Carol A. Mulrooney

发表

An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries

Paul A. Clemons, Willmen Youngsaye, Dennis Moccia, 2013, Journal of Computer-Aided Molecular Design.

An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.

Nathan T. Ross, Carol A. Mulrooney, Jeremy R. Duvall, 2010, Journal of the American Chemical Society.

Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.

Giovanni Muncipinto, Lakshmi B. Akella, Byung-Chul Suh, 2012, The Journal of organic chemistry.

Diversity-Oriented Synthesis-Facilitated Medicinal Chemistry: Toward the Development of Novel Antimalarial Agents

Carol A. Mulrooney, Jeremy R. Duvall, S. Schreiber, 2014, Journal of medicinal chemistry.

ML238: An Antimalarial Small Molecule of a Unique Structural Class

Carol A. Mulrooney, S. Schreiber, X. Su, 2011 .

Synthesis of 2-Aryl-1-hydroxyazaindoles and 2-Arylazaindoles via Oxidation of o-Hydroxyaminostyrylpyridines

Carol A. Mulrooney, D. Kuzmich, 2003 .

Mild aromatic palladium-catalyzed protodecarboxylation: kinetic assessment of the decarboxylative palladation and the protodepalladation steps.

Carol A. Mulrooney, M. Kozlowski, O. Gutierrez, 2013, The Journal of organic chemistry.

Enantioselective oxidative biaryl coupling reactions catalyzed by 1,5-diazadecalin metal complexes: efficient formation of chiral functionalized BINOL derivatives.

Carol A. Mulrooney, Jaemoon Yang, M. Kozlowski, 2003, The Journal of organic chemistry.

Progress towards the Synthesis of Purpuromycin and Nigerone

Carol A. Mulrooney, M. Kozlowski, S. P. Waters, 2003 .

Practical asymmetric synthesis of β-hydroxy γ-amino acids via complimentary aldol reactions.

Carol A. Mulrooney, Jeremy R. Duvall, D. Young, 2011, Tetrahedron.

Asymmetric total synthesis of nigerone.

Carol A. Mulrooney, M. Kozlowski, E. Divirgilio, 2007, Organic letters.

General approach for the synthesis of chiral perylenequinones via catalytic enantioselective oxidative biaryl coupling.

Carol A. Mulrooney, M. Kozlowski, Xiaolin Li, 2003, Journal of the American Chemical Society.

Perylenequinone natural products: enantioselective synthesis of the oxidized pentacyclic core.

Carol A. Mulrooney, M. Kozlowski, Barbara J. Morgan, 2010, The Journal of organic chemistry.

DNA-encoded chemical libraries

Samu Melkko, Dario Neri, Christoph E Dumelin, 2022, Nature Reviews Methods Primers.

Build/couple/pair strategy for the synthesis of stereochemically diverse macrolactams via head-to-tail cyclization.

Carol A. Mulrooney, Jeremy R. Duvall, Anita Vrcic, 2012, ACS combinatorial science.

High Throughput Screen Identifies Interferon γ-Dependent Inhibitors of Toxoplasma gondii Growth.

Joshua A. Bittker, Carol A. Mulrooney, S. Schreiber, 2018, ACS Infectious Diseases.

High throughput screen identifies IFN-γ-dependent inhibitors of Toxoplasma gondii growth

Joshua A. Bittker, Carol A. Mulrooney, S. Schreiber, 2018, bioRxiv.

Diversity-Oriented Synthesis Probe Targets Plasmodium falciparum Cytochrome b Ubiquinone Reduction Site and Synergizes With Oxidation Site Inhibitors

Carol A. Mulrooney, Jeremy R. Duvall, S. Schreiber, 2014, The Journal of infectious diseases.

Novel diversity-oriented synthesis-derived respiratory syncytial virus inhibitors identified via a high throughput replicon-based screen.

Carol A. Mulrooney, Jeremy R. Duvall, M. Foley, 2016, Antiviral research.

Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria

Menghang Xia, Christopher P. Austin, Michel Weïwer, 2011, ACS medicinal chemistry letters.

Development of a catalytic aromatic decarboxylation reaction.

Carol A. Mulrooney, E. O'brien, M. Kozlowski, 2007, Organic letters.

Perylenequinone natural products: evolution of the total synthesis of cercosporin.

Carol A. Mulrooney, M. Kozlowski, Barbara J. Morgan, 2010, The Journal of organic chemistry.

Perylenequinone natural products: total syntheses of the diastereomers (+)-phleichrome and (+)-calphostin D by assembly of centrochiral and axial chiral fragments.

Carol A. Mulrooney, E. O'brien, M. Kozlowski, 2010, The Journal of organic chemistry.

Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.

Carol A. Mulrooney, Jeremy R. Duvall, M. Foley, 2012, The Journal of organic chemistry.

Perylenequinone natural products: total synthesis of hypocrellin A.

Carol A. Mulrooney, E. O'brien, M. Kozlowski, 2010, The Journal of organic chemistry.