Steven P Gygi

发表

BioPlex Display: An Interactive Suite for Large-Scale AP-MS Protein-Protein Interaction Data.

Devin K Schweppe, Edward L Huttlin, J Wade Harper, 2018, Journal of proteome research.

A probability-based approach for high-throughput protein phosphorylation analysis and site localization

Steven P Gygi, Scott A Gerber, Sean A Beausoleil, 2006, Nature Biotechnology.

Comparative evaluation of mass spectrometry platforms used in large-scale proteomics investigations

Steven P Gygi, Brendan K Faherty, Joshua E Elias, 2005, Nature Methods.

Improved Monoisotopic Mass Estimation for Deeper Proteome Coverage.

Ramin Rad, Julian Mintseris, Devin K Schweppe, 2020, Journal of proteome research.

Compositional Proteomics: Effects of Spatial Constraints on Protein Quantification Utilizing Isobaric Tags

Michael P Weekes, Edward L Huttlin, Steven P Gygi, 2017, Journal of proteome research.

Streamlined Tandem Mass Tag (SL-TMT) Protocol: An Efficient Strategy for Quantitative (Phospho)proteome Profiling Using Tandem Mass Tag-Synchronous Precursor Selection-MS3.

Steven P Gygi, Joao A Paulo, José Navarrete-Perea, 2018, Journal of proteome research.

TomahaqCompanion: A Tool for the Creation and Analysis of Isobaric Label Based Multiplexed Targeted Assays.

Jae Choi, Devin K Schweppe, Steven P Gygi, 2018, Journal of proteome research.

TKO6: A Peptide Standard To Assess Interference for Unit-Resolved Isobaric Labeling Platforms.

Steven P Gygi, Joao A Paulo, Jose Navarrete-Perea, 2018, Journal of proteome research.

The effects of nonignorable missing data on label-free mass spectrometry proteomics experiments.

Joseph G Ibrahim, Steven P Gygi, Xian Chen, 2018, The annals of applied statistics.

Sample multiplexing for targeted pathway proteomics in aging mice

Devin K Schweppe, Steven P Gygi, Devin K. Schweppe, 2020, Proceedings of the National Academy of Sciences.

Isobaric Tag‐Based Protein Profiling across Eight Human Cell Lines Using High‐Field Asymmetric Ion Mobility Spectrometry and Real‐Time Database Searching

Steven P Gygi, Joao A Paulo, Xinyue Liu, 2020, Proteomics.

Active Instrument Engagement Combined with a Real-Time Database Search for Improved Performance of Sample Multiplexing Workflows.

Julian Mintseris, Devin K Schweppe, Steven P Gygi, 2019, Journal of proteome research.

Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry

Steven P Gygi, Joshua E Elias, Joshua E. Elias, 2007, Nature Methods.

Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics.

Ramin Rad, Devin K Schweppe, Qing Yu, 2020, Journal of proteome research.

Web-Based Search Tool for Visualizing Instrument Performance Using the Triple Knockout (TKO) Proteome Standard.

Ramin Rad, Steven P Gygi, Joao A Paulo, 2018, Journal of proteome research.

The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry

Steven P Gygi, Judit Villén, S. Gygi, 2008, Nature Protocols.

Correct Interpretation of Comprehensive Phosphorylation Dynamics Requires Normalization by Protein Expression Changes*

Edward L Huttlin, Steven P Gygi, Wilhelm Haas, 2011, Molecular & Cellular Proteomics.

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.

Steven P Gygi, Wilhelm Haas, P. Puigserver, 2005, Nature.

Phosphoproteomic Analysis of the Developing Mouse Brain*S

Steven P Gygi, Sean A Beausoleil, Judit Villén, 2004, Molecular & Cellular Proteomics.

Global analysis of protein expression and phosphorylation of three stages of Plasmodium falciparum intraerythrocytic development.

