Kiyohiko Sugano

发表

Strategy in Drug Discovery and Development

Kiyohiko Sugano, 2012 .

Epistemology of Biopharmaceutical Modeling and Good Simulation Practice

Kiyohiko Sugano, 2012 .

Prediction of human intestinal permeability using artificial membrane permeability.

Kiyohiko Sugano, Minoru Machida, M. Machida, 2003, International journal of pharmaceutics.

Aqueous boundary layers related to oral absorption of a drug: from dissolution of a drug to carrier mediated transport and intestinal wall metabolism.

Kiyohiko Sugano, K. Sugano, 2010, Molecular pharmaceutics.

Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid.

Kiyohiko Sugano, Makoto Kataoka, M. Kataoka, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Passive lipoidal diffusion and carrier-mediated cell uptake are both important mechanisms of membrane permeation in drug disposition.

Li Di, Manfred Kansy, Kiyohiko Sugano, 2014, Molecular pharmaceutics.

High throughput solubility measurement with automated polarized light microscopy analysis.

Kiyohiko Sugano, Teruhisa Kato, Takashi Mano, 2006, Journal of pharmaceutical sciences.

Biopharmaceutics Modeling and Simulations: Theory, Practice, Methods, and Applications

Kiyohiko Sugano, 2012 .

Introduction to computational oral absorption simulation

Kiyohiko Sugano, K. Sugano, 2009, Expert opinion on drug metabolism & toxicology.

Physical characterization of meso-erythritol as a crystalline bulking agent for freeze-dried formulations.

Kiyohiko Sugano, Takeshi Yoshino, Y. Yoshihashi, 2015, Chemical & pharmaceutical bulletin.

Correction of Permeability with Pore Radius of Tight Junctions in Caco-2 Monolayers Improves the Prediction of the Dose Fraction of Hydrophilic Drugs Absorbed by Humans

Kiyohiko Sugano, T. Tachibana, Y. Nabuchi, 2004, Pharmaceutical Research.

Coexistence of passive and carrier-mediated processes in drug transport

Li Di, Gerhard F. Ecker, Manfred Kansy, 2010, Nature Reviews Drug Discovery.

A simulation of oral absorption using classical nucleation theory.

Kiyohiko Sugano, K. Sugano, 2009, International journal of pharmaceutics.

Prediction of oral drug absorption in humans by theoretical passive absorption model.

Kiyohiko Sugano, Minoru Machida, M. Machida, 2005, International journal of pharmaceutics.

Introduction to computational oral absorption simulation.

Kiyohiko Sugano, K. Sugano, 2009, Expert opinion on drug metabolism & toxicology.

Theoretical comparison of hydrodynamic diffusion layer models used for dissolution simulation in drug discovery and development.

Kiyohiko Sugano, K. Sugano, 2008, International journal of pharmaceutics.

Physicochemical and cell-based approach for early screening of phospholipidosis-inducing potential.

Kiyohiko Sugano, Hiroshi Yamada, Ikuo Horii, 2006, The Journal of toxicological sciences.

Prediction of passive intestinal absorption using bio-mimetic artificial membrane permeation assay and the paracellular pathway model.

Kiyohiko Sugano, Minoru Machida, K. Terada, 2002, International journal of pharmaceutics.

Oral Absorption of Poorly Water-Soluble Drugs: Computer Simulation of Fraction Absorbed in Humans from a Miniscale Dissolution Test

Kiyohiko Sugano, Yoshiki Hayashi, Minoru Machida, 2006, Pharmaceutical Research.

Theoretical dissolution model of poly-disperse drug particles in biorelevant media.

Kiyohiko Sugano, Takashi Mano, T. Mano, 2008, Journal of pharmaceutical sciences.

PAMPA--critical factors for better predictions of absorption.

Li Di, Manfred Kansy, Kiyohiko Sugano, 2007, Journal of pharmaceutical sciences.

Possible reduction of effective thickness of intestinal unstirred water layer by particle drifting effect.

Kiyohiko Sugano, K. Sugano, 2010, International journal of pharmaceutics.