Edward G Lakatta

发表

Computer algorithms for automated detection and analysis of local Ca2+ releases in spontaneously beating cardiac pacemaker cells

Kenta Tsutsui, Alexander V Maltsev, Sean P Parsons, 2017, PloS one.

&bgr;-Adrenergic Stimulation Modulates Ryanodine Receptor Ca2+ Release During Diastolic Depolarization to Accelerate Pacemaker Activity in Rabbit Sinoatrial Nodal Cells

Edward G Lakatta, E. Lakatta, Tatiana M Vinogradova, 2002, Circulation research.

Aging-associated cardiovascular changes and their relationship to heart failure.

Edward G Lakatta, E. Lakatta, J. Strait, 2012, Heart failure clinics.

Metabolic syndrome amplifies the age-associated increases in vascular thickness and stiffness.

Reubin Andres, Edward G Lakatta, E. Lakatta, 2003, Journal of the American College of Cardiology.

Nature Genetics Advance Online Publication Genetic Association Study of Qt Interval Highlights Role for Calcium Signaling Pathways in Myocardial Repolarization

Michael J Ackerman, Christian Gieger, Thomas Meitinger, 2022 .

Rebuttal: what I(f) the shoe doesn't fit? "The funny current has a major pacemaking role in the sinus node".

Edward G Lakatta, Victor A Maltsev, E. Lakatta, 2012, Heart rhythm.

Arterial aging is risky.

Edward G Lakatta, E. Lakatta, 2008, Journal of applied physiology.

Genome-wide association analysis identifies multiple loci related to resting heart rate.

Christian Gieger, Thomas Meitinger, Henry Völzke, 2010, Human molecular genetics.

Arterial aging: is it an immutable cardiovascular risk factor?

Edward G Lakatta, E. Lakatta, A. Scuteri, 2005, Hypertension.

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Christian Gieger, Thomas Meitinger, Inês Barroso, 2009, Nature Genetics.

Characterization of volumetric flow rate waveforms at the carotid bifurcations of older adults

David A Steinman, Yiemeng Hoi, Edward G Lakatta, 2010, Physiological measurement.

Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects.

Yoav Ben-Shlomo, Telmo Pereira, Stephane Laurent, 2014, Journal of the American College of Cardiology.

Pulse wave velocity is an independent predictor of the longitudinal increase in systolic blood pressure and of incident hypertension in the Baltimore Longitudinal Study of Aging.

Luigi Ferrucci, Edward G Lakatta, L. Ferrucci, 2008, Journal of the American College of Cardiology.

Ca2+‐dependent components of inactivation of unitary cardiac L‐type Ca2+ channels

Michael D Stern, Edward G Lakatta, E. Lakatta, 2010, The Journal of physiology.

Beat-to-beat Ca(2+)-dependent regulation of sinoatrial nodal pacemaker cell rate and rhythm.

Yael Yaniv, Michael D Stern, Edward G Lakatta, 2011, Journal of molecular and cellular cardiology.

Metabolic syndrome across Europe: Different clusters of risk factors

Henry Völzke, James Strait, Francesco Cucca, 2015, European journal of preventive cardiology.

Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.

Leonid Peshkin, Stuart Maudsley, Michel Bernier, 2014, Cell metabolism.

Central or peripheral systolic or pulse pressure: which best relates to target organs and future mortality?

Hao-Min Cheng, Pesus Chou, Edward G Lakatta, 2009, Journal of hypertension.

Perspectives on mammalian cardiovascular aging: humans to molecules.

Edward G Lakatta, E. Lakatta, S. Sollott, 2002, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

Arterial aging and subclinical arterial disease are fundamentally intertwined at macroscopic and molecular levels.

Edward G Lakatta, E. Lakatta, S. Najjar, 2009, The Medical clinics of North America.

52 Genetic Loci Influencing Myocardial Mass.

Christian Gieger, Thomas Meitinger, Manolis Kellis, 2016, Journal of the American College of Cardiology.

Synergism of coupled subsarcolemmal Ca2+ clocks and sarcolemmal voltage clocks confers robust and flexible pacemaker function in a novel pacemaker cell model.

Edward G Lakatta, Victor A Maltsev, E. Lakatta, 2009, American journal of physiology. Heart and circulatory physiology.

Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part III: Cellular and Molecular Clues to Heart and Arterial Aging

Edward G Lakatta, E. Lakatta, 2003, Circulation.

Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk

Christian Gieger, Xiaofeng Zhu, Paolo Vineis, 2011, Nature.

Arterial-ventricular coupling: mechanistic insights into cardiovascular performance at rest and during exercise.

Edward G Lakatta, E. Lakatta, S. Najjar, 2008, Journal of applied physiology.

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease.

Daniel Levy, Edward G Lakatta, D. Levy, 2003, Circulation.

Subtype-specific beta-adrenoceptor signaling pathways in the heart and their potential clinical implications.

Richard Bond, Heping Cheng, Edward G Lakatta, 2004, Trends in pharmacological sciences.

Wave Reflection and Arterial Stiffness in the Prediction of 15-Year All-Cause and Cardiovascular Mortalities: A Community-Based Study

Hao-Min Cheng, Shih-Hsien Sung, Pesus Chou, 2010, Hypertension.

What keeps us ticking: a funny current, a calcium clock, or both?

Dario DiFrancesco, Edward G Lakatta, E. Lakatta, 2009, Journal of molecular and cellular cardiology.

A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker.

Edward G Lakatta, Victor A Maltsev, E. Lakatta, 2010, Circulation research.

β-Adrenergic signaling accelerates and synchronizes cardiac ryanodine receptor response to a single L-type Ca2+ channel

Shu-Hua Bai, Heping Cheng, Edward G Lakatta, 2009, Proceedings of the National Academy of Sciences.

The emergence of a general theory of the initiation and strength of the heartbeat.

Edward G Lakatta, Victor A Maltsev, E. Lakatta, 2006, Journal of pharmacological sciences.

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Christian Gieger, Gonçalo Abecasis, He Gao, 2018, Nature Genetics.

Prognostic significance of mechanical biomarkers derived from pulse wave analysis for predicting long-term cardiovascular mortality in two population-based cohorts.

Wen-Harn Pan, Hao-Min Cheng, Shih-Hsien Sung, 2016, International journal of cardiology.

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease.

Daniel Levy, Edward G Lakatta, D. Levy, 2003, Circulation.

Diastolic calcium release controls the beating rate of rabbit sinoatrial node cells: numerical modeling of the coupling process.

Michael D Stern, Edward G Lakatta, Victor A Maltsev, 2004, Biophysical journal.

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Christian Gieger, Gonçalo Abecasis, He Gao, 2017, bioRxiv.

On the shape of the common carotid artery with implications for blood velocity profiles

David A Steinman, Amir Manbachi, Yiemeng Hoi, 2011, Physiological measurement.

A quantitative and validated SAGE transcriptome reference for adult mouse heart.

Michael D Stern, Edward G Lakatta, E. Lakatta, 2002, Genomics.

The funny current in the context of the coupled-clock pacemaker cell system.

Edward G Lakatta, Victor A Maltsev, E. Lakatta, 2012, Heart rhythm.

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Claude Bouchard, William Wheeler, Peter Kraft, 2014 .

Central Role for the Cardiotonic Steroid Marinobufagenin in the Pathogenesis of Experimental Uremic Cardiomyopathy

Deepak Malhotra, Samer Khouri, Edward G Lakatta, 2006, Hypertension.