Jon Clardy

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A Machine Learning Bioinformatics Method to Predict Biological Activity from Biosynthetic Gene Clusters

Allison S. Walker, Jon Clardy, J. Clardy, 2021, J. Chem. Inf. Model..

Cyclomarins A−C, New Antiinflammatory Cyclic Peptides Produced by a Marine Bacterium (Streptomyces sp.)

William Fenical, Paul R. Jensen, Jon Clardy, 1999 .

Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis.

Dong-Chan Oh, Michael Poulsen, Jon Clardy, 2009, Nature chemical biology.

Atomic Structure of the Rapamycin Human Immunophilin FKBP-12 Complex

Stuart L. Schreiber, Robert F. Standaert, G. D. Van Duyne, 1991 .

Lassomycin, a ribosomally synthesized cyclic peptide, kills mycobacterium tuberculosis by targeting the ATP-dependent protease ClpC1P1P2.

Alfred Goldberg, Jon Clardy, Clarissa S Sit, 2014, Chemistry & biology.

The evolution of gene collectives: How natural selection drives chemical innovation

Christopher T. Walsh, Michael A. Fischbach, Jon Clardy, 2008, Proceedings of the National Academy of Sciences.

Diarrhetic shellfish toxins

Jon Clardy, J. Clardy, T. Yasumoto, 1985 .

Bacterial symbionts and natural products.

Jason M Crawford, Jon Clardy, J. Crawford, 2011, Chemical communications.

A Sexually Conditioned Switch of Chemosensory Behavior in C. elegans

Naoko Sakai, Ryo Iwata, Yuichi Iino, 2013, PloS one.

Structure of Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor.

Darrell E Hurt, Jon Clardy, J. Widom, 2006, Acta crystallographica. Section D, Biological crystallography.

Guanacastepene, a fungal-derived diterpene antibiotic with a new carbon skeleton

Sean F. Brady, Jon Clardy, J. Clardy, 2000 .

A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells.

Pamela A. Silver, William R. Sellers, Jon Clardy, 2003, Cancer cell.

Differential analysis of 2D NMR spectra: new natural products from a pilot-scale fungal extract library.

Jon Clardy, J. Clardy, S. Krasnoff, 2007, Angewandte Chemie.

Crystal and molecular structure of dynemicin A: a novel 1,5-diyn-3-ene antitumor antibiotic

Toshikazu Oki, Hiroaki Ohkuma, Takashi Tsuno, 1990 .

d-Amino Acids Trigger Biofilm Disassembly

Roberto Kolter, Jon Clardy, R. Losick, 2010, Science.

Dynamics of Snake-like Swarming Behavior of Vibrio alginolyticus.

Hunter L. Elliott, Thomas Böttcher, Jon Clardy, 2016, Biophysical journal.

Palmitoylputrescine, an antibiotic isolated from the heterologous expression of DNA extracted from bromeliad tank water.

Jon Clardy, Sean F Brady, 2004, Journal of natural products.

FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells

Jon Clardy, E. Lam, J. Clardy, 2008, Molecular Cancer Therapeutics.

Small-molecule Inhibitors of Pseudomonas aeruginosa Biofilm Development

Jon Clardy, J. Clardy, Lauren M Junker, 2012, The Meducator.

Two Chemoreceptors Mediate Developmental Effects of Dauer Pheromone in C. elegans

Kazushige Touhara, Jon Clardy, R. Butcher, 2009, Science.

Unequivocal determination of complex molecular structures using anisotropic NMR measurements

Josep Saurí, R Thomas Williamson, Gary E Martin, 2017, Science.

Atomic Structure of the Trypsin-Aeruginosin 98-B Complex

Jon Clardy, J. Clardy, B. Sandler, 1998 .

Traditional Medicine Collection Tracking System (TM-CTS): a database for ethnobotanically driven drug-discovery programs.

Zhongzhen Zhao, Sean D Erickson, Caroline E Shamu, 2011, Journal of ethnopharmacology.

New antibiotics from bacterial natural products

Michael A Fischbach, Christopher T Walsh, Jon Clardy, 2006, Nature Biotechnology.

Liver-stage malaria parasites vulnerable to diverse chemical scaffolds

Miguel Prudêncio, Jon Clardy, M. Mota, 2012, Proceedings of the National Academy of Sciences.

THE STRUCTURE OF SAXITOXIN

Jon Clardy, J. Springer, J. Clardy, 1975 .

Mating in the Closest Living Relatives of Animals Is Induced by a Bacterial Chondroitinase

Ryan E. Hulett, Jon Clardy, J. Clardy, 2017, Cell.

Structure of the FKBP12-Rapamycin Complex Interacting with Binding Domain of Human FRAP

Stuart L. Schreiber, Jie Chen, Jon Clardy, 1996, Science.

Quorum-Sensing-Regulated Bactobolin Production by Burkholderia thailandensis E264

Mohammad R. Seyedsayamdost, Jon Clardy, E. Greenberg, 2010, Organic letters.

Isolation of Antibiotics Turbomycin A and B from a Metagenomic Library of Soil Microbial DNA

Jo Handelsman, Mark R. Liles, Robert M. Goodman, 2002, Applied and Environmental Microbiology.

Microbial genome mining answers longstanding biosynthetic questions

Jason M Crawford, Jon Clardy, J. Crawford, 2012, Proceedings of the National Academy of Sciences.

Bacterial printing press that regenerates its ink: contact-printing bacteria using hydrogel stamps.

George M Whitesides, Jon Clardy, G. Whitesides, 2005, Langmuir : the ACS journal of surfaces and colloids.

One pathway, many products.

Michael A Fischbach, Jon Clardy, M. Fischbach, 2007, Nature chemical biology.

Total Synthesis of (+)-Octalactins A and B: Unusual Metabolites from a Marine Microbe

Jon Clardy, J. McWilliams, J. Clardy, 1994 .

A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics

Peter Cimermancic, Makedonka Mitreva, Michael A. Fischbach, 2014, Cell.

Cyclomarins A—C, New Antiinflammatory Cyclic Peptides Produced by a Marine Bacterium (Streptomyces sp.).

William Fenical, Paul R. Jensen, Jon Clardy, 2000 .

GABA Modulating Bacteria of the Human Gut Microbiota

Karsten Zengler, Rob Knight, Conor Liston, 2018, Nature Microbiology.

DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS AND THE X-RAY CRYSTAL-STRUCTURES OF THEIR COMPLEXES WITH FKBP12.

Jon Clardy, J. Luengo, L. Rozamus, 1994 .

Long-Chain N-Acyltyrosine Synthases from Environmental DNA

Sean F. Brady, Jon Clardy, J. Clardy, 2004, Applied and Environmental Microbiology.

Variable genetic architectures produce virtually identical molecules in bacterial symbionts of fungus-growing ants

Jon Clardy, Clarissa S Sit, J. Clardy, 2015, Proceedings of the National Academy of Sciences.

Isolation and Structure Determination of Diazonamides A and B, Unusual Cytotoxic Metabolites from the Marine Ascidian Diazona chinensis

William Fenical, Jon Clardy, J. Clardy, 1991 .