Jonathan P. Davis

发表

Non-Canonical Interaction between Calmodulin and Calcineurin Contributes to the Differential Regulation of Plant-Derived Calmodulins on Calcineurin

Peter M. Kekenes-Huskey, Christopher N. Johnson, Bin Sun, 2021, J. Chem. Inf. Model..

Gene Transfer of Engineered Calmodulin Alleviates Ventricular Arrhythmias in a Calsequestrin‐Associated Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia

Jonathan P. Davis, S. Priori, B. Liu, 2018, Journal of the American Heart Association.

Myofilament Calcium Sensitivity: Role in Regulation of In vivo Cardiac Contraction and Relaxation

Paul M. L. Janssen, Jonathan P. Davis, Jae-Hoon Chung, 2016, Front. Physiol..

Designing Calcium-sensitizing Mutations in the Regulatory Domain of Cardiac Troponin C*

Jonathan P. Davis, S. Tikunova, Svetlana B. Tikunova, 2004, Journal of Biological Chemistry.

Impact of heart rate on cross-bridge cycling kinetics in failing and non-failing human myocardium.

Peter J. Mohler, Bryan A. Whitson, Noah Weisleder, 2019, American journal of physiology. Heart and circulatory physiology.

Designing proteins to combat disease: Cardiac troponin C as an example.

Jalal K. Siddiqui, Jonathan P. Davis, B. Liu, 2016, Archives of biochemistry and biophysics.

Staurosporine Inhibits Frequency-Dependent Myofilament Desensitization in Intact Rabbit Cardiac Trabeculae

Jonathan P. Davis, P. Janssen, B. Biesiadecki, 2012, Biochemistry research international.

Calmodulin/Calcineurin Interaction Beyond the Calmodulin-binding Region Contributes to Calcineurin Activation.

Jonathan P. Davis, T. Creamer, Bin Sun, 2019, Biochemistry.

3-Chlorodiphenylamine activates cardiac troponin by a mechanism distinct from bepridil or TFP

Jonathan P. Davis, P. Hwang, S. Tikunova, 2018, The Journal of general physiology.

Successful Identification of Cardiac Troponin Calcium Sensitizers Using a Combination of Virtual Screening and ROC Analysis of Known Troponin C Binders

Jonathan P. Davis, S. Lindert, Melanie L. Aprahamian, 2017, J. Chem. Inf. Model..

IL-27 gene therapy induces depletion of Tregs and enhances the efficacy of cancer immunotherapy.

Jonathan P. Davis, X. Pan, A. Satoskar, 2018, JCI insight.

Identification of a Region of Troponin I Important in Signaling Cross-bridge-dependent Activation of Cardiac Myofilaments*

Jonathan P. Davis, R. Solaro, S. Tikunova, 2007, Journal of Biological Chemistry.

Redundant and diverse intranodal pacemakers and conduction pathways protect the human sinoatrial node from failure

Jonathan P. Davis, J. Hummel, R. Weiss, 2017, Science Translational Medicine.

Cardiac troponin T isoforms affect the Ca(2+) sensitivity of force development in the presence of slow skeletal troponin I: insights into the role of troponin T isoforms in the fetal heart.

Jonathan P. Davis, A. Gomes, J. Potter, 2004, The Journal of biological chemistry.

Understanding Ion Binding Affinity and Selectivity in β-Parvalbumin Using Molecular Dynamics and Mean Spherical Approximation Theory.

Caitlin E. Scott, Jonathan P. Davis, P. Kekenes-Huskey, 2016, The journal of physical chemistry. B.

are permissive of high Ca2+ affinity of site II Sequence mutations in teleost cardiac troponin C that

Jonathan P. Davis, M. Regnier, S. Tikunova, 2007 .

Myofibrillar determinants of rate of relaxation in skinned skeletal muscle fibers.

Jonathan P. Davis, L. Smillie, Ye Luo, 2003, Advances in experimental medicine and biology.

Determinants of relaxation rate in rabbit skinned skeletal muscle fibres

Jonathan P. Davis, L. Smillie, Ye Luo, 2002, The Journal of physiology.

Combined troponin I Ser-150 and Ser-23/24 phosphorylation sustains thin filament Ca(2+) sensitivity and accelerates deactivation in an acidic environment.

Jonathan P. Davis, B. Zhang, Shane D. Walton, 2014, Journal of molecular and cellular cardiology.

Obligatory role of neuronal nitric oxide synthase in the heart's antioxidant adaptation with exercise.

Jonathan P. Davis, S. Houser, S. Györke, 2015, Journal of molecular and cellular cardiology.

Engineered Troponin C Constructs Correct Disease-related Cardiac Myofilament Calcium Sensitivity*

Jonathan P. Davis, Ryan S. Lee, B. Liu, 2012, The Journal of Biological Chemistry.

Muscle Twitch Kinetics Are Dependent on Muscle Group, Disease State, and Age in Duchenne Muscular Dystrophy Mouse Models

Jonathan P. Davis, Jeovanna Lowe, J. Rafael-Fortney, 2020, Frontiers in Physiology.

Effects of Modified Parvalbumin EF-Hand Motifs on Cardiac Myocyte Contractile Function.

Jalal K. Siddiqui, Jonathan P. Davis, J. Metzger, 2016, Biophysical journal.

Engineering Parvalbumin for the Heart: Optimizing the Mg2+ Binding Properties of Rat β-Parvalbumin

Jonathan P. Davis, George Zhang, Vikram K. Shettigar, 2011, Front. Physio..

Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction

Jonathan P. Davis, C. Yengo, G. Lopaschuk, 2022, Frontiers in Physiology.

