Jeffrey T. Kuethe

发表

Development of an Efficient Route to 2-Ethynylglycerol for the Synthesis of Islatravir

Shaoguang Zhang, Gregory Hughes, Brian M. Wyvratt, 2021 .

Development of a Sequential Tetrahydropyran and Tertiary Butyl Deprotection: High-Throughput Experimentation, Mechanistic Analysis, and DOE Optimization

Nobuyoshi Yasuda, David M. Tellers, Jeffrey T. Kuethe, 2009 .

Asymmetric bioreduction of α,β-unsaturated nitriles and ketones

Paul N. Devine, Jeffrey T. Kuethe, F. Fleitz, 2008 .

Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor

Jeffrey T. Kuethe, D. Johns, T. Tucker, 2023, Circulation.

Discovery of N-[Bis(4-methoxyphenyl)methyl]-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide (MK-8617), an Orally Active Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase 1-3 (HIF PHD1-3) for the Treatment of Anemia.

Jeffrey T. Kuethe, J. Demartino, E. Sherer, 2016, Journal of medicinal chemistry.

A Rapid, Large-Scale Synthesis of a Potent Cholecystokinin (CCK) 1R Receptor Agonist

Jeffrey T. Kuethe, G. Humphrey, M. Journet, 2008 .

Utilizing biocatalysis and a sulfolane-mediated reductive acetal opening to access nemtabrutinib from cyrene

Jeffrey T. Kuethe, Justin A. Newman, T. Itoh, 2023, Green Chemistry.

Rapid and efficient synthesis of 1H-indol-2-yl-1H-quinolin-2-ones.

Jeffrey T. Kuethe, I. Davies, J. Kuethe, 2003, Organic letters.

A Series of Novel, Highly Potent, and Orally Bioavailable Next-Generation Tricyclic Peptide PCSK9 Inhibitors.

Jeffrey T. Kuethe, D. Johns, P. Orth, 2021, Journal of medicinal chemistry.

A facile synthesis of 2,3-disubstituted furo[2,3-b]pyridines

Jeffrey T. Kuethe, G. Beutner, N. Yasuda, 2009 .

A rapid synthesis of 2-aryl-5-substituted-2,3-dihydrobenzofurans.

Jeffrey T. Kuethe, I. Davies, M. Journet, 2005, The Journal of organic chemistry.

Using the Pummerer cyclization-deprotonation-cycloaddition cascade of imidosulfoxides for alkaloid synthesis.

Jeffrey T. Kuethe, A. Padwa, J. Kuethe, 2000, The Journal of organic chemistry.

A novel domino reaction for the preparation of substituted non-racemic β-proline derivatives

Jeffrey T. Kuethe, Jinsong Hao, J. Cumming, 2016 .

Practical methodologies for the synthesis of indoles.

Jeffrey T. Kuethe, G. Humphrey, J. Kuethe, 2006, Chemical reviews.

A concise synthesis of 3,4-fused spiro[isobenzofuran-3-ones], spiro[furo[3,4-b]pyridin-5(7H)-ones], 3-aryl-, and alkylphthalides

Jeffrey T. Kuethe, K. Maloney, J. Kuethe, 2013 .

Suzuki–Miyaura Cross-Coupling of 2-Nitroarenediazonium Tetrafluoroborates: Synthesis of Unsymmetrical 2-Nitrobiphenyls and Highly Functionalized Carbazoles

Jeffrey T. Kuethe, J. Kuethe, K. Childers, 2008 .

Discovery of Benzimidazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys.

Michael E. Lassman, Jeffrey T. Kuethe, M. Struthers, 2015, ACS medicinal chemistry letters.

Synthesis of a Complex and Highly Potent PCSK9 Inhibitor.

Jimmy O. DaSilva, Jeffrey T. Kuethe, E. Regalado, 2023, Organic letters.

Magnetically driven agitation in a tube mixer affords clog-resistant fast mixing independent of linear velocity.

Jeffrey T. Kuethe, Jeffrey T Kuethe, S. Dolman, 2011, The Journal of organic chemistry.

Omarigliptin (MK-3102): a novel long-acting DPP-4 inhibitor for once-weekly treatment of type 2 diabetes.

Kathy Lyons, Ping Chen, Dennis Feng, 2014, Journal of medicinal chemistry.

Multikilogram-Scale Synthesis of a Chiral Cyclopropanol and an Investigation of the Safe Use of Lithium Acetylide–Ethylene Diamine Complex

Daniel J. Muzzio, Jeffrey T. Kuethe, F. Fleitz, 2012 .

Preparation of 2-arylindole-4-carboxylic amide derivatives

Jeffrey T. Kuethe, I. Davies, J. Kuethe, 2006 .