Steven M Cramer

发表

On-demand manufacturing of clinical-quality biopharmaceuticals

Yu Wang, Amos E. Lu, Nicholas J. Mozdzierz, 2018, Nature Biotechnology.

Improved process analytical technology for protein a chromatography using predictive principal component analysis tools

Steven M Cramer, Canping Jiang, Ying Hou, 2011, Biotechnology and bioengineering.

Investigation of protein retention and selectivity in HIC systems using quantitative structure retention relationship models

Steven M Cramer, Curt M Breneman, Asif Ladiwala, 2006, Biotechnology and bioengineering.

A priori prediction of adsorption isotherm parameters and chromatographic behavior in ion-exchange systems.

Kaushal Rege, Steven M Cramer, Asif Ladiwala, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Phenylboronate chromatography selectively separates glycoproteins through the manipulation of electrostatic, charge transfer, and cis-diol interactions.

Steven M Cramer, Ana M Azevedo, M Raquel Aires-Barros, 2014, Biotechnology journal.

Prediction of the effect of mobile-phase salt type on protein retention and selectivity in anion exchange systems.

Steven M Cramer, Minghu Song, Nihal Tugcu, 2003, Analytical chemistry.

Antibody variable region interactions with Protein A: implications for the development of generic purification processes.

Sanchayita Ghose, Steven M Cramer, Brian Hubbard, 2005, Biotechnology and bioengineering.

Evaluation and comparison of alternatives to Protein A chromatography Mimetic and hydrophobic charge induction chromatographic stationary phases.

Sanchayita Ghose, Steven M Cramer, Brian Hubbard, 2006, Journal of chromatography. A.

Model‐based process development for the purification of a modified human growth hormone using multimodal chromatography

Steven M Cramer, Lars Sejergaard, Hanne Sophie Karkov, 2014, Biotechnology progress.

Identification of chemically selective displacers using parallel batch screening experiments and quantitative structure efficacy relationship models.

Steven M Cramer, Nihal Tugcu, Curt M Breneman, 2003, Analytical chemistry.

Molecular simulations of multimodal ligand-protein binding: elucidation of binding sites and correlation with experiments.

Steven M Cramer, Shekhar Garde, S. Cramer, 2011, The journal of physical chemistry. B.

Parallel screening of selective and high-affinity displacers for proteins in ion-exchange systems.

Kaushal Rege, Steven M Cramer, Nihal Tugcu, 2004, Journal of chromatography. A.

High-throughput screening and quantitative structure-efficacy relationship models of potential displacer molecules for ion-exchange systems.

Kaushal Rege, Steven M Cramer, Curt M Breneman, 2002, Biotechnology and bioengineering.

Parallel synthesis and screening of polymers for nonviral gene delivery.

Kaushal Rege, Steven M Cramer, Ravi S Kane, 2009, Molecular pharmaceutics.

Prediction of pH-dependent chromatographic behavior in ion-exchange systems.

Steven M Cramer, C. Breneman, S. Cramer, 2007, Analytical chemistry.

Application of hydrophobic interaction displacement chromatography for an industrial protein purification.

Steven M Cramer, S. Cramer, Fang Xia, 2003, Biotechnology and bioengineering.

Affinity precipitation of a monoclonal antibody from an industrial harvest feedstock using an ELP‐Z stimuli responsive biopolymer

Steven M Cramer, Zhengjian Li, S. Cramer, 2014, Biotechnology and bioengineering.

High‐throughput screening for the development of a monoclonal antibody affinity precipitation step using ELP‐z stimuli responsive biopolymers

Steven M Cramer, S. Cramer, Wilfred Chen, 2013, Biotechnology and bioengineering.

Evaluation of selectivity in multimodal anion exchange systems: a priori prediction of protein retention and examination of mobile phase modifier effects.

Steven M Cramer, Ying Hou, S. Cramer, 2011, Journal of chromatography. A.

Chemoenzymatic synthesis and high-throughput screening of an aminoglycoside-polyamine library: identification of high-affinity displacers and DNA-binding ligands.

Kaushal Rege, Steven M Cramer, Jonathan S Dordick, 2004, Journal of the American Chemical Society.

Protein-surface interaction maps for ion-exchange chromatography.

