Jules C. Hancox

发表

Virtual Catheter Ablation of Target Areas Identified from Image-Based Models of Atrial Fibrillation

Tobias Schaeffter, Robert S. MacLeod, Aditi Roy, 2019, FIMH.

Modelling the Effects of Propafenone on Human Atrial Patho-Electrophysiology Associated With hERG-Linked Short QT Syndrome

Henggui Zhang, Jules C. Hancox, Dominic G. Whittaker, 2018, 2018 Computing in Cardiology Conference (CinC).

Assessing hERG Pore Models As Templates for Drug Docking Using Published Experimental Constraints: The Inactivated State in the Context of Drug Block

Jules C. Hancox, Christopher E. Dempsey, Dominic Wright, 2014, J. Chem. Inf. Model..

Increased Vulnerability of Human Ventricle to Re-entrant Excitation in hERG-linked Variant 1 Short QT Syndrome

Henggui Zhang, Ismail Adeniran, Jules C. Hancox, 2011, PLoS Comput. Biol..

Application of Micro-Computed Tomography With Iodine Staining to Cardiac Imaging, Segmentation, and Computational Model Development

Henggui Zhang, Jonathan C. Jarvis, Jichao Zhao, 2013, IEEE Transactions on Medical Imaging.

Arrhythmogenic substrate for atrial fibrillation: Insights from an integrative computational model of pulmonary veins

Michael A. Colman, Henggui Zhang, Jichao Zhao, 2012, 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

Interactions between Voltage Sensor and Pore Domains in a hERG K+ Channel Model from Molecular Simulations and the Effects of a Voltage Sensor Mutation

Jules C. Hancox, Christopher E. Dempsey, Charlotte K. Colenso, 2013, J. Chem. Inf. Model..

Atrial Heterogeneity Generates Re-entrant Substrate during Atrial Fibrillation and Anti-arrhythmic Drug Action: Mechanistic Insights from Canine Atrial Models

Michael A. Colman, Marta Varela, Jules C. Hancox, 2016, PLoS Comput. Biol..

Progress and Gaps in Understanding the Electrophysiological Properties of Morphologically Normal Cells from the Cardiac atrioventricular Node

Jules C. Hancox, Kathryn H. Yuill, John S. Mitcheson, 2003, Int. J. Bifurc. Chaos.

Heart Block in the Athlete - Role of Ion Channel Remodelling as Studied Using a One-dimensional Computational Model of the Atrioventricular Node

Jue Li, Jules C. Hancox, Mark R. Boyett, 2018, 2018 Computing in Cardiology Conference (CinC).

Modelling the effects of disopyramide on short QT syndrome variant 1 in the human ventricles

Henggui Zhang, Jules C. Hancox, Alan P. Benson, 2016, 2016 Computing in Cardiology Conference (CinC).

Mechanistic Insights to Pro-arrhythmogenesis of Short QT Syndrome Associated with V307L Gene Mutation in Potassium Channel (IKs)

Jules C. Hancox, Sanjay Kharche, Henggui Zhang, 2008 .

Atrial arrhythmogenicity of KCNJ2 mutations in short QT syndrome: Insights from virtual human atria

Henggui Zhang, Jules C. Hancox, Dominic G. Whittaker, 2017, PLoS Comput. Biol..

A New Algorithm to Diagnose Atrial Ectopic Origin from Multi Lead ECG Systems - Insights from 3D Virtual Human Atria and Torso

Erick A. Perez Alday, Michael A. Colman, Philip Langley, 2015, PLoS Comput. Biol..

In silico investigation of short QT syndrome-linked potassium channel mutations on electro-mechanical function of human atrial cells

Michael A. Colman, Henggui Zhang, Jules C. Hancox, 2015, 2015 Computing in Cardiology Conference (CinC).

The efficacy of class III anti-arrhythmic drugs in 3D canine atrial models: Is the blockade of IKCa pro- or anti-arrhythmic?

Marta Varela, Jules C. Hancox, Oleg V. Aslanidi, 2017, 2017 Computing in Cardiology (CinC).

Reciprocal interaction between IK1 and If in biological pacemakers: A simulation study

Kuanquan Wang, Jules C. Hancox, Yacong Li, 2020, bioRxiv.

Simulation of atrioventricular nodal reentry using detailed anatomical and action potential models

Jules C. Hancox, Halina Dobrzynski, Jue Li, 2008 .

Action potential clamp and chloroquine sensitivity of mutant Kir2.1 channels responsible for variant 3 short QT syndrome

Henggui Zhang, Jules C. Hancox, Mark J. McPate, 2009, Journal of molecular and cellular cardiology.

Effects of Persistent Atrial Fibrillation-Induced Electrical Remodeling on Atrial Electro-Mechanics – Insights from a 3D Model of the Human Atria

Henggui Zhang, Jianqiao Ye, Ismail Adeniran, 2015, PloS one.

In silico investigation of the short QT syndrome, using human ventricle models incorporating electromechanical coupling

Henggui Zhang, Ismail Adeniran, Jules C. Hancox, 2013, Front. Physiol..

A method for isolating rabbit atrioventricular node myocytes which retain normal morphology and function.

Jules C. Hancox, C. O. Lee, A. Levi, 1993, The American journal of physiology.

hERG Potassium Channel Blockade by the HCN Channel Inhibitor Bradycardic Agent Ivabradine

Jules C. Hancox, Christopher E. Dempsey, John S. Mitcheson, 2015, Journal of the American Heart Association.

42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Michael A. Colman, Bruce H. Smaill, Jichao Zhao, 2019, IEEE Transactions on Medical Imaging.

Pro-arrhythmic effects of atrial fibrillation-induced electrical remodelling- insights from 3D virtual human atria.

Michael A. Colman, Henggui Zhang, Jules C. Hancox, 2013 .

Gain-of-function in Kir2.1 and its effects on atrial fibrillation in homogeneous virtual human atrial tissue: a computer simulation study

Jules C. Hancox, Sanjay Kharche, Clifford J. Garratt, 2006 .

Heterogeneous and anisotropic integrative model of pulmonary veins: computational study of arrhythmogenic substrate for atrial fibrillation

Michael A. Colman, Henggui Zhang, Bruce H. Smaill, 2013, Interface Focus.

Recent progress in multi-scale models of the human atria

Erick A. Perez Alday, Michael A. Colman, Henggui Zhang, 2014 .

SHORT COMMUNICATION PLATEAU POTENTIALS IN AN INSECT MOTONEURONE CAN BE DRIVEN BY SYNAPTIC STIMULATION

Jules C. Hancox, J. Hancox, M. Pitman, 1993 .

Evolution and pharmacological modulation of the arrhythmogenic wave dynamics in canine pulmonary vein model

Michael A. Colman, Henggui Zhang, Marta Varela, 2014, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Characteristics of single cells isolated from the atrioventricular node of the adult guinea-pig heart.

Jules C. Hancox, Kathryn H. Yuill, J. Hancox, 2002, Pflügers Archiv.

Characteristics of the delayed rectifier K current compared in myocytes isolated from the atrioventricular node and ventricle of the rabbit heart

Jules C. Hancox, J. Hancox, F. Howarth, 1996, Pflügers Archiv.

The N588K-HERG K+ channel mutation in the ‘short QT syndrome’: Mechanism of gain-in-function determined at 37 °C

Jules C. Hancox, Harry J. Witchel, Mark J. McPate, 2005 .