Jeffrey W. Smith

发表

Quantitative profiling of protease specificity

Piotr Cieplak, Boris I. Ratnikov, Albert G. Remacle, 2021, PLoS Comput. Biol..

Stochastic Gene Expression in a Single Cell

Jeffrey W. Smith, M. Kaul, B. Yan, .

Optical detection of indocyanine green encapsulated biocompatible poly (lactic-co-glycolic) acid nanoparticles with photothermal optical coherence tomography.

Jeffrey W. Smith, O. McCarty, H. Subhash, 2012, Optics letters.

Stochastic Gene Expression in a Single Cell

Jeffrey W. Smith, M. Kaul, B. Yan, 2022 .

An intrinsic mechanism of secreted protein aging and turnover

Jeffrey W. Smith, J. Marth, W. Yang, 2015, Proceedings of the National Academy of Sciences of the United States of America.

Profiling constitutive proteolytic events in vivo.

Jeffrey W. Smith, G. Salvesen, W. Tao, 2007, The Biochemical journal.

Basis for substrate recognition and distinction by matrix metalloproteinases

Jeffrey W. Smith, A. Godzik, A. Strongin, 2014, Proceedings of the National Academy of Sciences.

Correction: CleavPredict: A Platform for Reasoning about Matrix Metalloproteinases Proteolytic Events

Jeffrey W. Smith, P. Cieplak, M. Kazanov, 2015, PloS one.

Platelet Mimetic Particles for Targeting Thrombi in Flowing Blood

Jeffrey W. Smith, S. Mitragotri, Nishit Doshi, 2012, Advanced materials.

Ligand Binding to Integrins*

Li Zhang, Jeffrey W. Smith, J. Loftus, 2000, The Journal of Biological Chemistry.

Structural determinants of limited proteolysis.

Ying Zhang, Adam Godzik, Piotr Cieplak, 2011, Journal of proteome research.

CleavPredict: A Platform for Reasoning about Matrix Metalloproteinases Proteolytic Events

Piotr Cieplak, Marat D. Kazanov, Boris I. Ratnikov, 2015, PloS one.

Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma

Boris Ratnikov, Jeffrey W. Smith, A. Osterman, 2015, Oncotarget.

Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells

Fabian V. Filipp, Jeffrey W. Smith, A. Osterman, 2012, Pigment cell & melanoma research.

Functional Specialization in Proline Biosynthesis of Melanoma

Jeffrey W. Smith, A. Osterman, M. Kazanov, 2012, PloS one.

Methods for analysis of the integrin ligand binding event.

Jeffrey W. Smith, 2002, Methods in cell biology.

Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system

Jeffrey W. Smith, Hui Xie, Jeffrey W Smith, 2010, Journal of nanobiotechnology.

Functional activation of integrin αvβ3 in tumor cells expressing membrane‐type 1 matrix metalloproteinase

Jeffrey W. Smith, A. Strongin, E. Deryugina, 2000 .

Polymer particle shape independently influences binding and internalization by macrophages.

Samir Mitragotri, Gaurav Sharma, Jeffrey W. Smith, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase.

Jeffrey W. Smith, A. Godzik, A. Strongin, 2006, The Biochemical journal.

Expression and purification of a two-component flaviviral proteinase resistant to autocleavage at the NS2B-NS3 junction region.

Jeffrey W. Smith, A. Strongin, R. Liddington, 2007, Protein expression and purification.

Cleavage preference distinguishes the two-component NS2B-NS3 serine proteinases of Dengue and West Nile viruses.

Jeffrey W. Smith, A. Strongin, M. Lebl, 2007, Biochemical Journal.

The Two-component NS2B-NS3 Proteinase Represses DNA Unwinding Activity of the West Nile Virus NS3 Helicase*

Jeffrey W. Smith, A. Strongin, R. Liddington, 2008, Journal of Biological Chemistry.

