J. E. Hyde

发表

The non-histone proteins of the rat liver nucleus and their distribution amongst chromatin fractions as produced by nuclease digestion

H. G. Zachau, J. E. Hyde, T. Igo-Kemenes, 1979, Nucleic Acids Res..

Genetic and metabolic analysis of folate salvage in the human malaria parasite Plasmodium falciparum.

J. E. Hyde, J. Hyde, P. Sims, 2004, Molecular and biochemical parasitology.

Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine‐resistant malaria

J. E. Hyde, T. Triglia, A. Cowman, 1998, The EMBO journal.

Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization

J. E. Hyde, P. Sims, J. Hyde, 1997, Molecular microbiology.

Left-ventricular peak ejection rate, filling rate, and ejection fraction--frame rate requirements at rest and exercise: concise communication.

Michael V. Green, S L Bacharach, G S Johnston, 1979, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Characterisation and translation studies of messenger RNA from the human malaria parasite Plasmodium falciparum and construction of a cDNA library.

J. E. Hyde, I. Hope, A. Osland, 1984, Molecular and biochemical parasitology.

Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy

J. E. Hyde, T. Horii, P F Sims, 1999, Molecular microbiology.

A mutation-specific PCR system to detect sequence variation in the dihydropteroate synthetase gene of Plasmodium falciparum.

J. E. Hyde, P. Sims, D. Brooks, 1995, Molecular and biochemical parasitology.

Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine.

J. E. Hyde, P. Sims, D. Brooks, 1994, European journal of biochemistry.

Proteomics of the human malaria parasite Plasmodium falciparum

J. E. Hyde, J. Hyde, P. Sims, 2006, Expert review of proteomics.

Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?

J. E. Hyde, J. Kublin, A. Cowman, 2001, Trends in parasitology.

Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins.

J. E. Hyde, O. Doumbo, M. Tanner, 1997, Molecular and biochemical parasitology.

Exploring the folate pathway in Plasmodium falciparum.

J. E. Hyde, J. Hyde, 2005, Acta tropica.

The gene for an exported antigen of the malaria parasite Plasmodium falciparum cloned and expressed in Escherichia coli.

J. E. Hyde, I. Hope, J. Scaife, 1985, Nucleic acids research.

Anomalous dinucleotide frequencies in both coding and non-coding regions from the genome of the human malaria parasite Plasmodium falciparum.

J. E. Hyde, P. Sims, J. Hyde, 1987, Gene.

The tubulin genes of the human malaria parasite Plasmodium falciparum, their chromosomal location and sequence analysis of the alpha-tubulin II gene.

J. E. Hyde, S. Holloway, P. Sims, 1990, Molecular and biochemical parasitology.

Folate metabolism in human malaria parasites--75 years on.

J. E. Hyde, J. Hyde, I. Müller, 2013, Molecular and biochemical parasitology.

Antimalarial drugs: modes of action and mechanisms of parasite resistance.

J. E. Hyde, J. Hyde, I. Müller, 2010, Future microbiology.

Vitamin B metabolism in Plasmodium falciparum as a source of drug targets.

J. E. Hyde, C. Wrenger, John E Hyde, 2010, Trends in parasitology.

An atypical orthologue of 6-pyruvoyltetrahydropterin synthase can provide the missing link in the folate biosynthesis pathway of malaria parasites

J. E. Hyde, S. L. Mitchell, A. Blagborough, 2007, Molecular Microbiology.

Characterisation of the gene encoding an unusually divergent TATA-binding protein (TBP) from the extremely A+T-rich human malaria parasite Plasmodium falciparum.

J. E. Hyde, P. Sims, M Read, 1993, Gene.

Expression of α and β tubulin genes during the asexual and sexual blood stages of Plasmodium falciparum

J. E. Hyde, S. Holloway, C. Delves, 1990 .

Molecular characterisation of the enolase gene from the human malaria parasite Plasmodium falciparum. Evidence for ancestry within a photosynthetic lineage.