Edward L Huttlin, Steven P Gygi, Edward L. Huttlin, 2013, Journal of proteome research.

Quantitative mass spectrometry-based multiplexing compares the abundance of 5000 S. cerevisiae proteins across 10 carbon sources.

Steven P Gygi, Jeremy D O'Connell, Joao A Paulo, 2016, Journal of proteomics.

Semiquantitative Proteomic Analysis of Rat Forebrain Postsynaptic Density Fractions by Mass Spectrometry*

Steven P Gygi, Junmin Peng, Dongmei Cheng, 2004, Journal of Biological Chemistry.

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase.

Steven P Gygi, S. Gygi, J. Blenis, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Proteomics of phosphorylation and protein dynamics during fertilization and meiotic exit in the Xenopus egg

Leonid Peshkin, Steven P Gygi, Allon M Klein, 2017, Proceedings of the National Academy of Sciences.

Angiogenin-induced tRNA fragments inhibit translation initiation.

Steven P Gygi, Pavel Ivanov, S. Gygi, 2011, Molecular cell.

In situ observation of protein phosphorylation by high-resolution NMR spectroscopy

Steven P Gygi, Wilhelm Haas, Gerhard Wagner, 2008, Nature Structural &Molecular Biology.

A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway.

Steven P Gygi, Wilhelm Haas, S. Gygi, 2007, Molecular cell.

Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5′TOP mRNA translation

Edward L Huttlin, Steven P Gygi, Edward L. Huttlin, 2014, Genes & development.

The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.

Steven P Gygi, David M Sabatini, S. Gygi, 2014, Cell reports.

Improved Method for Determining Absolute Phosphorylation Stoichiometry Using Bayesian Statistics and Isobaric Labeling.

Steven P Gygi, Joao A Paulo, S. Gygi, 2017, Journal of proteome research.

Characterization of Plasmodium falciparum Atypical Kinase PfPK7- Dependent Phosphoproteome.

Edward L Huttlin, Steven P Gygi, Ratna Chakrabarti, 2018, Journal of proteome research.

Transcription factor networks in Drosophila melanogaster.

Julian Mintseris, Dong-Yeon Cho, Steven P Gygi, 2014, Cell reports.

Phosphoproteome analysis of Drosophila melanogaster embryos.

Julian Mintseris, Steven P Gygi, Sean A Beausoleil, 2008, Journal of proteome research.

Characterization of Mouse Spleen Cells by Subtractive Proteomics*S

Steven P Gygi, Scott A Gerber, Sean A Beausoleil, 2005, Molecular & Cellular Proteomics.

Proteome-wide systems analysis of a cellulosic biofuel-producing microbe

Steven P Gygi, Wilhelm Haas, John Aach, 2011, Molecular Systems Biology.

Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells

Steven P Gygi, Gerhard Wagner, R. E. Luna, 2014, Proceedings of the National Academy of Sciences.

Global Analysis of Protein Expression and Phosphorylation Levels in Nicotine-Treated Pancreatic Stellate Cells.

Steven P Gygi, Joao A Paulo, S. Gygi, 2015, Journal of proteome research.

Certain Pairs of Ubiquitin-conjugating Enzymes (E2s) and Ubiquitin-Protein Ligases (E3s) Synthesize Nondegradable Forked Ubiquitin Chains Containing All Possible Isopeptide Linkages*

Steven P Gygi, S. Gygi, A. Goldberg, 2007, Journal of Biological Chemistry.

Multiplexed in vivo His-tagging of enzyme pathways for in vitro single-pot multienzyme catalysis.

Steven P Gygi, Adam H. Marblestone, Wilhelm Haas, 2012, ACS synthetic biology.

Akt–RSK–S6 Kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases

Steven P Gygi, Ailan Guo, Judit Villén, 2010, Science Signaling.

Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors.

Steven P Gygi, Scott A Gerber, S. Gygi, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Large-scale characterization of HeLa cell nuclear phosphoproteins.

