David J Chen

发表

Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells

Sylvain V Costes, Teresa Neumaier, Mina J Bissell, 2011, Proceedings of the National Academy of Sciences.

The Major DNA Repair Pathway after Both Proton and Carbon-Ion Radiation is NHEJ, but the HR Pathway is More Relevant in Carbon Ions

Takeji Sakae, Koji Tsuboi, Takaaki Ishikawa, 2015, Radiation research.

Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair.

Ulf Hellman, David J. Chen, Rolf Lewensohn, 2011, Genes & development.

Role of non-homologous end joining (NHEJ) in maintaining genomic integrity.

David J. Chen, David J Chen, B. Chen, 2006, DNA repair.

DNA double strand break repair via non-homologous end-joining.

David J. Chen, David J Chen, Anthony J Davis, 2013, Translational cancer research.

Tumor cell radiosensitivity is a major determinant of tumor response to radiation.

David J. Chen, Akihiro Kurimasa, David J Chen, 2006, Cancer research.

Cryo-EM structure of the DNA-dependent protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding.

Phoebe L Stewart, David J. Chen, David J Chen, 2008, Structure.

Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma.

Mitsuo Sato, David J. Chen, John D Minna, 2007, Cancer research.

Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation.

David J. Chen, Aroumougame Asaithamby, David J Chen, 2011, Mutation research.

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a).

John M Sedivy, David J. Chen, David J Chen, 2004, Molecular cell.

Phosphoproteome profiling of human skin fibroblast cells in response to low- and high-dose irradiation.

Matthew E Monroe, Feng Yang, Ruihua Fang, 2006, Journal of proteome research.

A human breast cell model of preinvasive to invasive transition.

Roy A Jensen, Joe W Gray, Koei Chin, 2008, Cancer research.

Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.

Bernhard Kuster, Matthias Mann, Moshe Oren, 2011, Molecular cell.

Gene Expression Changes in Normal Human Skin Fibroblasts Induced by HZE-Particle Radiation

Aloke Chatterjee, David J. Chen, David J Chen, 2005, Radiation research.

Unrepaired clustered DNA lesions induce chromosome breakage in human cells

David J. Chen, Aroumougame Asaithamby, David J Chen, 2011, Proceedings of the National Academy of Sciences.

Gene Expression Profiles of Normal Human Fibroblasts after Exposure to Ionizing Radiation: A Comparative Study of Low and High Doses

Jan-Fang Cheng, Jeng-Jong Hwang, David J. Chen, 2005, Radiation research.

Room-temperature single-nucleotide polymorphism and multiallele DNA detection using fluorescent nanocrystals and microarrays.

A Paul Alivisatos, Wolfgang J Parak, Daniele Gerion, 2003, Analytical chemistry.

Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities.

Steven M Yannone, Joe W Gray, David J. Chen, 2010, Oncology reports.