Robert A. Domaoal

发表

Discovery of Wild-Type and Y181C Mutant Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors Using Virtual Screening with Multiple Protein Structures

William L. Jorgensen, Julian Tirado-Rives, Karen S. Anderson, 2009, J. Chem. Inf. Model..

Eastern extension of azoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase; cyano group alternatives.

William L. Jorgensen, Karen S. Anderson, Robert A. Domaoal, 2010, Bioorganic & medicinal chemistry letters.

Efficient discovery of potent anti-HIV agents targeting the Tyr181Cys variant of HIV reverse transcriptase.

William L. Jorgensen, Karen S. Anderson, Robert A. Domaoal, 2011, Journal of the American Chemical Society.

Optimization of azoles as anti-human immunodeficiency virus agents guided by free-energy calculations.

William L. Jorgensen, Julian Tirado-Rives, Karen S. Anderson, 2008, Journal of the American Chemical Society.

K65R and K65A substitutions in HIV-1 reverse transcriptase enhance polymerase fidelity by decreasing both dNTP misinsertion and mispaired primer extension efficiencies.

Robert A. Domaoal, K. Anderson, S. Garforth, 2010, Journal of molecular biology.

Quasi-Biomimetic Ring Contraction Catalyzed by a Cysteine-Based Nucleophile: Total Synthesis of Sch-642305, Some Analogs and their Putative anti-HIV Activities.

Scott J. Miller, Robert A. Domaoal, K. Anderson, 2011, Chemical science.

Mechanistic and Kinetic Differences between Reverse Transcriptases of Vpx Coding and Non-coding Lentiviruses*

Robert A. Domaoal, R. Schinazi, G. Lenzi, 2015, The Journal of Biological Chemistry.

An Integrated Biological Approach to Guide the Development of Metal-Chelating Inhibitors of Influenza Virus PA Endonuclease

Robert A. Domaoal, L. Naesens, Baek Kim, 2015, Molecular Pharmacology.

Computationally-guided optimization of a docking hit to yield catechol diethers as potent anti-HIV agents.

William L Jorgensen, Robert A. Domaoal, W. L. Jorgensen, 2011, Journal of medicinal chemistry.

Pre-steady state kinetic analysis of HIV-1 reverse transcriptase for non-canonical ribonucleoside triphosphate incorporation and DNA synthesis from ribonucleoside-containing DNA template.

Robert A. Domaoal, R. Schinazi, Baek Kim, 2015, Antiviral research.

An antibody-recruiting small molecule that targets HIV gp120.

Robert A. Domaoal, K. Anderson, Christopher G. Parker, 2009, Journal of the American Chemical Society.

Resistance Mechanisms to HIV-1 Nucleoside Reverse Transcriptase Inhibitors

Robert A. Domaoal, R. Schinazi, B. Herman, 2017 .

Kinetic variations between reverse transcriptases of viral protein X coding and noncoding lentiviruses

Robert A. Domaoal, R. Schinazi, G. Lenzi, 2014, Retrovirology.

A Comprehensive Approach to Assuring Quality of Laboratory Testing in HIV Surveys: Lessons Learned From the Population-Based HIV Impact Assessment Project

Ernest L. Yufenyuy, Robert A. Domaoal, K. Sleeman, 2021, Journal of acquired immune deficiency syndromes.

Pre-steady-state Kinetic Studies Establish Entecavir 5′-Triphosphate as a Substrate for HIV-1 Reverse Transcriptase*

Robert A. Domaoal, Christopher M. Bailey, R. Siliciano, 2008, Journal of Biological Chemistry.

Structural and biochemical effects of human immunodeficiency virus mutants resistant to non-nucleoside reverse transcriptase inhibitors.

Robert A. Domaoal, L. Demeter, R. A. Domaoal, 2004, The international journal of biochemistry & cell biology.

Discovery of dimeric inhibitors by extension into the entrance channel of HIV-1 reverse transcriptase.

Robert A. Domaoal, W. L. Jorgensen, K. Anderson, 2012, Bioorganic & medicinal chemistry letters.

Optimization of pyrimidinyl- and triazinyl-amines as non-nucleoside inhibitors of HIV-1 reverse transcriptase.

William L Jorgensen, Robert A. Domaoal, Christopher M. Bailey, 2006, Bioorganic & medicinal chemistry letters.

From docking false-positive to active anti-HIV agent.

William L Jorgensen, Cristiano R W Guimarães, Robert A. Domaoal, 2007, Journal of medicinal chemistry.

Illuminating HIV gp120-Ligand Recognition through Computationally-Driven Optimization of Antibody-Recruiting Molecules.

Markus K. Dahlgren, Robert A. Domaoal, W. L. Jorgensen, 2014, Chemical science.