Michael T Hemann

A mammalian functional-genetic approach to characterizing cancer therapeutics.

Douglas A Lauffenburger, Hai Jiang, Justin R Pritchard, 2010, Nature chemical biology.

Addressing genetic tumor heterogeneity through computationally predictive combination therapy.

Douglas A Lauffenburger, Boyang Zhao, Justin R Pritchard, 2013, Cancer discovery.

Predicting cancer drug mechanisms of action using molecular network signatures.

Douglas A Lauffenburger, Justin R Pritchard, Michael T Hemann, 2013, Molecular bioSystems.

Tumor promotion by Mdm2 splice variants unable to bind p53.

Elisa de Stanchina, Carlos Cordon-Cardo, Michael T Hemann, 2003, Cancer research.

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

Yves Pommier, Junko Murai, Justin R Pritchard, 2017, Nature Medicine.

Intratumor heterogeneity alters most effective drugs in designed combinations

Douglas A Lauffenburger, Boyang Zhao, Michael T Hemann, 2014, Proceedings of the National Academy of Sciences.