Joseph Schlessinger

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Exposing the Obscured Influence of State-Controlled Media: A Causal Estimation of Influence Between Media Outlets Via Quotation Propagation pdf

Edward K. Kao, Richard Bennet, Joseph Schlessinger, 2022, ArXiv.

Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin

Steven Gygi, Noah Dephoure, Joseph Schlessinger, 2011, Molecular biology of the cell.

Switching Signals On or Off by Receptor Dimerization

Arthur Weiss, Joseph Schlessinger, J. Schlessinger, 1998, Cell.

FGFR3-targeted mAb therapy for bladder cancer and multiple myeloma.

Joseph Schlessinger, J. Schlessinger, Yaron Hadari, 2009, The Journal of clinical investigation.

On the nature of low- and high-affinity EGF receptors on living cells.

Peter Klein, Joseph Schlessinger, I. Lax, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

Charis Eng, Zhou Songyang, Kermit L. Carraway, 1995, Nature.

Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells

Joseph Schlessinger, T. Boggon, I. Lax, 2010, Proceedings of the National Academy of Sciences.

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

Hermona Soreq, Towia A. Libermann, Joseph Schlessinger, 1985, Nature.

Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor

Joseph Schlessinger, I. Lax, J. Schlessinger, 2007, Cell.

Structure of a heparin-linked biologically active dimer of fibroblast growth factor

Wayne A. Hendrickson, Michael Jaye, Joseph Schlessinger, 1998, Nature.

Asymmetric tyrosine kinase arrangements in activation or autophosphorylation of receptor tyrosine kinases

Joseph Schlessinger, J. Schlessinger, J. Bae, 2010, Molecules and cells.

Novel recognition mode between Vav and Grb2 SH3 domains

Kenji Ogura, Koji Nagata, Fuyuhiko Inagaki, 2001, The EMBO journal.

Common and Distinct Elements in Cellular Signaling via EGF and FGF Receptors

Joseph Schlessinger, J. Schlessinger, 2004, Science.

Data publication with the structural biology data grid supports live analysis

Oleg V. Tsodikov, Stephen C. Blacklow, Amedeo Caflisch, 2016, Nature Communications.

Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer.

Guoping Cai, David L Rimm, Soldano Ferrone, 2017, Cancer discovery.

Structure of the FGF Receptor Tyrosine Kinase Domain Reveals a Novel Autoinhibitory Mechanism

Joseph Schlessinger, S. Hubbard, J. Schlessinger, 1996, Cell.

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

Kam Y. J. Zhang, James Tsai, Nikolas K. Haass, 2008, Proceedings of the National Academy of Sciences.

The Docking Protein Gab1 Is an Essential Component of an Indirect Mechanism for Fibroblast Growth Factor Stimulation of the Phosphatidylinositol 3-Kinase/Akt Antiapoptotic Pathway

Walter Birchmeier, Joseph Schlessinger, W. Birchmeier, 2004, Molecular and Cellular Biology.

Local aggregation of hormone–receptor complexes is required for activation by epidermal growth factor

Pedro Cuatrecasas, Joseph Schlessinger, P. Cuatrecasas, 1979, Nature.

Spatial control of EGF receptor activation by reversible dimerization on living cells

Derek Toomre, Ira Mellman, Joseph Schlessinger, 2010, Nature.

Crystal Structures of Two FGF-FGFR Complexes Reveal the Determinants of Ligand-Receptor Specificity

Joseph Schlessinger, S. Hubbard, J. Schlessinger, 2000, Cell.

A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design

Kam Y. J. Zhang, Chao Zhang, Kam Y J Zhang, 2005, Nature Biotechnology.

PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation

Ivan Dikic, Joseph Schlessinger, I. Lax, 1994, Current Biology.

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway

Michael Karin, Nanxin Li, Joseph Schlessinger, 1994, Cell.

Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction.

Cristina M Furdui, Joseph Schlessinger, K. Anderson, 2006, Molecular cell.

The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function.

Peter Klein, Joseph Schlessinger, I. Lax, 2004, Proceedings of the National Academy of Sciences of the United States of America.

A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases.

Kam Y. J. Zhang, Chao Zhang, Gideon Bollag, 2004, Molecular cell.

Signal transduction by receptors with tyrosine kinase activity

Joseph Schlessinger, A. Ullrich, J. Schlessinger, 1990, Cell.

The biochemical response of the heart to hypertension and exercise.

Elliot L Elson, Joseph Schlessinger, E. Elson, 2004, Trends in biochemical sciences.

SH2 and PTB Domains in Tyrosine Kinase Signaling

Joseph Schlessinger, J. Schlessinger, M. Lemmon, 2003, Science's STKE.

A structure-based model for ligand binding and dimerization of EGF receptors.

Peter Klein, Joseph Schlessinger, J. Schlessinger, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Ligand-Induced, Receptor-Mediated Dimerization and Activation of EGF Receptor

Joseph Schlessinger, J. Schlessinger, 2002, Cell.

A putative molecular-activation switch in the transmembrane domain of erbB2

Sarel J. Fleishman, Nir Ben-Tal, Joseph Schlessinger, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The EGF Receptor Provides an Essential Survival Signal for SOS-Dependent Skin Tumor Development

Fiona M. Watt, Alexander Fleischmann, Axel Behrens, 2000, Cell.

The Dark Side of Cell Signaling: Positive Roles for Negative Regulators

Anatoly Kiyatkin, Joseph Schlessinger, A. Kiyatkin, 2016, Cell.

Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity.

Robert J Linhardt, Shaun K Olsen, Fuming Zhang, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Discovery of novel fibroblast growth factor receptor 1 kinase inhibitors by structure-based virtual screening.

William L Jorgensen, Joseph Schlessinger, W. L. Jorgensen, 2010, Journal of medicinal chemistry.

A Novel Positive Feedback Loop Mediated by the Docking Protein Gab1 and Phosphatidylinositol 3-Kinase in Epidermal Growth Factor Receptor Signaling

Joseph Schlessinger, J. Schlessinger, M. Falasca, 2000, Molecular and Cellular Biology.