Kevin E. Hicks, J. E. Hyde, P. Sims, 1994, European journal of biochemistry.

Cloning and characterisation of the rRNA genes from the human malaria parasite Plasmodium falciparum.

J. E. Hyde, G. Langsley, J. Scaife, 1983, Nucleic acids research.

Binding of psoralen derivatives to DNA and chromatin: influence of the ionic environment on dark binding and photoreactivity.

J. E. Hyde, J. Hearst, J. Hyde, 1978, Biochemistry.

The photoaddition of trimethylpsoralen to Drosophila melanogaster nuclei: a probe for chromatin substructure.

J. E. Hyde, J. Hearst, J. Hyde, 1977, Biochemistry.

A photochemical characterisation of reactions of psoralen derivatives with DNA.

J. E. Hyde, J. Hearst, H. Rapoport, 1982 .

Drug‐resistant malaria − an insight

J. E. Hyde, J. Hyde, 2007, The FEBS journal.

A modified in vitro sulfadoxine susceptibility assay for Plasmodium falciparum suitable for investigating Fansidar resistance

J. E. Hyde, P. Sims, J. Hyde, 1997, Parasitology.

The dihydrofolate reductase-thymidylate synthetase gene in the drug resistance of malaria parasites.

J. E. Hyde, J. Hyde, 1990, Pharmacology & therapeutics.

Characterization of three genes encoding enzymes of the folate biosynthetic pathway in Plasmodium falciparum

J. E. Hyde, P. Sims, J. Hyde, 2001, Parasitology.

Glycolytic pathway of the human malaria parasite Plasmodium falciparum: primary sequence analysis of the gene encoding 3-phosphoglycerate kinase and chromosomal mapping studies.

J. E. Hyde, S. Holloway, P. Sims, 1991, Gene.

Isolation of alpha-tubulin genes from the human malaria parasite, Plasmodium falciparum: sequence analysis of alpha-tubulin.

J. E. Hyde, S. Holloway, P. Sims, 1989, Molecular microbiology.

Histones F2a1 and F3 interact reversibly and cooperatively with DNA to form an equimolar complex in chromatin

J. E. Hyde, I. O. Walker, J. Hyde, 1975, FEBS letters.

The application of ESR to chromatin. Spin-labelling of the histone H3 cysteine residues in situ.

J. E. Hyde, I. O. Walker, 1977, Biochimica et biophysica acta.

Covalent cross‐linking of histones in chromatin

J. E. Hyde, I. O. Walker, J. Hyde, 1975, FEBS letters.

Evidence for immunological cross-reaction between sporozoites and blood stages of a human malaria parasite

J. E. Hyde, I. Hope, J. Scaife, 1984, Nature.

Processing, polymorphism, and biological significance of P190, a major surface antigen of the erythrocytic forms of Plasmodium falciparum.

J. E. Hyde, I. Hope, A. Osland, 1984, Molecular and biochemical parasitology.

Mechanisms of resistance of Plasmodium falciparum to antimalarial drugs.

J. E. Hyde, John E Hyde, J. Hyde, 2002, Microbes and infection.

Urine sediment analysis by the Yellow IRIS automated urinalysis workstation.

J. E. Hyde, D. Karcher, D. Wilkinson, 1987, American journal of clinical pathology.

Dynamic subcellular localization of isoforms of the folate pathway enzyme serine hydroxymethyltransferase (SHMT) through the erythrocytic cycle of Plasmodium falciparum

J. E. Hyde, S. L. Mitchell, J. Hyde, 2010, Malaria Journal.

Rational drug design approach for overcoming drug resistance: application to pyrimethamine resistance in malaria.

M Read, J. E. Hyde, W. Sirawaraporn, 1998, Journal of medicinal chemistry.

Comparative folate metabolism in humans and malaria parasites (part II): activities as yet untargeted or specific to Plasmodium.