Structure-based mutagenesis identifies important novel determinants of the NS2B cofactor of the West Nile virus two-component NS2B-NS3 proteinase.

Jeffrey W. Smith, A. Strongin, R. Liddington, 2008, The Journal of general virology.

Efficient synthetic inhibitors of anthrax lethal factor.

Dawoon Jung, Maurizio Pellecchia, Alex Y Strongin, 2005, Proceedings of the National Academy of Sciences of the United States of America.

High-Throughput Multiplexed Peptide-Centric Profiling Illustrates Both Substrate Cleavage Redundancy and Specificity in the MMP Family.

Piotr Cieplak, David A. Routenberg, Muskan Kukreja, 2015, Chemistry & biology.

Substrate Cleavage Analysis of Furin and Related Proprotein Convertases

Piotr Cieplak, Michal Lebl, Robert Day, 2008, Journal of Biological Chemistry.

S-Nitrosylation of Matrix Metalloproteinases: Signaling Pathway to Neuronal Cell Death

Jiankun Cui, Robert C. Liddington, Stuart A. Lipton, 2002, Science.

Genomic taxonomy boost by lexical clustering

Jeffrey W. Smith, J. Keith, S. Boyd, 2014 .

Central carbon metabolism in the progression of mammary carcinoma

Adam D. Richardson, Jeffrey W. Smith, A. Osterman, 2007, Breast Cancer Research and Treatment.

Matrix Metalloproteinase Proteolysis of the Myelin Basic Protein Isoforms Is a Source of Immunogenic Peptides in Autoimmune Multiple Sclerosis

Piotr Cieplak, Boris I. Ratnikov, Jeffrey W. Smith, 2009, PloS one.

Protein Loop Grafting to Construct a Variant of Tissue-type Plasminogen Activator That Binds Platelet Integrin αIIbβ3(*)

Jeffrey W. Smith, E. Madison, Edwin L. Madison, 1995, The Journal of Biological Chemistry.

αv Integrins mediate adhesion and migration of breast carcinoma cell lines

Vito Quaranta, Carlos F. Barbas, Jeffrey W. Smith, 2004, Clinical & Experimental Metastasis.

Cilengitide Merck.

Jeffrey W. Smith, 2003, Current opinion in investigational drugs.

A Unique Substrate Binding Mode Discriminates Membrane Type 1-Matrix Metalloproteinase ( MT 1-MMP ) from other Matrix Metalloproteinases

Jeffrey W. Smith, A. Godzik, S. Kridel, 2002 .

MT1-MMP Initiates Activation of pro-MMP-2 and Integrin αvβ3 Promotes Maturation of MMP-2 in Breast Carcinoma Cells

Jeffrey W. Smith, A. Strongin, B. Ratnikov, 2001 .

Inflammatory Proprotein Convertase-Matrix Metalloproteinase Proteolytic Pathway in Antigen-presenting Cells as a Step to Autoimmune Multiple Sclerosis*

Jeffrey W. Smith, A. Strongin, Roy M. Williams, 2009, The Journal of Biological Chemistry.

A Biochemical Characterization of the Binding of Osteopontin to Integrins αvβ1 and αvβ5(*)

Jeffrey W. Smith, N. Kovach, J. Hoyer, 1995, The Journal of Biological Chemistry.

The Structural Basis of Integrin—Ligand (RGD) Interaction

Jeffrey W. Smith, 1994 .

A New Model of Dual Interacting Ligand Binding Sites on Integrin αIIbβ3 *

Jeffrey W. Smith, N. Nicholson, D. Hu, 1999, The Journal of Biological Chemistry.

A novel vitronectin receptor integrin (α v β x ) is responsible for distinct adhesive properties of carcinoma cells

Jeffrey W. Smith, V. Quaranta, D. Cheresh, 1989, Cell.

A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids.

Jeffrey W. Smith, J. Sacchettini, S. Sieber, 2017, Bioorganic & medicinal chemistry.

