Masoud Vedadi

发表

SDR goes SGC: A structural genomics initiative

James E. Bray, Brian D. Marsden, Udo Oppermann, 2006 .

Protein production: feeding the crystallographers and NMR spectroscopists

Cheryl H. Arrowsmith, James D. Friesen, Aled M. Edwards, 2000, Nature Structural Biology.

A Strategy for Modulation of Enzymes in the Ubiquitin System

Brian Raught, Mike Tyers, Sachdev S Sidhu, 2013, Science.

Glyoxylate and Pyruvate Are Antagonistic Effectors of the Escherichia coli IclR Transcriptional Regulator*

Alexey Bochkarev, Vladimir V Lunin, Masoud Vedadi, 2007, Journal of Biological Chemistry.

Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.

Alexey Bochkarev, Wolfram Tempel, Anne Mulichak, 2007, Molecular and biochemical parasitology.

Structural basis for molecular recognition and presentation of histone H3 By WDR5

Alexey Bochkarev, Abdellah Allali-Hassani, Peter Loppnau, 2006, The EMBO journal.

Screening for Ligands Using a Generic and High-Throughput Light-Scattering-Based Assay

Masoud Vedadi, M. Vedadi, D. Awrey, 2006, Journal of biomolecular screening.

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.

Feng Liu, Sun-Chong Wang, Jian Jin, 2011, Nature chemical biology.

Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2

Randy J. Read, Matthieu Schapira, Abdellah Allali-Hassani, 2009, Nucleic acids research.

Prevalent p53 mutants co-opt chromatin pathways to drive cancer growth

Cheryl H. Arrowsmith, Greg Donahue, Ali Shilatifard, 2015, Nature.

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

Matthieu Schapira, James E. Bradner, John R. Engen, 2012, Nature Communications.

Discovery of a Dual PRMT5-PRMT7 Inhibitor.

Matthieu Schapira, Cheryl H Arrowsmith, Peter J Brown, 2015, ACS medicinal chemistry letters.

Small-molecule ligands of methyl-lysine binding proteins.

Jian Jin, Cen Gao, Robert Lam, 2011, Journal of medicinal chemistry.

An allosteric inhibitor of protein arginine methyltransferase 3.

Jian Jin, Matthieu Schapira, Alena Siarheyeva, 2012, Structure.

Data mining crystallization databases: Knowledge‐based approaches to optimize protein crystal screens

Mark Gerstein, Steven Beasley, Masoud Vedadi, 2003, Proteins.

Structural and Chemical Profiling of the Human Cytosolic Sulfotransferases

Rafael Najmanovich, Alexey Bochkarev, Abdellah Allali-Hassani, 2007, PLoS biology.

L3MBTL1 recognition of mono- and dimethylated histones

Abdellah Allali-Hassani, Cheryl H Arrowsmith, Jinrong Min, 2007, Nature Structural &Molecular Biology.

Enzymology and Molecular Biology of Carbonyl Metabolism

James E. Bray, Brian D. Marsden, Udo Oppermann, 2005 .

Correction: Structural and Chemical Profiling of the Human Cytosolic Sulfotransferases

Janet M. Thornton, Abdellah Allali-Hassani, Alexander N. Plotnikov, 2007, PLoS Biology.

Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines.

Anton Simeonov, Feng Liu, Ajit Jadhav, 2010, Journal of medicinal chemistry.

Recognition and Specificity Determinants of the Human Cbx Chromodomains*

Shili Duan, Matthieu Schapira, Cheryl H. Arrowsmith, 2010, The Journal of Biological Chemistry.

Characterization of 14-3-3 Proteins from Cryptosporidium parvum

Wen Hwa Lee, Masoud Vedadi, M. Vedadi, 2011, PloS one.

LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity.

Cheryl H Arrowsmith, Peter J Brown, Mary M Mader, 2018, ACS medicinal chemistry letters.

Bromo-deaza-SAH: a potent and selective DOT1L inhibitor.

Matthieu Schapira, Wenyu Yu, Wolfram Tempel, 2013, Bioorganic & medicinal chemistry.

A chemical toolbox for the study of bromodomains and epigenetic signaling

Shili Duan, Mathieu Lupien, Stefan Knapp, 2018, bioRxiv.

A cellular chemical probe targeting the chromodomains of Polycomb Repressive Complex 1

Nancy Cheng, Su Qin, Bradley M Dickson, 2015, Nature chemical biology.

An Allosteric Inhibitor of the Human Cdc34 Ubiquitin-Conjugating Enzyme

Mike Tyers, Xiaojing Tang, Abdallah Al-Hakim, 2011, Cell.

A chemiluminescence-based method for identification of histone lysine methyltransferase inhibitors.

Anton Simeonov, Abdellah Allali-Hassani, Masoud Vedadi, 2010, Molecular bioSystems.

Structure-Activity Relationship Studies for Enhancer of Zeste Homologue 2 (EZH2) and Enhancer of Zeste Homologue 1 (EZH1) Inhibitors.

Jian Jin, Jamel Meslamani, Cheryl H Arrowsmith, 2016, Journal of medicinal chemistry.

A chemical biology toolbox to study protein methyltransferases and epigenetic signaling

Jian Jin, Matthieu Schapira, Jennifer A. Ward, 2019, Nature Communications.

The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex.

Jun Guo, Kenneth M Comess, Haizhong Zhu, 2017, Nature chemical biology.

Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening.

Matthieu Schapira, Cheryl H Arrowsmith, Peter J Brown, 2016, Journal of medicinal chemistry.

A survey of proteins encoded by non-synonymous single nucleotide polymorphisms reveals a significant fraction with altered stability and activity.

Matthieu Schapira, Abdellah Allali-Hassani, John Moult, 2009, The Biochemical journal.

Structural Biology of Human H3K9 Methyltransferases

Valérie Campagna-Slater, Matthieu Schapira, Abdellah Allali-Hassani, 2010, PloS one.

Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.

Anton Simeonov, Feng Liu, Ajit Jadhav, 2009, Journal of medicinal chemistry.