J. E. Hyde, A. Nzila, K. Marsh, 2005, Trends in parasitology.

On malaria and the cell cycle.

J. E. Hyde, J. Hyde, M. Read, 1997, Parasitology today.

Microtubular organization visualized by immunofluorescence microscopy during erythrocytic schizogony in Plasmodium falciparum and investigation of post-translational modifications of parasite tubulin

J. E. Hyde, K. Gull, S. Holloway, 1993, Parasitology.

Major surface antigen gene of a human malaria parasite cloned and expressed in bacteria

J. E. Hyde, I. Hope, J. Stocker, 1984, Nature.

Rapid positive selection of stable integrants following transfection of Plasmodium falciparum.

J. E. Hyde, J. Hyde, P. Sims, 2002, Molecular and biochemical parasitology.

Drug-resistant malaria.

J. E. Hyde, J. Hyde, 2005, Trends in parasitology.

6-Pyruvoyltetrahydropterin Synthase Paralogs Replace the Folate Synthesis Enzyme Dihydroneopterin Aldolase in Diverse Bacteria

J. E. Hyde, V. de Crécy-Lagard, A. Hanson, 2009, Journal of bacteriology.

Plasmodium falciparum: a paradigm for alternative folate biosynthesis in diverse microorganisms?

J. E. Hyde, V. de Crécy-Lagard, A. Hanson, 2008, Trends in parasitology.

Functional identification of orthologous genes encoding pterin recycling activity in Plasmodium falciparum and Toxoplasma gondii.

J. E. Hyde, A. Hanson, J. Hyde, 2006, Molecular and biochemical parasitology.

Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy.

J. E. Hyde, A. Nzila, K. Marsh, 2005, Trends in parasitology.

Transfection studies to explore essential folate metabolism and antifolate drug synergy in the human malaria parasite Plasmodium falciparum

J. E. Hyde, J. Hyde, P. Sims, 2004, Molecular microbiology.

Transcriptional analysis of genes encoding enzymes of the folate pathway in the human malaria parasite Plasmodium falciparum

J. E. Hyde, J. Hyde, P. Sims, 2002, Molecular microbiology.

The molecular basis of sulfonamide resistance in Toxoplasma gondii and implications for the clinical management of toxoplasmosis.

J. E. Hyde, E. Guy, J. Hyde, 2002, The Journal of infectious diseases.

A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria.

J. E. Hyde, C. Plowe, P. Sims, 2001, Molecular and biochemical parasitology.

Isolation and molecular characterization of the bifunctional hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase gene from Toxoplasma gondii.

J. E. Hyde, P. Sims, C. Delves, 1997, Molecular and biochemical parasitology.

Protocols in molecular parasitology.

J. E. Hyde, J. Hyde, 1993, Methods in molecular biology.

Characterisation of exogenous folate transport in Plasmodium falciparum

J. E. Hyde, J. Hyde, P. Sims, 2007, Molecular and biochemical parasitology.

Prevalence of Toxoplasma gondii in commercial meat products as monitored by polymerase chain reaction--food for thought?

J. E. Hyde, Damian Marlee, J. Hyde, 2002, International journal for parasitology.

Molecular evidence for multiple Toxoplasma gondii infections in individual patients in England and Wales: public health implications.

J. E. Hyde, K. Roberts, E. Guy, 2003, International journal for parasitology.

Green roots of malaria.

J. E. Hyde, P. Sims, J. Hyde, 1994, Parasitology today.

Characterisation of the bifunctional dihydrofolate synthase–folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition

J. E. Hyde, A. Nzila, J. Coward, 2010, Molecular and biochemical parasitology.

Antifolate resistance in Africa and the 164-dollar question.

J. E. Hyde, J. Hyde, 2008, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Aspects of pyrimethamine resistance in Plasmodium falciparum.

J. E. Hyde, D. Walliker, J. Scaife, 1989 .