalma Martinović, 2008, Environmental toxicology and chemistry.