Carol L. Williams

发表

Anju Dahiya, Carol L. Williams, Pam Porter, 2015 .

Membrane phospholipid redistribution in cancer micro-particles and implications in the recruitment of cationic protein factors

Carol L. Williams, I. Szleifer, Songwang Hou, 2014, Journal of extracellular vesicles.

The Activation of Rac1 by M3 Muscarinic Acetylcholine Receptors Involves the Translocation of Rac1 and IQGAP1 to Cell Junctions and Changes in the Composition of Protein Complexes Containing Rac1, IQGAP1, and Actin*

Carol L. Williams, C. Lanning, R. Ruiz-Velasco, 2002, The Journal of Biological Chemistry.

The Rac1 C-terminal Polybasic Region Regulates the Nuclear Localization and Protein Degradation of Rac1*

Carol L. Williams, C. Lanning, J. Daddona, 2004, Journal of Biological Chemistry.

Novel redistribution of myosin-containing filaments in cultured keratinocytes identified by a human monoclonal autoantibody

Carol L. Williams, M. Pittelkow, V. Lennon, 1989, In Vitro Cellular & Developmental Biology.

Small Cell Lung Carcinoma Exhibits Greater Phospholipase C-β1 Expression and Edelfosine Resistance Compared with Non-Small Cell Lung Carcinoma

Carol L. Williams, D. Strassheim, S. Shafer, 2000 .

Splice switching an oncogenic ratio of SmgGDS isoforms as a strategy to diminish malignancy

Carol L. Williams, M. Distefano, F. Rigo, 2020, Proceedings of the National Academy of Sciences.

β-Adrenergic receptors suppress Rap1B prenylation and promote the metastatic phenotype in breast cancer cells

Carol L. Williams, E. Lorimer, Michael D. Tyburski, 2015, Cancer biology & therapy.

An Adenosine-Mediated Signaling Pathway Suppresses Prenylation of the GTPase Rap1B and Promotes Cell Scattering

Carol L. Williams, B. Kalyanaraman, J. Auchampach, 2013, Science Signaling.

Characterization of the threshold for NAD(P)H:quinone oxidoreductase activity in intact sulforaphane-treated pulmonary arterial endothelial cells.

Carol L. Williams, G. Krenz, Adam J. Gastonguay, 2011, Free radical biology & medicine.

Expression and function of fatty acid amide hydrolase in prostate cancer

Carol L. Williams, W. Campbell, K. Nithipatikom, 2008, International journal of cancer.

Involvement of the muscarinic acetylcholine receptor in inhibition of cell migration.

Carol L. Williams, K. A. Varker, 2002, Biochemical pharmacology.

Statin-induced breast cancer cell death: role of inducible nitric oxide and arginase-dependent pathways.

Carol L. Williams, B. Kalyanaraman, S. Kotamraju, 2007, Cancer research.

Splice Variants of SmgGDS Control Small GTPase Prenylation and Membrane Localization

Carol L. Williams, A. Fields, Rongshan Li, 2010, The Journal of Biological Chemistry.

Elevated Rac1 activity changes the M3 muscarinic acetylcholine receptor-mediated inhibition of proliferation to induction of cell death.

Carol L. Williams, S. Shafer, 2004, Molecular pharmacology.

Rap1A, Rap1B, and β-Adrenergic Signaling in Autologous HCT: A Randomized Controlled Trial of Propranolol

Carol L. Williams, P. Hari, A. Szabo, 2022, The Yale journal of biology and medicine.

The complex, dynamic SpliceOme of the small GTPase transcripts altered by technique, sex, genetics, tissue specificity, and RNA base editing

Carol L. Williams, S. Chhetri, S. Rajasekaran, 2022, Frontiers in Cell and Developmental Biology.

SmgGDS: An Emerging Master Regulator of Prenylation and Trafficking by Small GTPases in the Ras and Rho Families

Carol L. Williams, A. Brandt, Olivia J. Koehn, 2021, Frontiers in Molecular Biosciences.

Striational autoantibodies: Paraneoplastic antibodies associated with thymoma and myasthenia gravis

Carol L. Williams, V. Lennon, 1991 .

