Christopher J. R. Loewen

发表

MAPS: machine-assisted phenotype scoring enables rapid functional assessment of genetic variants by high-content microscopy

Jesse T. Chao, Calvin D. Roskelley, Christopher J. R. Loewen, 2021, BMC Bioinform..

Phosphatidic Acid Is a pH Biosensor That Links Membrane Biogenesis to Metabolism

Barry P. Young, Jesse T. Chao, Christopher J. R. Loewen, 2010, Science.

A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP

Christopher J. R. Loewen, C. Loewen, T. Levine, 2003, The EMBO journal.

ER-shaping proteins facilitate lipid exchange between the ER and mitochondria in S. cerevisiae

Barry P. Young, Christopher J. R. Loewen, W. Prinz, 2012, Journal of Cell Science.

Sentinel interaction mapping – a generic approach for the functional analysis of human disease gene variants using yeast

Barry P. Young, Jesse T. Chao, Christopher J. R. Loewen, 2020, Disease Models & Mechanisms.

A Highly Conserved Binding Site in Vesicle-associated Membrane Protein-associated Protein (VAP) for the FFAT Motif of Lipid-binding Proteins*

Christopher J. R. Loewen, C. Loewen, T. Levine, 2005, Journal of Biological Chemistry.

Molecular Characterization of Peripherin-2 and Rom-1 Mutants Responsible for Digenic Retinitis Pigmentosa*

Christopher J. R. Loewen, R. Molday, O. L. Moritz, 2001, The Journal of Biological Chemistry.

The role of subunit assembly in peripherin-2 targeting to rod photoreceptor disk membranes and retinitis pigmentosa.

Christopher J. R. Loewen, R. Molday, O. L. Moritz, 2003, Molecular biology of the cell.

Disulfide-mediated Oligomerization of Peripherin/Rds and Rom-1 in Photoreceptor Disk Membranes

Christopher J. R. Loewen, R. Molday, C. Loewen, 2000, The Journal of Biological Chemistry.

Global reorganization of budding yeast chromosome conformation in different physiological conditions

Frank Alber, Harianto Tjong, Daniel Müllner, 2016, The Journal of cell biology.

Proteomic analysis reveals the direct recruitment of intrinsically disordered regions to stress granules in S. cerevisiae

Christopher J. R. Loewen, E. Levy, J. Gsponer, 2020, Journal of Cell Science.

Selective aggregation of the splicing factor Hsh155 suppresses splicing upon genotoxic stress

Christopher S. Hughes, Christopher J. R. Loewen, G. Morin, 2017, The Journal of cell biology.

Genotoxin-induced transcriptional repression regulates selective protein aggregation

Christopher S. Hughes, Christopher J. R. Loewen, G. Morin, 2017, bioRxiv.

Polarization of the Endoplasmic Reticulum by ER-Septin Tethering

Barry P. Young, Jesse T. Chao, Christopher J. R. Loewen, 2014, Cell.

An Assembly of Proteins and Lipid Domains Regulates Transport of Phosphatidylserine to Phosphatidylserine Decarboxylase 2 in Saccharomyces cerevisiae *

Jennifer L. Jones, Christopher J. R. Loewen, D. Voelker, 2013, The Journal of Biological Chemistry.

Balony: a software package for analysis of data generated by synthetic genetic array experiments

Barry P. Young, Christopher J. R. Loewen, Christopher J. R. Loewen, 2013, BMC Bioinformatics.

Inheritance of cortical ER in yeast is required for normal septin organization

Barry P. Young, Christopher J. R. Loewen, C. Loewen, 2007, The Journal of cell biology.

A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria

Barry P. Young, Jesse T. Chao, Christopher J. R. Loewen, 2014, PLoS biology.

Inter-organelle membrane contact sites: through a glass, darkly.

Christopher J. R. Loewen, C. Loewen, T. Levine, 2006, Current opinion in cell biology.

Phospholipid Metabolism Regulated by a Transcription Factor Sensing Phosphatidic Acid

Christopher J. R. Loewen, S. Henry, N. Ktistakis, 2004, Science.

Barriers to uniformity within the endoplasmic reticulum.

Jesse T. Chao, Christopher J. R. Loewen, C. Loewen, 2014, Current opinion in cell biology.

Cysteine residues of photoreceptor peripherin/rds: role in subunit assembly and autosomal dominant retinitis pigmentosa.

Christopher J. R. Loewen, R. Molday, A. Goldberg, 1998, Biochemistry.

Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction

Barry P. Young, Christopher J. R. Loewen, C. Rankin, 2019, Nature Communications.

Prefoldin Promotes Proteasomal Degradation of Cytosolic Proteins with Missense Mutations by Maintaining Substrate Solubility

Barry P. Young, Christopher J. R. Loewen, T. Mayor, 2016, PLoS genetics.

A Premalignant Cell-Based Model for Functionalization and Classification of PTEN Variants

Kenneth A. Matreyek, Jesse T. Chao, Christopher J. R. Loewen, 2020, Cancer Research.

Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1.

Sheena C. Li, Jesse T. Chao, Christopher J. R. Loewen, 2021, Cell chemical biology.

High density array screening to identify the genetic requirements for transition metal tolerance in Saccharomyces cerevisiae.

Barry P. Young, Christopher J. R. Loewen, R. MacGillivray, 2011, Metallomics : integrated biometal science.

Faculty Opinions recommendation of Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pH(c) in Saccharomyces cerevisiae.

Christopher J. R. Loewen, C. Loewen, 2016 .

Cholesterol Homeostasis: Not until the SCAP Lady INSIGs

Christopher J. R. Loewen, C. Loewen, T. Levine, 2002, Current Biology.