D W Zaharevitz

Use of 3D QSAR methodology for data mining the National Cancer Institute Repository of Small Molecules: application to HIV-1 reverse transcriptase inhibition.

N Pattabiraman, R Gussio, G E Kellogg, 1998, Methods.

Structure-based design modifications of the paullone molecular scaffold for cyclin-dependent kinase inhibition.

L Meijer, N Pattabiraman, R Gussio, 2000, Anti-cancer drug design.

2-Substituted paullones: CDK1/cyclin B-inhibiting property and in vitro antiproliferative activity.

L Meijer, R Gussio, D W Zaharevitz, 2000, Bioorganic & medicinal chemistry letters.

Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases.

L Meijer, D W Zaharevitz, L. Meijer, 1999, Cancer research.

Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25.

G L Snyder, L Meijer, D W Zaharevitz, 2000, European journal of biochemistry.

Dose-dependent kinetics of all-trans-retinoic acid in rats. Plasma levels and excretion into bile, urine, and faeces.

D W Zaharevitz, M. Sporn, D. Zaharevitz, 1981, Biochemical pharmacology.

The discovery of novel, structurally diverse protein kinase C agonists through computer 3D-database pharmacophore search. Molecular modeling studies.

D W Zaharevitz, S Wang, G W Milne, 1994, Journal of medicinal chemistry.