Reduced expression of Wnt-1 and E-cadherin, and diminished β-catenin stability in MCF-7 breast cancer cells that overexpress protein kinase C-α

Carol L. Williams, J. Noti, 2001 .

Novel Mechanism of the Co-regulation of Nuclear Transport of SmgGDS and Rac1*

Carol L. Williams, C. Lanning, R. Ruiz-Velasco, 2003, The Journal of Biological Chemistry.

Muscarinic signaling in carcinoma cells.

Carol L. Williams, 2003, Life sciences.

Non-small and small cell lung carcinoma cell lines exhibit cell type-specific sensitivity to edelfosine-induced cell death and different cell line-specific responses to edelfosine treatment.

Carol L. Williams, S. Shafer, 2003, International journal of oncology.

SmgGDS Regulates Cell Proliferation, Migration, and NF-κB Transcriptional Activity in Non-small Cell Lung Carcinoma*

Carol L. Williams, Rongshan Li, G. Tew, 2008, Journal of Biological Chemistry.

The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences.

Carol L. Williams, 2003, Cellular signalling.

SmgGDS-558 regulates the cell cycle in pancreatic, non-small cell lung, and breast cancers

Carol L. Williams, Adam J. Gastonguay, E. Lorimer, 2014, Cell cycle.

The role of Rac1 in the regulation of NF-kB activity, cell proliferation, and cell migration in non-small cell lung carcinoma

Carol L. Williams, Adam J. Gastonguay, Tracy J. Berg, 2012, Cancer biology & therapy.

The small GTPase RhoA has greater expression in small cell lung carcinoma than in non-small cell lung carcinoma and contributes to their unique morphologies.

Carol L. Williams, K. A. Varker, S. H. Phelps, 2003, International journal of oncology.

The Chaperone Protein SmgGDS Interacts with Small GTPases Entering the Prenylation Pathway by Recognizing the Last Amino Acid in the CAAX Motif*

Carol L. Williams, M. Distefano, J. Barbieri, 2014, The Journal of Biological Chemistry.

The Nogo-B receptor promotes Ras plasma membrane localization and activation

Carol L. Williams, Wenquan Hu, Baofeng Zhao, 2016, Oncogene.

Inhibition of carcinoma cell motility by epoxyeicosatrienoic acid (EET) antagonists

Carol L. Williams, J. Falck, W. Campbell, 2010, Cancer science.

Unique in Vivo Associations with SmgGDS and RhoGDI and Different Guanine Nucleotide Exchange Activities Exhibited by RhoA, Dominant Negative RhoAAsn-19, and Activated RhoAVal-14 *

Carol L. Williams, D. Strassheim, S. H. Phelps, 2000, The Journal of Biological Chemistry.

Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer

Carol L. Williams, J. Rosenfeld, G. Getz, 2019, Nature Genetics.

Plasma membrane localization affects the RhoGAP specificity of Pseudomonas ExoS

Carol L. Williams, Yue Zhang, Qing Deng, 2007, Cellular microbiology.

Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells

Carol L. Williams, M. Dwinell, N. Zimmerman, 2015, Molecular carcinogenesis.

The SmgGDS Splice Variant SmgGDS-558 Is a Key Promoter of Tumor Growth and RhoA Signaling in Breast Cancer

Carol L. Williams, A. Mackinnon, Jian Huang, 2013, Molecular Cancer Research.

Statins Exert the Pleiotropic Effects Through Small GTP-Binding Protein Dissociation Stimulator Upregulation With a Resultant Rac1 Degradation

Carol L. Williams, H. Shimokawa, Y. Fukumoto, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B.

Carol L. Williams, J. Prokop, E. Lorimer, 2016, Journal of molecular biology.

The Tumor-suppressive Small GTPase DiRas1 Binds the Noncanonical Guanine Nucleotide Exchange Factor SmgGDS and Antagonizes SmgGDS Interactions with Oncogenic Small GTPases*

Carol L. Williams, C. Fierke, Kathleen R. Noon, 2016, The Journal of Biological Chemistry.