Microwave-assisted fabrication of carbon nanotubes decorated polymeric nano-medical platforms for simultaneous drug delivery and magnetic resonance imaging

Jeffrey W. Smith, E. Snyder, Hui Xie, 2014 .

Mitochondrial p32 Protein Is a Critical Regulator of Tumor Metabolism via Maintenance of Oxidative Phosphorylation

Jeffrey W. Smith, E. Ruoslahti, A. Richardson, 2010, Molecular and Cellular Biology.

Ligand and cation binding are dual functions of a discrete segment of the integrin β 3 subunit: Cation displacement is involved in ligand binding

Jeffrey W. Smith, H. Soule, C. Cierniewski, 1994, Cell.

Ca2+Suppresses Cell Adhesion to Osteopontin by Attenuating Binding Affinity for Integrin αvβ3*

Jeffrey W. Smith, J. Hoyer, D. Hu, 1995, The Journal of Biological Chemistry.

A Redox Site Involved in Integrin Activation*

Jeffrey W. Smith, B. Yan, 2000, The Journal of Biological Chemistry.

Characterization of monoclonal antibodies against integrin αVβ5

Jeffrey W. Smith, I. Stuiver, 1995 .

Redox control of integrin adhesion receptors.

Jeffrey W. Smith, B. Yan, C. Lombardo, 2002, Methods in enzymology.

Targeting Host Cell Furin Proprotein Convertases as a Therapeutic Strategy against Bacterial Toxins and Viral Pathogens*

Jeffrey W. Smith, A. Strongin, R. Liddington, 2007, Journal of Biological Chemistry.

Efficacy of a β-Lactamase Inhibitor Combination for Serious Intra-abdominal Infections

Jeffrey W. Smith, C. Edmiston, D. Trunkey, 1993 .

Probing Chemical and Conformational Differences in the Resting and Active Conformers of Platelet Integrin αIIbβ3 *

Jeffrey W. Smith, B. Yan, D. Hu, 2000, The Journal of Biological Chemistry.

Unusual binding of ursodeoxycholic acid to ileal bile acid binding protein: role in activation of FXRα[S]

Jeffrey W. Smith, F. Filipp, Changming Fang, 2012, Journal of Lipid Research.

Correcting a Fundamental Flaw in the Paradigm for Antimicrobial Susceptibility Testing

Jeffrey W. Smith, J. Marth, D. M. Heithoff, 2017, EBioMedicine.

38 – Prophylaxis in the Surgical Patient

Jeffrey W. Smith, R. Nichols, 1989 .

The Type III Connecting Segment of Fibronectin Contains an Aspartic Acid Residue that Regulates the Rate of Binding to Integrin α4β1

Jeffrey W. Smith, I. Jongewaard, P. M. Tsai, 1996 .

Inhibition of endothelial cell proliferation and angiogenesis by orlistat, a fatty acid synthase inhibitor

Jeffrey W. Smith, C. D. Browne, E. Hindmarsh, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Suppression of the human mucosal-related colonic microflora with prophylactic parenteral and/or oral antibiotics

Jeffrey W. Smith, Mark B. Smith, V. Goradia, 1990, World Journal of Surgery.

Effects of commonly used bowel preparations on the large bowel mucosal-associated and luminal microflora in the rat model

Jeffrey W. Smith, R. Nichols, S. McClugage, 1990, Diseases of the colon and rectum.

Vascular Proteome Responses Precede Organ Dysfunction in a Murine Model of Staphylococcus aureus Bacteremia

James T. Sorrentino, Jeffrey W. Smith, V. Nizet, 2022, mSystems.

The Cell Adhesion Domain in Plasma Vitronectin Is Cryptic*

Jeffrey W. Smith, D. Seiffert, 1997, The Journal of Biological Chemistry.

