Andrew L Kung

发表

Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover’s Distance

Yongxin Chen, Joseph O Deasy, Romeil Sandhu, 2017, bioRxiv.

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.

Lars Bullinger, Andrew L Kung, Scott A Armstrong, 2011, Cancer cell.

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Donna Neuberg, Steven M Kornblau, Johannes Köster, 2016, Cancer cell.

Antileukemic effects of the novel, mutant FLT3 inhibitor NVP-AST487: effects on PKC412-sensitive and -resistant FLT3-expressing cells.

Pascal Furet, Guido Bold, Arghya Ray, 2008, Blood.

Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination.

Andrew L Kung, R. DePinho, W. Kaelin, 2003, Molecular imaging.

Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins.

Leigh Zawel, Santosh Kesari, David S Ziegler, 2008, The Journal of clinical investigation.

A stapled p53 helix overcomes HDMX-mediated suppression of p53.

Tina N. Davis, Andrew L Kung, G. Wahl, 2010, Cancer cell.

A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.

Evripidis Gavathiotis, Andrew L Kung, James L LaBelle, 2012, The Journal of clinical investigation.

A novel noninvasive model of endometriosis for monitoring the efficacy of antiangiogenic therapy.

Tae Funakoshi, Ronit Satchi-Fainaro, Andrew L Kung, 2006, The American journal of pathology.

A HIF1α Regulatory Loop Links Hypoxia and Mitochondrial Signals in Pheochromocytomas

Sandro Santagata, Marta Barontini, Gabriela Sanso, 2005, PLoS genetics.

Patient-Driven Discovery, Therapeutic Targeting, and Post-Clinical Validation of a Novel AKT1 Fusion-Driven Cancer.

Andrea Califano, Stephen S Roberts, Ryma Benayed, 2019, Cancer discovery.

Optical techniques for tracking multiple myeloma engraftment, growth, and response to therapy.

Charles P. Lin, Costas Pitsillides, Charles P Lin, 2011, Journal of biomedical optics.

Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation

Todd R Golub, Kimberly Stegmaier, Andrew L Kung, 2008, Proceedings of the National Academy of Sciences.

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.

Donna Neuberg, Doriano Fabbro, Arghya Ray, 2005, Cancer cell.

Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification.

Rob Pieters, Todd R Golub, John H Kersey, 2003, Cancer cell.

New cast for a new era: preclinical cancer drug development revisited.

Kwok-Kin Wong, Andrew L Kung, Kwok-Kin Wong, 2013, The Journal of clinical investigation.

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Donna Neuberg, Steven M Kornblau, Johannes Köster, 2016, Cancer cell.

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors

Andrew L Kung, R. Klein, R. Segal, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Potentiation of antileukemic therapies by Smac mimetic, LBW242: effects on mutant FLT3-expressing cells

Arghya Ray, Jan Cools, Leigh Zawel, 2007, Molecular Cancer Therapeutics.

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

Yonghong Xiao, Jen-Chieh Tseng, Robert A Copeland, 2011, Cancer cell.

Structural basis for negative regulation of hypoxia-inducible factor-1α by CITED2

Gerhard Wagner, Andrew L Kung, G. Wagner, 2003, Nature Structural Biology.

Sound credit scores and financial decisions despite cognitive aging

Rameen Beroukhim, William C Hahn, Pratiti Bandopadhayay, 2014, Proceedings of the National Academy of Sciences.

Signature-Based Small Molecule Screening Identifies Cytosine Arabinoside as an EWS/FLI Modulator in Ewing Sarcoma

Todd R Golub, Kimberly Stegmaier, Andrew L Kung, 2007, PLoS medicine.

Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma.

Charles P. Lin, Daniel Côté, Charles P Lin, 2007, Blood.

In vivo assessment of RAS-dependent maintenance of tumor angiogenesis by real-time magnetic resonance imaging.

Ralph Weissleder, Lynda Chin, Andrew L Kung, 2005, Cancer research.

HOXA9 is required for survival in human MLL-rearranged acute leukemias.

Tina N. Davis, Andrew L Kung, Scott A Armstrong, 2009, Blood.

A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors

Paul A Clemons, Andrea Califano, Mariano J. Alvarez, 2018, Nature Genetics.

Monoallele deletion of CBP leads to pericentromeric heterochromatin condensation through ESET expression and histone H3 (K9) methylation.

Andrew L Kung, R. Ferrante, A. Kung, 2008, Human molecular genetics.

Proteomic and genetic approaches identify Syk as an AML target.

Tina N. Davis, Steven A Carr, William C Hahn, 2009, Cancer cell.

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing.

Shridar Ganesan, Klaus Rajewsky, Andrew L Kung, 2005, Genes & development.

Therapeutic targeting of apoptosis pathways in cancer

David S Ziegler, Andrew L Kung, A. Kung, 2008, Current opinion in oncology.

The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.

Gabriela Alexe, Giovanni Roti, Nicola Tolliday, 2012, The Journal of clinical investigation.

Integrative analysis reveals an outcome-associated and targetable pattern of p53 and cell cycle deregulation in diffuse large B cell lymphoma.

Stefano Monti, Ahmet Dogan, Donna Neuberg, 2012, Cancer cell.

Mice heterozygous for CREB binding protein are hypersensitive to γ-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm.

Uthra Suresh, Andrew L Kung, Yidong Chen, 2012, Experimental Hematology.

Noninvasive Bioluminescence Imaging of Luciferase Expressing Intracranial U87 Xenografts: Correlation with Magnetic Resonance Imaging Determined Tumor Volume and Longitudinal Use in Assessing Tumor Growth and Antiangiogenic Treatment Effect

Ning Lin, Shigeru Kiryu, Bob S Carter, 2006, Neurosurgery.

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation.

Giovanni Roti, Lynn VerPlank, Nicola Tolliday, 2013, Chemistry & biology.

A class of human proteins that deliver functional proteins into mammalian cells in vitro and in vivo.

Tina N. Davis, David R. Liu, Jen-Chieh Tseng, 2011, Chemistry & biology.

H3K79 methylation profiles define murine and human MLL-AF4 leukemias.

Xiaobo Xia, Andrew L Kung, Scott A Armstrong, 2008, Cancer cell.