Stefan Rose-John

发表

TLR4-Dependent Inflammatory Responses IL-6 Trans-Signaling Modulates

Paul J. Hertzog, Matthias Ernst, Brendan J. Jenkins, 2013 .

IL6/sIL6R complex contributes to emergency granulopoietic responses in G-CSF- and GM-CSF-deficient mice.

Antony W Burgess, Matthias Ernst, Stefan Rose-John, 2008, Blood.

Interplay between IFN-γ and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation

Stefan Rose-John, T. S. Wilkinson, S. Rose-John, 2003 .

IL-6 trans-signaling: the heat is on.

Markus F Neurath, Stefan Rose-John, M. Neurath, 2004, Immunity.

Not interferon, but interleukin‐6 controls early gene expression in hepatitis B virus infection

Hildegard Büning, Stefan Rose-John, S. Rose-John, 2009, Hepatology.

ADAM17: a molecular switch to control inflammation and tissue regeneration.

Stefan Rose-John, J. Scheller, A. Chalaris, 2011, Trends in immunology.

Designing cytokine variants by phage-display.

Stefan Rose-John, Heidi Schooltink, 2005, Combinatorial chemistry & high throughput screening.

Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib

Fabian J. Theis, Sebastian Bohl, Ursula Klingmüller, 2017, Front. Physiol..

Structure-guided Optimization of the Interleukin-6 Trans-signaling Antagonist sgp130*

Stefan Rose-John, J. Scheller, A. Chalaris, 2008, Journal of Biological Chemistry.

Virokines in the Pathogenesis of Cancer: Focus on Human Herpesvirus 8

Stefan Rose-John, S. Rose-John, M. Klouche, 2004, Annals of the New York Academy of Sciences.

IL-6 pathway in the liver: From physiopathology to therapy.

Stefan Rose-John, D. Schmidt-Arras, S. Rose-John, 2016, Journal of hepatology.

Abrogation of Viral Interleukin-6 (vIL-6)-Induced Signaling by Intracellular Retention and Neutralization of vIL-6 with an Anti-vIL-6 Single-Chain Antibody Selected by Phage Display

Stefan Rose-John, J. Scheller, S. Rose-John, 2006, Journal of Virology.

The human interleukin‐6 (IL‐6) receptor exists as a preformed dimer in the plasma membrane

Stefan Rose-John, Björn Schuster, S. Rose-John, 2003, FEBS letters.

Dynamics of the gp130 cytokine complex: A model for assembly on the cellular membrane

Stefan Rose-John, S. Rose-John, J. Grötzinger, 2005, Protein science : a publication of the Protein Society.

Trans-Signaling Is a Dominant Mechanism for the Pathogenic Actions of Interleukin-6 in the Brain

Juan Hidalgo, Stefan Rose-John, J. Scheller, 2014, The Journal of Neuroscience.

IL-6 biology: implications for clinical targeting in rheumatic disease

Stefan Rose-John, S. Rose-John, L. Calabrese, 2014, Nature Reviews Rheumatology.

Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer.

Shizuo Akira, Stefan Rose-John, Hana Algül, 2011, Cancer cell.

Viral Interleukin-6: Structure, pathophysiology and strategies of neutralization.

Stefan Rose-John, J. Scheller, S. Rose-John, 2011, European journal of cell biology.

Strawberry notch homolog 2 is a novel inflammatory response factor predominantly but not exclusively expressed by astrocytes in the central nervous system

Stefan Rose-John, S. Rose-John, I. Campbell, 2015, Glia.

RAID3 - An interleukin-6 receptor-binding aptamer with post-selective modification-resistant affinity

Dmitri I Svergun, Martin Zacharias, Ulrich Hahn, 2015, RNA biology.

Elastin-like polypeptides revolutionize recombinant protein expression and their biomedical application.

Stefan Rose-John, Kai Schallau, J. Scheller, 2010, Trends in biotechnology.

Cellular Cholesterol Depletion Triggers Shedding of the Human Interleukin-6 Receptor by ADAM10 and ADAM17 (TACE)*

Stefan Rose-John, S. Rose-John, D. Hartmann, 2003, Journal of Biological Chemistry.

Interleukin-6 biology is coordinated by membrane bound and soluble receptors.

Stefan Rose-John, S. Rose-John, 2003, Acta biochimica Polonica.

Interaction of vascular smooth muscle cells and monocytes by soluble factors synergistically enhances IL-6 and MCP-1 production.

Karl Werdan, Stefan Rose-John, S. Rose-John, 2009, American journal of physiology. Heart and circulatory physiology.

RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction.

Florian Reisinger, Tom Luedde, Matthias Lutz, 2014, Cardiovascular research.

TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling

Stefan Wirtz, Susanne Strand, Peter R. Galle, 2004 .