Glutamine‐fueled mitochondrial metabolism is decoupled from glycolysis in melanoma

Boris Ratnikov, Jeffrey W. Smith, A. Osterman, 2012, Pigment cell & melanoma research.

Practical, catalytic, asymmetric synthesis of beta-lactones via a sequential ketene dimerization/hydrogenation process: inhibitors of the thioesterase domain of fatty acid synthase.

Jeffrey W. Smith, D. Romo, Robyn D. Richardson, 2006, The Journal of organic chemistry.

Beta-lactam congeners of orlistat as inhibitors of fatty acid synthase.

Jeffrey W. Smith, D. Romo, Wei Zhang, 2008, Bioorganic & medicinal chemistry letters.

Synthesis of novel beta-lactone inhibitors of fatty acid synthase.

Jeffrey W. Smith, P. Cieplak, D. Romo, 2008, Journal of medicinal chemistry.

Practical, Catalytic, Asymmetric Synthesis of β-Lactones via a Sequential Ketene Dimerization/Hydrogenation Process: Inhibitors of the Thioesterase Domain of Fatty Acid Synthase.

Jeffrey W. Smith, D. Romo, Robyn D. Richardson, 2006 .

Total synthesis and comparative analysis of orlistat, valilactone, and a transposed orlistat derivative: Inhibitors of fatty acid synthase.

Jeffrey W. Smith, D. Romo, Robyn D. Richardson, 2006, Organic Letters.

Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responses

Jeffrey W. Smith, E. Ruoslahti, E. Pasquale, 2000, Oncogene.

PMAP: databases for analyzing proteolytic events and pathways

Sarah Boyd, Jeffrey W. Smith, Michael L. Blinov, 2008, Nucleic Acids Res..

CutDB: a proteolytic event database

Jeffrey W. Smith, Adam Godzik, Andrei Osterman, 2006, Nucleic Acids Res..

Host-dependent Induction of Transient Antibiotic Resistance: A Prelude to Treatment Failure

Jeffrey W. Smith, J. Marth, D. M. Heithoff, 2015, EBioMedicine.

Multicenter, Randomized Study Comparing Levofloxacin and Ciprofloxacin for Uncomplicated Skin and Skin Structure Infections

Jeffrey W. Smith, L. Gentry, R. R. Williams, 1997, Southern medical journal.

Comparative Metabolic Flux Profiling of Melanoma Cell Lines

Andrei L Osterman, Fabian V Filipp, Jeffrey W. Smith, 2011, The Journal of Biological Chemistry.

The Methylation-Driven Logic of Alu Lineage

Jeffrey W. Smith, K. Gramatikoff, 2014 .

Crystal and solution structures of a prokaryotic M16B peptidase: an open and shut case.

Greg L. Hura, Jeffrey W. Smith, A. Strongin, 2009, Structure.

4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N‐Ras proto‐oncogenes in mice

Jeffrey W. Smith, D. Calvisi, Xin Chen, 2015, Hepatology.

Plasma Proteome Signature of Sepsis: a Functionally Connected Protein Network

Jeffrey W. Smith, J. Marth, J. Esko, 2019, Proteomics.

Orlistat Is a Novel Inhibitor of Fatty Acid Synthase with Antitumor Activity

Jeffrey W. Smith, S. Kridel, F. Axelrod, 2004, Cancer Research.

Proteins and an inflammatory network expressed in colon tumors.

Jeffrey W. Smith, Wenhong Zhu, K. Gramatikoff, 2011, Journal of proteome research.

A Fatty Acid Synthase Blockade Induces Tumor Cell-cycle Arrest by Down-regulating Skp2*

Jeffrey W. Smith, L. Knowles, C. D. Browne, 2004, Journal of Biological Chemistry.

Inhibition of Fatty-acid Synthase Induces Caspase-8-mediated Tumor Cell Apoptosis by Up-regulating DDIT4*

Jeffrey W. Smith, A. Osterman, L. Knowles, 2008, Journal of Biological Chemistry.

