Catherine L. Worth

发表

SuperSweet—a resource on natural and artificial sweetening agents

Jessica Ahmed, Saskia Preissner, Mathias Dunkel, 2010, Nucleic Acids Res..

GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models

Catherine L. Worth, Gerd Krause, Annika Kreuchwig, 2011, BMC Bioinformatics.

FragmentStore—a comprehensive database of fragments linking metabolites, toxic molecules and drugs

Corinna Blasse, Jessica Ahmed, Mathias Dunkel, 2010, Nucleic Acids Res..

A Structural Bioinformatics Approach to the Analysis of nonsynonymous Single nucleotide polymorphisms (nsSNPS) and their Relation to Disease

Sungsam Gong, David F. Burke, Tom L. Blundell, 2007, J. Bioinform. Comput. Biol..

BMC Bioinformatics BioMed Central Methodology article Genome bioinformatic analysis of nonsynonymous SNPs

David F. Burke, Tom L. Blundell, Catherine L. Worth, 2006 .

GPCR-SSFE 2.0—a fragment-based molecular modeling web tool for Class A G-protein coupled receptors

Catherine L. Worth, Gerd Krause, Johanna K. S. Tiemann, 2017, Nucleic Acids Res..

AIRE's CARD Revealed, a New Structure for Central Tolerance Provokes Transcriptional Plasticity*

Catherine L. Worth, Hamish S. Scott, Anne Cooke, 2008, Journal of Biological Chemistry.

Comparative Sequence and Structural Analyses of G-Protein-Coupled Receptor Crystal Structures and Implications for Molecular Models

Catherine L. Worth, Gerd Krause, Gunnar Kleinau, 2009, PloS one.

Binding sites in membrane proteins--diversity, druggability and prospects.

Mathias Dunkel, Catherine L. Worth, Robert Preissner, 2012, European journal of cell biology.

Cells and gene expression programs in the adult human heart

Matthias Heinig, Daniel Reichart, Sarah A. Teichmann, 2020, bioRxiv.

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

Thomas Zichner, Adrian M. Stütz, Jan O. Korbel, 2015, Nature Genetics.

Structural–Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at Work

Catherine L. Worth, H. Biebermann, P. Scheerer, 2017, Front. Endocrinol..

Structural and functional constraints in the evolution of protein families

Catherine L. Worth, T. Blundell, Sungsam Gong, 2009, Nature Reviews Molecular Cell Biology.

The Translational Landscape of the Human Heart

Catherine L. Worth, S. V. Heesch, J. Seidman, 2019, Cell.

On the evolutionary conservation of hydrogen bonds made by buried polar amino acids: the hidden joists, braces and trusses of protein architecture

Catherine L. Worth, T. Blundell, C. Worth, 2010, BMC Evolutionary Biology.

Meet Me Halfway: When Genomics Meets Structural Bioinformatics

Catherine L. Worth, Tammy M. K. Cheng, T. Blundell, 2011, Journal of cardiovascular translational research.

SDM—a server for predicting effects of mutations on protein stability and malfunction

Catherine L. Worth, T. Blundell, R. Preissner, 2011, Nucleic Acids Res..

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

Roland Eils, Thomas Zichner, Hans Lehrach, 2013, Nature Genetics.

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies

Catherine L. Worth, S. Teichmann, J. Seidman, 2022, Science.

Evolutionary analyses reveal immune cell receptor GPR84 as a conserved receptor for bacteria-derived molecules

Catherine L. Worth, P. Scheerer, C. Worth, 2022, iScience.

Structural changes of TasA in biofilm formation of Bacillus subtilis

Catherine L. Worth, P. Schmieder, U. Heinemann, 2018, Proceedings of the National Academy of Sciences.

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4

Catherine L. Worth, M. Jarvelin, C. Gieger, 2021, Nature Communications.

Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery

Catherine L. Worth, B. L. Sibanda, T. Blundell, 2006, Philosophical Transactions of the Royal Society B: Biological Sciences.

Cells of the adult human heart

Catherine L. Worth, Hao Zhang, S. Teichmann, 2020, Nature.

Residues of a proposed gate region in type I ATP-binding cassette import systems are crucial for function as revealed by mutational analysis.

Catherine L. Worth, R. Preissner, E. Schneider, 2013, Biochimica et biophysica acta.

Polybacterial intracellular coinfection of epithelial stem cells in periodontitis

Catherine L. Worth, S. Wallet, K. Tyc, 2023, bioRxiv.

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors

Catherine L. Worth, T. Borodina, H. Lehrach, 2017, Nature Communications.

From Molecular Details of the Interplay between Transmembrane Helices of the Thyrotropin Receptor to General Aspects of Signal Transduction in Family A G-protein-coupled Receptors (GPCRs)*

Catherine L. Worth, Gerd Krause, Annika Kreuchwig, 2011, The Journal of Biological Chemistry.

Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level

Catherine L. Worth, B. Wiesner, H. Biebermann, 2017, Cellular and Molecular Life Sciences.

Research resource: Update and extension of a glycoprotein hormone receptors web application.

Catherine L. Worth, G. Krause, C. Worth, 2011, Molecular endocrinology.

Structural bioinformatics mutation analysis reveals genotype–phenotype correlations in von Hippel‐Lindau disease and suggests molecular mechanisms of tumorigenesis

Catherine L. Worth, Tom L Blundell, T. Blundell, 2009, Proteins.

Estimating the Effects Of Single Nucleotide Polymorphisms On Protein Structure: How Good are we at Identifying Likely Disease Associated Mutations?

Catherine L. Worth, T. Blundell, David Burke, 2022 .