Thijs J. Hagenbeek

发表

Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes

David K. Finlay, Linda V. Sinclair, Carmen Feijoo, 2009, The Journal of experimental medicine.

PlGF Blockade Does Not Inhibit Angiogenesis during Primary Tumor Growth

Thijs J. Hagenbeek, M. Shibuya, I. Kasman, 2010, Cell.

Machine-Learning and Chemicogenomics Approach Defines and Predicts Cross-Talk of Hippo and MAPK Pathways

Thijs J. Hagenbeek, Mamie Yu, Z. Modrušan, 2021 .

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

Thijs J. Hagenbeek, N. van Bruggen, F. Peale, 2010, Proceedings of the National Academy of Sciences.

The metabolic perturbators metformin, phenformin and AICAR interfere with the growth and survival of murine PTEN-deficient T cell lymphomas and human T-ALL/T-LL cancer cells.

Thijs J. Hagenbeek, I. Ben-Sahra, F. Bost, 2013, Cancer letters.

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

David K. Finlay, Linda V. Sinclair, Thijs J. Hagenbeek, 2008, Nature Immunology.

Therapeutic antibody targeting of individual Notch receptors

Thijs J. Hagenbeek, J. Zha, J. Ridgway, 2010, Nature.

Constitutive NOTCH3 Signaling Promotes the Growth of Basal Breast Cancers.

Matthew J. Brauer, Thijs J. Hagenbeek, M. Brauer, 2017, Cancer research.

The Loss of PTEN Allows TCR αβ Lineage Thymocytes to Bypass IL-7 and Pre-TCR–mediated Signaling

Thijs J. Hagenbeek, J. Trapman, J. Nunès, 2004, The Journal of experimental medicine.

The Tumor Suppressor BAP1 Regulates the Hippo Pathway in Pancreatic Ductal Adenocarcinoma

Thijs J. Hagenbeek, Matthew T. Chang, J. Eastham‐Anderson, 2020, Cancer Research.

Pharmacological inhibition of carbonic anhydrase XII interferes with cell proliferation and induces cell apoptosis in T-cell lymphomas.

Thijs J. Hagenbeek, C. Supuran, V. Imbert, 2013, Cancer letters.

The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors

Thijs J. Hagenbeek, Matthew T. Chang, G. Hatzivassiliou, 2018, Science Signaling.

Phosphoinositide 3-kinase (PI3K) and nutrient sensing mTOR (mammalian target of rapamycin) pathways control T lymphocyte trafficking

Ager, Thijs J. Hagenbeek, K. Okkenhaug, 2011 .

An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance

Thijs J. Hagenbeek, P. Beroza, Hoai An Le Thi, 2023, Nature Cancer.

Hippo pathway dysregulation occurs in multiple cancers through genetic and non-genetic alterations resulting in translocation of YAP to the nucleus and activation of the TEAD family of transcription

Zora, Thijs J. Hagenbeek, Mamie Yu, 2020 .

Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes

Thijs J. Hagenbeek, Steve Lianoglou, S. Rutz, 2018, Science Immunology.

Murine Pten(-/-) T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and γc/TCR signals for thymic exit.

Thijs J. Hagenbeek, S. Seshagiri, J. Stinson, 2014, Cancer letters.

The Loss of PTEN Allows TCR (cid:1)(cid:2) Lineage Thymocytes to Bypass IL-7 and Pre-TCR–mediated Signaling

Thijs J. Hagenbeek, J. Trapman, J. Nunès, 2004 .

T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus

Thijs J. Hagenbeek, H. Spits, T. Hagenbeek, 2008, Leukemia.

Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation

Thijs J. Hagenbeek, Z. Modrušan, I. Wertz, 2023, bioRxiv.

Machine learning and chemico-genomics approach defines and predicts cross-talk of Hippo and MAPK pathways.

Thijs J. Hagenbeek, Mamie Yu, Z. Modrušan, 2020, Cancer discovery.

L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia

Thijs J. Hagenbeek, V. Imbert, J. Peyron, 2014, Leukemia.

The Loss of PTEN Allows TCR αβ Lineage Thymocytes to Bypass IL-7 and Pre-TCR–mediated Signaling

Thijs J. Hagenbeek, J. Trapman, J. Nunès, 2004, The Journal of experimental medicine.

Inaugural Article: Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

Thijs J. Hagenbeek, F. Peale, Z. Modrušan, 2010 .

The metabolic perturbators metformin, phenformin and AICAR interfere with the growth and survival of murine PTEN-deficient T cell lymphomas and human T-ALL/T-LL cancer cells.

Thijs J. Hagenbeek, I. Ben-Sahra, F. Bost, 2013, Cancer letters.