Profiling of central metabolism in human cancer cells by two-dimensional NMR, GC-MS analysis, and isotopomer modeling

Jeffrey W. Smith, A. Osterman, A. Richardson, 2008, Metabolomics.

Metabolic rewiring in melanoma

Jeffrey W. Smith, A. Osterman, Z. Ronai, 2016, Oncogene.

A Residue in the S2 Subsite Controls Substrate Selectivity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9*

Jeffrey W. Smith, A. Godzik, Weizhong Li, 2003, Journal of Biological Chemistry.

Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies.

Jeffrey W. Smith, G. Mills, Y. Kluger, 2015, Cancer cell.

Mass Spectrometry-Based Label-Free Quantitative Proteomics

Jeffrey W. Smith, Chun-Ming Huang, Wenhong Zhu, 2009, Journal of biomedicine & biotechnology.

Inactivation of Adenomatous Polyposis Coli Reduces Bile Acid/Farnesoid X Receptor Expression through Fxr gene CpG Methylation in Mouse Colon Tumors and Human Colon Cancer Cells.

Jeffrey W. Smith, T. Doetschman, P. Lance, 2016, The Journal of nutrition.

Pharmacogenomic and clinical data link non-pharmacokinetic metabolic dysregulation to drug side effect pathogenesis

Aarash Bordbar, Daniel C. Zielinski, Bernhard O Palsson, 2015, Nature Communications.

Switching the Substrate Specificity of the Two-Component NS2B-NS3 Flavivirus Proteinase by Structure-Based Mutagenesis

Jeffrey W. Smith, A. Strongin, R. Liddington, 2007, Journal of Virology.

Gene expression profiling of tumor xenografts: In vivo analysis of organ‐specific metastasis

Jeffrey W. Smith, Limin Liu, E. C. Lin, 2003, International journal of cancer.

Extracellular and intracellular mechanisms that mediate the metastatic activity of exogenous osteopontin

Jeffrey W. Smith, K. Do, W. Arap, 2009, Cancer.

A Unique Substrate Binding Mode Discriminates Membrane Type-1 Matrix Metalloproteinase from Other Matrix Metalloproteinases*

Jeffrey W. Smith, A. Godzik, S. Kridel, 2002, The Journal of Biological Chemistry.

Maspin alters the carcinoma proteome

Jeffrey W. Smith, J. Yates, L. Florens, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Divalent cations regulate the organization of integrins αvβ3 and αvβ5 on the cell surface

Jeffrey W. Smith, Z. Ruggeri, I. Stuiver, 1996 .

The Ligand Recognition Specificity of Integrins (*)

Jeffrey W. Smith, E. Plow, K. Suehiro, 1996, The Journal of Biological Chemistry.

Three-Dimensional Structures of Full-Length, Membrane-Embedded Human α(IIb)β(3) Integrin Complexes.

Jeffrey W. Smith, N. Volkmann, D. Hanein, 2016, Biophysical journal.

Proteolysis of the Membrane Type-1 Matrix Metalloproteinase Prodomain

Jeffrey W. Smith, A. Strongin, Ilian A Radichev, 2007, Journal of Biological Chemistry.

Meropenem Versus Imipenem/Cilastatin in the Treatment of Hospitalized Patients With Skin and Soft Tissue Infections

Jeffrey W. Smith, S. Wilson, R. Nichols, 1995, Southern medical journal.

TARGETING OF MACROPHAGE FOAM CELLS IN ATHEROSCLEROTIC PLAQUE USING OLIGONUCLEOTIDE-FUNCTIONALIZED NANOPARTICLES.

Jeffrey W. Smith, G. Sharma, W. Stallcup, 2010, Nano LIFE.

Coagulation factor protein abundance in the pre-septic state predicts coagulopathic activities that arise during late-stage murine sepsis

Jeffrey W. Smith, J. Marth, W. Yang, 2022, EBioMedicine.