Steven P Gygi, Sean A Beausoleil, Judit Villén, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Hyperplexing: A Method for Higher-Order Multiplexed Quantitative Proteomics Provides a Map of the Dynamic Response to Rapamycin in Yeast

Steven P Gygi, Noah Dephoure, S. Gygi, 2012, Science Signaling.

ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex.

Steven P Gygi, Jan Seebacher, S. Gygi, 2010, Genes & development.

Proteome analysis of low-abundance proteins using multidimensional chromatography and isotope-coded affinity tags.

Ruedi Aebersold, Timothy J Griffin, Steven P Gygi, 2002, Journal of proteome research.

Generation of multiple reporter ions from a single isobaric reagent increases multiplexing capacity for quantitative proteomics.

Ramin Rad, Steven P Gygi, Wilhelm Haas, 2015, Analytical chemistry.

The effects of mass accuracy, data acquisition speed, and search algorithm choice on peptide identification rates in phosphoproteomics

Steven P Gygi, Wilhelm Haas, Corey E Bakalarski, 2007, Analytical and bioanalytical chemistry.

SILVER helps assign peptides to tandem mass spectra using intensity-based scoring

Steven P Gygi, Frederick P Roth, Joshua E Elias, 2004, Journal of the American Society for Mass Spectrometry.

A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery

Steven P Gygi, Pamela A Silver, P. Silver, 2003, Proceedings of the National Academy of Sciences of the United States of America.

The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications.

Steven P Gygi, Scott A Gerber, Donald S Kirkpatrick, 2005, Methods.

Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins.

Etienne Gagnon, Steven P Gygi, Mark A Behlke, 2012, RNA.

Proteomic insights into ubiquitin and ubiquitin-like proteins.

Steven P Gygi, Donald S Kirkpatrick, S. Gygi, 2005, Current opinion in chemical biology.

Intensity-based protein identification by machine learning from a library of tandem mass spectra

Steven P Gygi, Frederick P Roth, Joshua E Elias, 2004, Nature Biotechnology.

Signaling networks assembled by oncogenic EGFR and c-Met

Steven P Gygi, Ailan Guo, Judit Villén, 2008, Proceedings of the National Academy of Sciences.

Reconstitution of the Mycobacterium tuberculosis pupylation pathway in Escherichia coli

Steven P Gygi, Fiona McAllister, S. Gygi, 2011, EMBO reports.

The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8.

Jürg Bähler, Steven P Gygi, Judit Villén, 2008, Genes & development.

The impact of peptide abundance and dynamic range on stable-isotope-based quantitative proteomic analyses.

Steven P Gygi, Scott A Gerber, Judit Villén, 2008, Journal of proteome research.

Protein Profiling with Cleavable Isotope-coded Affinity Tag (cICAT) Reagents

Hanno Steen, Steven P Gygi, Jiaxu Li, 2003, Molecular & Cellular Proteomics.

Abraxas and RAP80 Form a BRCA1 Protein Complex Required for the DNA Damage Response

Steven P Gygi, B. A. Ballif, S. Elledge, 2007, Science.

A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability.

J Wade Harper, Steven P Gygi, Britt Adamson, 2010, Molecular cell.

Ubiquitin-Dependent Modification of Skeletal Muscle by the Parasitic Nematode, Trichinella spiralis

Michael P Weekes, Steven P Gygi, David B Ascher, 2016, PLoS pathogens.

Enhanced analysis of metastatic prostate cancer using stable isotopes and high mass accuracy instrumentation.

Steven P Gygi, Brendan K Faherty, Scott A Gerber, 2006, Journal of proteome research.

The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis.

Steven P Gygi, Joshua E Elias, Joshua E. Elias, 2005, Human molecular genetics.

A proteomics approach to understanding protein ubiquitination

Steven P Gygi, Joshua E Elias, Junmin Peng, 2003, Nature Biotechnology.