Melanie V. Leveridge

发表

Improving the efficiency and effectiveness of an industrial SARS-CoV-2 diagnostic facility

Andy Neely, J. G. Bartlett, Chris Abell, 2022, Scientific Reports.

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Christopher J. Schofield, Cesar Ramirez-Molina, Udo Oppermann, 2012, Nature.

Identification of orally bioavailable small-molecule inhibitors of hematopoietic prostaglandin D2 synthase using X-ray fragment based drug discovery

Paul N. Mortenson, Melanie V. Leveridge, S. Teague, 2014 .

Application of Atypical Acetyl-Lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains.

Melanie V. Leveridge, P. Grandi, A. Michon, 2020, Journal of medicinal chemistry.

Fluorescent-Based Assays and RapidFire Mass Spectrometry Lead Discovery for Microsomal Prostaglandin E Synthase Using a Combination of High-Throughput

Melanie V. Leveridge, Stuart M. Baddeley, Benjamin R Bellenie, 2012 .

The Evolution of MALDI-TOF Mass Spectrometry toward Ultra-High-Throughput Screening: 1536-Well Format and Beyond

Melanie V. Leveridge, Rainer Paape, Peter S Marshall, 2016, Journal of biomolecular screening.

Enabling Lead Discovery for Histone Lysine Demethylases by High-Throughput RapidFire Mass Spectrometry

Melanie V. Leveridge, Stuart M. Baddeley, C. Chung, 2012, Journal of biomolecular screening.

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.

Andrew J. Bannister, Melanie V. Leveridge, S. Robson, 2016, Journal of medicinal chemistry.

Characterisation of Antibodies Against the Active Conformation of Gαi1 Using the SRU‐BIND® Label‐Free Detection System

Melanie V. Leveridge, C. Chung, T. Wattam, 2011 .

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives.

David M. Wilson, Melanie V. Leveridge, G. Drewes, 2016, Journal of medicinal chemistry.

Configuration of a High-Content Imaging Platform for Hit Identification and Pharmacological Assessment of JMJD3 Demethylase Enzyme Inhibitors

Melanie Leveridge, Emma Jones, John Liddle, 2012, Journal of biomolecular screening.

An iteratively optimised process for improving the e ciency and effectiveness of an industrial SARS- CoV-2 diagnostic facility

Christopher A. Brown, Emma L. Koppe, Melanie V. Leveridge, 2021 .

Advances in high‐throughput mass spectrometry in drug discovery

Melanie V. Leveridge, R. Annan, F. Büttner, 2022, EMBO molecular medicine.

Integration of Lead Discovery Tactics and the Evolution of the Lead Discovery Toolbox

Melanie Leveridge, Chun-Wa Chung, Jeffrey W Gross, 2018, SLAS discovery : advancing life sciences R & D.

Demonstrating Enhanced Throughput of RapidFire Mass Spectrometry through Multiplexing Using the JmjD2d Demethylase as a Model System

Peter Francis, Andy West, Melanie Leveridge, 2014, Journal of biomolecular screening.

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.

Douglas W. Thomson, David M. Wilson, Melanie V. Leveridge, 2016, Journal of medicinal chemistry.

A high-throughput MALDI-TOF MS biochemical screen for small molecule inhibitors of the antigen aminopeptidase ERAP1

Melanie V. Leveridge, R. Annan, Julie M Quayle, 2022, SLAS Discovery.

A High-Throughput Screen to Identify LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease Using RapidFire Mass Spectrometry

Melanie V. Leveridge, A. Reith, A. Nadin, 2016, Journal of biomolecular screening.

The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors.

I. E. Smith, Paul N. Mortenson, D. J. Price, 2019, Bioorganic & medicinal chemistry.

Lead Discovery for Microsomal Prostaglandin E Synthase Using a Combination of High-Throughput Fluorescent-Based Assays and RapidFire Mass Spectrometry

Melanie V. Leveridge, Stuart M. Baddeley, Benjamin R Bellenie, 2012, Journal of biomolecular screening.