One-step fabrication of polymeric Janus nanoparticles for drug delivery.

Gaurav Sharma, Jeffrey W. Smith, Hui Xie, 2012, Langmuir : the ACS journal of surfaces and colloids.

Competitive Interactions of Collagen and a Jararhagin-derived Disintegrin Peptide with the Integrin α2-I Domain*

Jeffrey W. Smith, A. Bobkov, L. J. Lambert, 2008, Journal of Biological Chemistry.

Selection and Structure of Ion-selective Ligands for Platelet Integrin αIIbβ3 * 210

Jeffrey W. Smith, N. Assa‐Munt, N. Preece, 2002, The Journal of Biological Chemistry.

Vascular proteome responses precede organ dysfunction in sepsis

James T. Sorrentino, Jeffrey W. Smith, V. Nizet, 2021, bioRxiv.

A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma.

Jeffrey W. Smith, Jarrod Dean, Changming Fang, 2007, Cancer research.

Identification of a Region in the Integrin β3 Subunit That Confers Ligand Binding Specificity*

Jeffrey W. Smith, C. Barbas, C. Barbas, 1997, The Journal of Biological Chemistry.

NG2 Proteoglycan Ablation Reduces Foam Cell Formation and Atherogenesis via Decreased Low-Density Lipoprotein Retention by Synthetic Smooth Muscle Cells

Jeffrey W. Smith, W. Stallcup, Yunchao Chang, 2016, Arteriosclerosis, thrombosis, and vascular biology.

Comparative Metabolomics of Breast Cancer

Chen Yang, Jeffrey W. Smith, Andrei Osterman, 2006, Pacific Symposium on Biocomputing.

Right on TARGET: glutamine metabolism in cancer

Jeffrey W. Smith, Z. Ronai, B. Ratnikov, 2015, Oncoscience.

Risk Modification of Colorectal Adenoma by CYP7A1 Polymorphisms and the Role of Bile Acid Metabolism in Carcinogenesis

Jeffrey W. Smith, D. Alberts, P. Lance, 2011, Cancer Prevention Research.

The Amino-terminal One-third of Defines the Ligand Recognition Specificity of Integrin (*)

Jeffrey W. Smith, J. Zablocki, J. Loftus, 1996, The Journal of Biological Chemistry.

Substrate Hydrolysis by Matrix Metalloproteinase-9*

J W Smith, Jeffrey W. Smith, S. Kridel, 2001, The Journal of Biological Chemistry.

Evidence That the Integrin β3 and β5 Subunits Contain a Metal Ion-dependent Adhesion Site-like Motif but Lack an I Domain*

Jeffrey W. Smith, B. Ratnikov, E. C. Lin, 1997, The Journal of Biological Chemistry.

An Alternative Processing of Integrin αv Subunit in Tumor Cells by Membrane Type-1 Matrix Metalloproteinase*

Alex Y Strongin, Jeffrey W. Smith, A. Strongin, 2002, The Journal of Biological Chemistry.

Comparative proteomic analysis of a cytosolic fraction from β3 integrin-deficient cells.

Jeffrey W. Smith, J. Bush, S. Teitelbaum, 2012, Cancer genomics & proteomics.

Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis

James T. Sorrentino, Jeffrey W. Smith, V. Nizet, 2019, Nature Communications.

A Unique Substrate Recognition Profile for Matrix Metalloproteinase-2*

Jeffrey W. Smith, A. Godzik, S. Kridel, 2002, The Journal of Biological Chemistry.

An Allosteric Ca2+ Binding Site on the β3-Integrins That Regulates the Dissociation Rate for RGD Ligands*

Jeffrey W. Smith, C. Barbas, D. Hu, 1996, The Journal of Biological Chemistry.

DEPLETION OF TUMOR-ASSOCIATED MACROPHAGES WITH CLODRONATE-LOADED PLGA NANOPARTICLES

Jeffrey W. Smith, E. Ruoslahti, Hui Xie, 2013 .

