Ann M Leen

Optimizing the production of suspension cells using the G-Rex “M” series

David Hsu, John M Centanni, Pradip Bajgain, 2014, Molecular therapy. Methods & clinical development.

Good manufacturing practice-grade cytotoxic T lymphocytes specific for latent membrane proteins (LMP)-1 and LMP2 for patients with Epstein-Barr virus-associated lymphoma.

Stephen Gottschalk, Adrian P Gee, Ann M Leen, 2011, Cytotherapy.

Challenges of T cell therapies for virus-associated diseases after hematopoietic stem cell transplantation

Ann M Leen, Cliona M Rooney, C. Rooney, 2010, Expert opinion on biological therapy.

Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals

Chung-Che Chang, Adrian P Gee, Helen E Heslop, 2006, Nature Medicine.

Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer.

Chung-Che Chang, Stephen Gottschalk, Adrian P Gee, 2007, Blood.

Accelerated Production of Antigen-specific T Cells for Preclinical and Clinical Applications Using Gas-permeable Rapid Expansion Cultureware (G-Rex)

Helen E Heslop, Ann M Leen, Cliona M Rooney, 2010, Journal of immunotherapy.