Steven M Cramer, S. Cramer, Alexander S Freed, 2011, Langmuir : the ACS journal of surfaces and colloids.

Classification of protein adsorption and recovery at low salt conditions in hydrophobic interaction chromatographic systems.

Jie Chen, Steven M Cramer, Curt M Breneman, 2007, Journal of chromatography. A.

Methods development in multimodal chromatography with mobile phase modifiers using the steric mass action model.

Steven M Cramer, Lars Sejergaard, Hanne Sophie Karkov, 2013, Journal of chromatography. A.

An impurity characterization based approach for the rapid development of integrated downstream purification processes

Laura E Crowell, Nicholas Vecchiarello, Chaz Goodwine, 2018, Biotechnology and bioengineering.

Multidimensional high-throughput screening of displacers.

Kaushal Rege, Steven M Cramer, Asif Ladiwala, 2005, Analytical chemistry.

Improving selectivity in multimodal chromatography using controlled pH gradient elution.

Steven M Cramer, S. Cramer, Melissa A Holstein, 2012, Journal of chromatography. A.

Characterization and modeling of nonlinear hydrophobic interaction chromatographic systems.

Steven M Cramer, Deepak Nagrath, Fang Xia, 2011, Journal of chromatography. A.

The effect of geometrical presentation of multimodal cation-exchange ligands on selective recognition of hydrophobic regions on protein surfaces.

Steven M Cramer, S. Cramer, J. Woo, 2015, Journal of chromatography. A.

Use and Optimization of a Dual‐Flowrate Loading Strategy To Maximize Throughput in Protein‐A Affinity Chromatography

Sanchayita Ghose, Steven M Cramer, Deepak Nagrath, 2004, Biotechnology progress.

On-chip electrochromatography using sol-gel immobilized stationary phase with UV absorbance detection.

Steven M Cramer, S. Cramer, Rohit Jindal, 2004, Journal of chromatography. A.

Investigation of protein binding affinity and preferred orientations in ion exchange systems using a homologous protein library

Steven M Cramer, George I Makhatadze, Ying Hou, 2009, Biotechnology and bioengineering.

Utilization of lysozyme charge ladders to examine the effects of protein surface charge distribution on binding affinity in ion exchange systems.

Kaushal Rege, Steven M Cramer, Wai Keen Chung, 2010, Langmuir : the ACS journal of surfaces and colloids.

Binding capacity differences for antibodies and Fc‐fusion proteins on protein A chromatographic materials

Sanchayita Ghose, Steven M Cramer, Brian Hubbard, 2007, Biotechnology and bioengineering.

Use of MiniColumns for linear isotherm parameter estimation and prediction of benchtop column performance.

Steven M Cramer, David Robbins, Gisela Ferreira, 2015, Journal of chromatography. A.

Application of a spherical harmonics expansion approach for calculating ligand density distributions around proteins.

Steven M Cramer, Shekhar Garde, S. Cramer, 2014, The journal of physical chemistry. B.

Modeling of adsorption in hydrophobic interaction chromatography systems using a preferential interaction quadratic isotherm.

Steven M Cramer, Deepak Nagrath, Fang Xia, 2003, Journal of chromatography. A.

Mobile phase modifier effects in multimodal cation exchange chromatography

Steven M Cramer, S. Cramer, S. McCallum, 2012, Biotechnology and bioengineering.

Investigation of protein binding affinity in multimodal chromatographic systems using a homologous protein library.

Steven M Cramer, George I Makhatadze, Ying Hou, 2010, Journal of chromatography. A.

Investigation of multi-modal high-salt binding ion-exchange chromatography using quantitative structure-property relationship modeling.

Steven M Cramer, Curt M Breneman, C. Breneman, 2007, Journal of chromatography. A.

ELP-z and ELP-zz capturing scaffolds for the purification of immunoglobulins by affinity precipitation.

Steven M Cramer, Garima Chaudhary, S. Cramer, 2013, Journal of biotechnology.

Prediction of protein retention times in gradient hydrophobic interaction chromatographic systems.

Steven M Cramer, Jie Chen, S. Cramer, 2008, Journal of chromatography. A.

Defining the property space for chromatographic ligands from a homologous series of mixed-mode ligands.

Steven M Cramer, S. Cramer, J. Woo, 2015, Journal of chromatography. A.