Targeting tumor associated macrophages using clodronate-loaded PLGA nanoparticles

Jeffrey W. Smith, E. Ruoslahti, P. Karmali, 2010 .

Integrin activation controls metastasis in human breast cancer.

J W Smith, Jeffrey W. Smith, A. Saven, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Correction for Fogal et al., “Mitochondrial p32 Protein Is a Critical Regulator of Tumor Metabolism via Maintenance of Oxidative Phosphorylation”

Jeffrey W. Smith, E. Ruoslahti, A. Richardson, 2017, Molecular and Cellular Biology.

The vitronectin receptor alpha v beta 3 binds fibronectin and acts in concert with alpha 5 beta 1 in promoting cellular attachment and spreading on fibronectin

Jeffrey W. Smith, D. Cheresh, I. Charo, 1990, The Journal of cell biology.

Genome-wide changes accompanying knockdown of fatty acid synthase in breast cancer

Jeffrey W. Smith, L. Knowles, 2007, BMC Genomics.

Identification of a novel integrin binding site in fibronectin. Differential utilization by beta 3 integrins.

Jeffrey W. Smith, E. Getzoff, K. Yamada, 1994, The Journal of biological chemistry.

1 Proteolysis of the membrane type-1 matrix metalloproteinase ( MT 1-MMP ) prodomain : implications for a two-step proteolytic processing and activation

Jeffrey W. Smith, A. Strongin, Ilian A Radichev, 2007 .

A mechanism for divalent cation regulation of beta 3-integrins.

Jeffrey W. Smith, J. Smith, R. Piotrowicz, 1994, The Journal of biological chemistry.

Antitumor Activity Orlistat Is a Novel Inhibitor of Fatty Acid Synthase with Updated

Jeffrey W. Smith, S. Kridel, F. Axelrod, 2004 .

A series of function blocking antibodies against the alpha v beta 3 integrin bind allosteric to the ligand binding site and induce ligand dissociation.

Jeffrey W. Smith, C. Carron, J. Smith, 1998, Cell adhesion and communication.

4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N‐Ras proto‐oncogenes in mice

Jeffrey W. Smith, D. Calvisi, Xin Chen, 2015, Hepatology.

Comparative Metabolic Flux Profiling of Melanoma Cell Lines

Jeffrey W. Smith, A. Osterman, A. Richardson, 2011, The Journal of Biological Chemistry.

HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus.

Michael C. Myers, Jeffrey W. Smith, A. Strongin, 2007, Assay and drug development technologies.

High throughput substrate phage display for protease profiling.

Jeffrey W. Smith, P. Cieplak, B. Ratnikov, 2009, Methods in molecular biology.

Synthesis of novel beta-lactone inhibitors of fatty acid synthase.

Jeffrey W. Smith, P. Cieplak, D. Romo, 2008, Journal of medicinal chemistry.

Practical, catalytic, asymmetric synthesis of beta-lactones via a sequential ketene dimerization/hydrogenation process: inhibitors of the thioesterase domain of fatty acid synthase.

Jeffrey W. Smith, D. Romo, Robyn D. Richardson, 2006, The Journal of organic chemistry.

A Mechanism for Divalent Cation Regulation of &-Integrins *

Jeffrey W. Smith, D. Mathis, Randolph S. Piotrowiczg, 2001 .

Genome-wide changes accompanying knockdown of fatty acid synthase in breast cancer

Jeffrey W. Smith, L. Knowles, 2007, BMC Genomics.

Novel antagonists of the thioesterase domain of human fatty acid synthase

Jeffrey W. Smith, Robyn D. Richardson, 2007, Molecular Cancer Therapeutics.

Cloning and expression of genes encoding Haemophilus somnus antigens

Jeffrey W. Smith, L. Corbeil, D. Guiney, 1988, Infection and immunity.