Jaclyn K. Mann

发表

The Fitness Landscape of HIV-1 Gag: Advanced Modeling Approaches and Validation of Model Predictions by In Vitro Testing

John P. Barton, Andrew L. Ferguson, Bruce D. Walker, 2014, PLoS Comput. Biol..

Translating HIV sequences into quantitative fitness landscapes predicts viral vulnerabilities for rational immunogen design.

Andrew L. Ferguson, Jaclyn K. Mann, B. Walker, 2013, Immunity.

SUPPORTING INFORMATION FOR The Fitness Landscape of HIV-1 Gag

Jaclyn K. Mann, B. Walker, A. Chakraborty, 2014 .

Intersubtype Differences in the Effect of a Rare p24 Gag Mutation on HIV-1 Replicative Fitness

Jaclyn K. Mann, F. Pereyra, T. Miura, 2012, Journal of Virology.

Attenuated HIV-1 Nef But Not Vpu Function in a Cohort of Rwandan Long-Term Survivors

Jaclyn K. Mann, G. Umviligihozo, E. Karita, 2022, Frontiers in Virology.

An HIV-1 Nef genotype that diminishes immune control mediated by protective human leucocyte antigen alleles.

Jaclyn K. Mann, T. Ndung’u, M. Mori, 2020, AIDS.

Modelling and in vitro testing of the HIV-1 Nef fitness landscape

Jaclyn K. Mann, A. Chakraborty, T. Ndung’u, 2019, Virus evolution.

Vulnerable targets in HIV-1 Pol for attenuation-based vaccine design.

Jaclyn K. Mann, T. Ndung’u, P. Madlala, 2020, Virology.

HIV-1 evades a gag mutation that abrogates KIR binding and disinhibits NK cells in infected individuals with KIR2DL2+/HLA-C*03: 04+ genotype.

Jaclyn K. Mann, M. Altfeld, T. Ndung’u, 2020, AIDS.

FULL TITLE: HIV-1 Evades a Gag Mutation that Abrogates KIR Binding and Disinhibits NK Cells in Infected Individuals with KIR2DL2/HLA-C*03:04 Genotype SHORT TITLE: HIV-1 clade C avoids KIR2DL2 binding

Jaclyn K. Mann, M. Altfeld, T. Ndung’u, 2020 .

Gag mutation that abrogates killer cell immunoglobulin-like receptor binding and disinhibits natural killer cells in infected individuals with KIR 2 DL 2 R / HLA-C M 03 : 04 R genotype

Jaclyn K. Mann, M. Altfeld, T. Ndung’u, 2020 .

No Evidence for Selection of HIV-1 with Enhanced Gag-Protease or Nef Function among Breakthrough Infections in the CAPRISA 004 Tenofovir Microbicide Trial

Jaclyn K. Mann, S. Omarjee, T. Ndung’u, 2013, PloS one.

HIV-1 persistence in lymph node T follicular helper cells (TFH) is mitigated by functional virus-specific T cell responses during hyperacute-treated HIV-1 infection

Jaclyn K. Mann, B. Walker, T. Ndung’u, 2021 .

HIV-1 vaccine immunogen design strategies

Jaclyn K. Mann, T. Ndung’u, J. Mann, 2015, Virology Journal.

The potential of lactoferrin, ovotransferrin and lysozyme as antiviral and immune-modulating agents in COVID-19

Jaclyn K. Mann, T. Ndung’u, J. Mann, 2020, Future Virology.

Mother-to-Child HIV Transmission Bottleneck Selects for Consensus Virus with Lower Gag-Protease-Driven Replication Capacity

Jaclyn K. Mann, T. Ndung’u, P. Goulder, 2017, Journal of Virology.

Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa

Jaclyn K. Mann, M. Altfeld, M. Carrington, 2015, PLoS medicine.

Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence

Angela R. McLean, John Frater, Jonathan M. Carlson, 2014, Proceedings of the National Academy of Sciences.

Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression

Jaclyn K. Mann, T. Ndung’u, Jeffrey N. Martin, 2017, Journal of Virology.

Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection

Jaclyn K. Mann, T. Ndung’u, Z. Brumme, 2018, Journal of Virology.

Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals

Jaclyn K. Mann, T. Ndung’u, Jeffrey N. Martin, 2017, Journal of Virology.

High Frequency of Transmitted HIV-1 Gag HLA Class I-Driven Immune Escape Variants but Minimal Immune Selection over the First Year of Clade C Infection

Jaclyn K. Mann, B. Walker, T. Ndung’u, 2015, PloS one.

Fitness Replicative Rare p24 Gag Mutation on HIV-1 Intersubtype Differences in the Effect of a

Jaclyn K. Mann, T. Miura, B. Walker, 2014 .

Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure.

Jaclyn K. Mann, B. Walker, S. Omarjee, 2014, Virology.

Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5

Jaclyn K. Mann, T. Ndung’u, D. Bangsberg, 2020, PLoS pathogens.

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes

Rosemary M. McCloskey, Jaclyn K. Mann, B. Walker, 2013, Retrovirology.

Title Ability of HIV-1 Nef to downregulate CD 4 and HLA class I differs among viral subtypes Permalink

Rosemary M. McCloskey, Jaclyn K. Mann, B. Walker, 2013 .

Subtle Longitudinal Alterations in Env Sequence Potentiate Differences in Sensitivity to Broadly Neutralizing Antibodies following Acute HIV-1 Subtype C Infection

Jaclyn K. Mann, T. Ndung’u, Z. Ndhlovu, 2022, Journal of virology.

Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa

Jaclyn K. Mann, T. Ndung’u, J. Gilmour, 2021, Retrovirology.

The latest science from the IAS Towards an HIV Cure Symposium

Jaclyn K. Mann, J. Singh, A. Chahroudi, 2016, Journal of virus eradication.

Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants

Jaclyn K. Mann, T. Ndung’u, Z. Ndhlovu, 2018, Nature Communications.

CD8 lymphocytes mitigate HIV-1 persistence in lymph node follicular helper T cells during hyperacute-treated infection

Jaclyn K. Mann, B. Walker, T. Ndung’u, 2022, Nature Communications.

Consequences of HLA‐associated mutations in HIV‐1 subtype C Nef on HLA‐I downregulation ability

Jaclyn K. Mann, T. Ndung’u, M. Brockman, 2020, Journal of medical virology.

Nef-mediated inhibition of NFAT following TCR stimulation differs between HIV-1 subtypes.

Jaclyn K. Mann, T. Ndung’u, Z. Brumme, 2019, Virology.

Effects of TNF-α and IL-10-819 T>C single nucleotide polymorphisms on urogenital schistosomiasis in preschool children in Zimbabwe

Jaclyn K. Mann, T. Mduluza, A. Vengesai, 2021, African journal of laboratory medicine.

Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection

Jaclyn K. Mann, B. Walker, T. Ndung’u, 2020, BMC Medicine.

Influence of wave action on Mytilus californianus mussel beds

Jaclyn K. Mann, 2011 .

Interleukin-10 and tumour necrosis factor alpha promoter region polymorphisms and susceptibility to urogenital schistosomiasis in young Zimbabwean children living in Schistosoma haematobium endemic regions

Jaclyn K. Mann, T. Mduluza, A. Vengesai, 2020, Southern African journal of infectious diseases.