A new signaling paradigm to control the prenylation and trafficking of small GTPases

Carol L. Williams, 2013, Cell cycle.

Cannabinoid receptor type 1 (CB1) activation inhibits small GTPase RhoA activity and regulates motility of prostate carcinoma cells.

Carol L. Williams, W. Campbell, K. Nithipatikom, 2012, Endocrinology.

P2Y2 Purinergic and M3 Muscarinic Acetylcholine Receptors Activate Different Phospholipase C-β Isoforms That Are Uniquely Susceptible to Protein Kinase C-dependent Phosphorylation and Inactivation*

Carol L. Williams, D. Strassheim, 2000, The Journal of Biological Chemistry.

GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS

Carol L. Williams, M. Distefano, K. Suazo, 2023, The Journal of biological chemistry.

Structural and biophysical properties of farnesylated KRas interacting with the chaperone SmgGDS-558.

Carol L. Williams, A. Grishaev, M. Lösche, 2022, Biophysical journal.

Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells

Carol L. Williams, J. Joseph, B. Kalyanaraman, 2011, Cancer biology & therapy.

M3 Muscarinic Acetylcholine Receptors Regulate Cytoplasmic Myosin by a Process Involving RhoA and Requiring Conventional Protein Kinase C Isoforms*

Carol L. Williams, D. Strassheim, R. Aronstam, 1999, The Journal of Biological Chemistry.

Nicotinic Acetylcholine Receptors of Muscle and Neuronal (α7) Types Coexpressed in a Small Cell Lung Carcinoma

Carol L. Williams, V. Lennon, G. Griesmann, 1997 .

Serum Antibodies and Monoclonal Antibodies Secreted by Thymic B‐Cell Clones from Patients with Myasthenia Gravis Define Striational Antigens a

Carol L. Williams, M. Momoi, V. Lennon, 1987, Annals of the New York Academy of Sciences.

Human monoclonal striational autoantibodies isolated from thymic B lymphocytes of patients with myasthenia gravis use VH and VL gene segments associated with the autoimmune repertoire

Carol L. Williams, V. Pascual, V. Lennon, 1992, European journal of immunology.

Paraneoplastic cerebellar autoantibodies associated with gynecological cancer bind to myenteric plexus neurons

Carol L. Williams, V. Lennon, H. Altermatt, 1991, Annals of neurology.

Identification and characterization of the unique guanine nucleotide exchange factor, SmgGDS, in vascular smooth muscle cells

Carol L. Williams, W. Campbell, Rebecca Thill, 2008, Journal of Cellular Biochemistry.

Regulation of E-cadherin-mediated adhesion by muscarinic acetylcholine receptors in small cell lung carcinoma

Carol L. Williams, A. Hummel, A. Hummel, 1993, The Journal of cell biology.

Regulation of integrin-mediated adhesion by muscarinic acetylcholine receptors and protein kinase C in small cell lung carcinoma.

Carol L. Williams, C. L. Williams, S. Shafer, 1998, Chest.

The Rac 1 C-terminal Polybasic Region Regulates the Nuclear Localization and Protein Degradation of Rac 1 *

Carol L. Williams, C. Lanning, J. Daddona, 2004 .

Transepithelial transport of drugs by the multidrug transporter in cultured Madin-Darby canine kidney cell epithelia.

Carol L. Williams, I. Pastan, M. Gottesman, 1989, The Journal of biological chemistry.

Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer

Carol L. Williams, J. Rosenfeld, G. Getz, 2019, Nature Genetics.

The Chaperone Protein SmgGDS Interacts with Small GTPases Entering the Prenylation Pathway by Recognizing the Last Amino Acid in the CAAX Motif*

Carol L. Williams, M. Distefano, J. Barbieri, 2014, Journal of Biological Chemistry.

Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B.

Carol L. Williams, J. Prokop, E. Lorimer, 2016, Journal of molecular biology.

Striational autoantibodies: quantitative detection by enzyme immunoassay in myasthenia gravis, thymoma, and recipients of D-penicillamine or allogeneic bone marrow.

Carol L. Williams, M. Momoi, V. Lennon, 1988, Mayo Clinic proceedings.