Ian F. Thorpe

发表

Molecular simulations to delineate functional conformational transitions in the HCV polymerase

Ester Sesmero, Jodian A. Brown, Ian F. Thorpe, 2017, J. Comput. Chem..

Identifying Nonlinear Correlations in High Dimensional Data with Application to Protein Molecular Dynamics Simulations

Andrew M. Raim, Ian F. Thorpe, K. Adragni, 2013 .

Antibody evolution constrains conformational heterogeneity by tailoring protein dynamics

Ian F. Thorpe, S. Boxer, C. Brooks, 2006, Proceedings of the National Academy of Sciences.

178 Dual allosteric inhibitors jointly modulate structure and dynamics in the Hepatitis C Virus polymerase

Ian F. Thorpe, I. Thorpe, Jodian A. Brown, 2015, Journal of biomolecular structure & dynamics.

Using the Hepatitis C Virus RNA-Dependent RNA Polymerase as a Model to Understand Viral Polymerase Structure, Function and Dynamics

Ian F. Thorpe, I. Thorpe, E. Sesmero, 2015, Viruses.

Current advances in molecular, biochemical, and computational modeling analysis of microalgal triacylglycerol biosynthesis.

Ian F. Thorpe, I. Thorpe, Stephen M. Miller, 2016, Biotechnology advances.

Inhibitors for the hepatitis C virus RNA polymerase explored by SAR with advanced machine learning methods.

Neerja Kaushik-Basu, Marc C Nicklaus, Igor V Filippov, 2013, Bioorganic & medicinal chemistry.

Using Structural Kinetic Modeling To Identify Key Determinants of Stability in Reaction Networks.

Ian F. Thorpe, I. Thorpe, N. Carbonaro, 2017, The journal of physical chemistry. A.

Molecular evolution of affinity and flexibility in the immune system

Ian F. Thorpe, C. Brooks, I. Thorpe, 2007, Proceedings of the National Academy of Sciences.

Exploration of transferability in multiscale coarse-grained peptide models.

Gregory A Voth, Ian F. Thorpe, G. Voth, 2011, The journal of physical chemistry. B.

The coupling of structural fluctuations to hydride transfer in dihydrofolate reductase

Ian F. Thorpe, C. Brooks, I. Thorpe, 2004, Proteins.

Peptide folding using multiscale coarse-grained models.

Gregory A Voth, Ian F. Thorpe, G. Voth, 2008, The journal of physical chemistry. B.

Coarse-grained peptide modeling using a systematic multiscale approach.

Gregory A Voth, Ian F. Thorpe, G. Voth, 2007, Biophysical journal.

Conformational substates modulate hydride transfer in dihydrofolate reductase.

Ian F. Thorpe, C. Brooks, 2005, Journal of the American Chemical Society.

Allosteric inhibitors have distinct effects, but also common modes of action, in the HCV polymerase.

Ian F. Thorpe, Brittny C. Davis, Ian F Thorpe, 2015, Biophysical journal.

Thumb inhibitor binding eliminates functionally important dynamics in the hepatitis C virus RNA polymerase

Ian F. Thorpe, Brittny C. Davis, I. Thorpe, 2013, Proteins.