Jos Jonkers

发表

Identification of Networks of Co-Occurring, Tumor-Related DNA Copy Number Changes Using a Genome-Wide Scoring Approach

Marcel J. T. Reinders, Lodewyk F. A. Wessels, David J. Adams, 2010, PLoS Comput. Biol..

Abstract 1296: CanPathPro—development of a platform for predictive pathway modelling using genetically engineered mouse models

Julio R. Banga, Jan Hasenauer, Bodo M. H. Lange, 2018 .

Patient-derived xenograft models: an emerging platform for translational cancer research.

Manuel Hidalgo, Eva Budinská, Carlos Caldas, 2014, Cancer discovery.

Erratum: Interrogating open issues in cancer medicine with patient-derived xenografts

Hans Clevers, Manuel Hidalgo, Eva Budinská, 2017, Nature Reviews Cancer.

Genetically engineered mouse models of PI3K signaling in breast cancer

Jos Jonkers, J. Jonkers, S. Klarenbeek, 2013, Molecular oncology.

Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues.

Jos Jonkers, Ernesto Bockamp, Steffen Schmitt, 2007, Physiological genomics.

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.

Jos Jonkers, Robert D Cardiff, Bastiaan Evers, 2006, Cancer cell.

MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer

Jos Jonkers, Lodewyk Wessels, L. Wessels, 2007, Nature Genetics.

A high-throughput functional complementation assay for classification of BRCA1 missense variants.

Peter Bouwman, Jos Jonkers, I. van der Heijden, 2013, Cancer discovery.

Genetically engineered mouse models in oncology research and cancer medicine

Jos Jonkers, J. Jonkers, K. D. de Visser, 2016, EMBO molecular medicine.

A self-assembled multimodal complex for combined pre- and intraoperative imaging of the sentinel lymph node

Jos Jonkers, Tessa Buckle, Fijs W B van Leeuwen, 2010, Nanotechnology.

BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance

Hans Clevers, Jos Jonkers, Piet Borst, 2017, Nature Methods.

Computational identification of insertional mutagenesis targets for cancer gene discovery

Johann de Jong, Jeroen de Ridder, David J. Adams, 2011, Nucleic acids research.

Interrogating open issues in cancer precision medicine with patient-derived xenografts

Hans Clevers, Manuel Hidalgo, Eva Budinská, 2017, Nature Reviews Cancer.

Mice Deficient for All PIM Kinases Display Reduced Body Size and Impaired Responses to Hematopoietic Growth Factors

Jos Jonkers, Anton Berns, Martijn Nawijn, 2004, Molecular and Cellular Biology.

The Shieldin complex mediates 53BP1-dependent DNA repair

Anne-Claude Gingras, Zhen-Yuan Lin, Jos Jonkers, 2018, Nature.

A highly efficient ligand‐regulated Cre recombinase mouse line shows that LoxP recombination is position dependent

Jos Jonkers, Anton Berns, A. Berns, 2001, EMBO reports.

BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.

Peter Bouwman, Christiaan Klijn, Jos Jonkers, 2011, Cancer cell.

CopywriteR: DNA copy number detection from off-target sequence data

Jos Jonkers, Ekaterina Nevedomskaya, Bauke Ylstra, 2015, Genome Biology.

The use of mass spectrometry imaging to predict treatment response of patient-derived xenograft models of triple-negative breast cancer.

Jos Jonkers, Ron M A Heeren, Gert B. Eijkel, 2015, Journal of proteome research.

Proteomics of Mouse BRCA1-deficient Mammary Tumors Identifies DNA Repair Proteins with Potential Diagnostic and Prognostic Value in Human Breast Cancer*

Marc Warmoes, Jos Jonkers, Thang V Pham, 2012, Molecular & Cellular Proteomics.

Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.

Shridar Ganesan, Jos Jonkers, Piet Borst, 2013, Cancer discovery.

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

David J. Adams, Jos Jonkers, Ji-Ying Song, 2018, BMC Bioinformatics.

Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland

Jos Jonkers, Hatice Yücel, I. Huijbers, 2016, Genes & development.

Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers

Jos Jonkers, S. Linn, J. Jonkers, 2011, Cellular and Molecular Life Sciences.

Correction to: Landscape of somatic mutations in 560 breast cancer whole-genome sequences (Nature, (2016), 534, 7605, (47-54), 10.1038/nature17676)

Ville Mustonen, Sung-Min Ahn, Stefania Tommasi, 2019 .

Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer

Jos Jonkers, Piet Borst, Marina Pajic, 2007, Proceedings of the National Academy of Sciences.

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

Peter Bouwman, Jiri Bartek, Kees Jalink, 2015, Nature.

Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.

Jeroen de Ridder, Jos Jonkers, Konstantin Matentzoglu, 2010, Cancer research.

Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice.

Jos Jonkers, Anton Berns, A. Berns, 2002, Cancer research.

Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data

Jeroen de Ridder, Christiaan Klijn, Jos Jonkers, 2008, Nucleic acids research.

A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites

Jos Jonkers, Louise van der Weyden, David J Adams, 2009, Nature Protocols.

The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance

Peter Bouwman, Jos Jonkers, J. Jonkers, 2012, Nature Reviews Cancer.