Engineering Competitive Magnesium Binding into the First EF-hand of Skeletal Troponin C*

Jonathan P. Davis, L. Smillie, S. Tikunova, 2002, The Journal of Biological Chemistry.

Insights into length-dependent regulation of cardiac cross-bridge cycling kinetics in human myocardium.

Jonathan P. Davis, V. Fedorov, P. Mohler, 2016, Archives of biochemistry and biophysics.

Cardiac troponin I tyrosine 26 phosphorylation decreases myofilament Ca2+ sensitivity and accelerates deactivation.

Jonathan P. Davis, P. D. de Tombe, Shane D. Walton, 2014, Journal of molecular and cellular cardiology.

Cardiac Catheterization in Mice to Measure the Pressure Volume Relationship: Investigating the Bowditch Effect.

Jonathan P. Davis, B. Zhang, M. Ziolo, 2015, Journal of visualized experiments : JoVE.

Myofilament Calcium Sensitivity: Mechanistic Insight into TnI Ser-23/24 and Ser-150 Phosphorylation Integration

Jalal K. Siddiqui, Jonathan P. Davis, P. Janssen, 2016, Front. Physiol..

Rationally engineered Troponin C modulates in vivo cardiac function and performance in health and disease

Jonathan P. Davis, Bo Zhang, V. Fedorov, 2016, Nature Communications.

Jalal K. Siddiqui, Jonathan P. Davis, B. Liu, 2012, PloS one.

AMP-activated Protein Kinase Phosphorylates Cardiac Troponin I at Ser-150 to Increase Myofilament Calcium Sensitivity and Blunt PKA-dependent Function*

Jonathan P. Davis, R. Solaro, Sean C. Little, 2012, The Journal of Biological Chemistry.

The Need for Speed: Mice, Men, and Myocardial Kinetic Reserve.

Jonathan P. Davis, P. Janssen, B. Biesiadecki, 2016, Circulation research.

Engineering an Anti-Arrhythmic Calmodulin

Jalal K. Siddiqui, Jonathan P. Davis, B. Liu, 2016 .

Effect of calcium-sensitizing mutations on calcium binding and exchange with troponin C in increasingly complex biochemical systems.

Jonathan P. Davis, A. Gomes, B. Liu, 2010, Biochemistry.

Measurement of Calcium Dissociation Rates from Troponin C in Rigor Skeletal Myofibrils

Jonathan P. Davis, S. Tikunova, Sean C. Little, 2011, Front. Physio..

Mutations of Hydrophobic Residues in the N-terminal Domain of Troponin C Affect Calcium Binding and Exchange with the Troponin C-Troponin I96–148 Complex and Muscle Force Production*

Jonathan P. Davis, S. Tikunova, J. Rall, 2004, Journal of Biological Chemistry.

In vitro analyses of suspected arrhythmogenic thin filament variants as a cause of sudden cardiac death in infants

Jonathan P. Davis, R. Morin, D. Tieleman, 2019, Proceedings of the National Academy of Sciences.

Sarcomere dynamics revealed by a myofilament integrated FRET-based biosensor in live skeletal muscle fibers

Jonathan P. Davis, J. Metzger, Dongwoo Hahn, 2022, Scientific Reports.

Ce-doped strontium cobalt ferrite perovskites as cathode catalysts for solid oxide fuel cells: Effect of dopant concentration

Jonathan P. Davis, U. Ozkan, Hyunkyung Choi, 2012 .

Systemic delivery of IL‐27 by an adeno‐associated viral vector inhibits T cell‐mediated colitis and induces multiple inhibitory pathways in T cells

Jonathan P. Davis, Jianmin Zhu, J. Yu, 2016, Journal of leukocyte biology.

Photorhabdus luminescens TccC3 Toxin Targets the Dynamic Population of F-Actin and Impairs Cell Cortex Integrity

Jonathan P. Davis, E. Egelman, Sarah M. Heissler, 2022, International journal of molecular sciences.

Protein Kinase C Phosphomimetics Alter Thin Filament Ca2+ Binding Properties

Jonathan P. Davis, B. Liu, B. Biesiadecki, 2014, PloS one.

Dissociation of Calcium Transients and Force Development following a Change in Stimulation Frequency in Isolated Rabbit Myocardium

K. M. Haizlip, Jonathan P. Davis, Shane D. Walton, 2015, BioMed research international.

Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation.

Jonathan P. Davis, C. Poggesi, B. Liu, 2013, Archives of biochemistry and biophysics.

Molecular basis of calmodulin-dependent calcineurin activation

Jonathan P. Davis, T. Creamer, Bin Sun, 2019, bioRxiv.

Peroxynitrite Increases Protein Phosphatase Activity and Promotes the Interaction of Phospholamban with Protein Phosphatase 2a in the Myocardium.

Jonathan P. Davis, Mark J. Kohr, M. Ziolo, 2009, Nitric oxide : biology and chemistry.

Familial hypertrophic cardiomyopathy-related cardiac troponin C mutation L29Q affects Ca2+ binding and myofilament contractility.

Jonathan P. Davis, S. Tikunova, G. Tibbits, 2008, Physiological genomics.

Activation of Smooth Muscle Myosin Light Chain Kinase by Calmodulin

David P. Wilson, Jonathan P. Davis, J. Johnson, 2002, The Journal of Biological Chemistry.

Effects of thin and thick filament proteins on calcium binding and exchange with cardiac troponin C.

Svetlana B Tikunova, Jonathan P Davis, Jonathan P. Davis, 2007, Biophysical journal.

Myofibrillar troponin exists in three states and there is signal transduction along skeletal myofibrillar thin filaments.

Svetlana B Tikunova, Jonathan P Davis, Jonathan P. Davis, 2006, Journal of molecular biology.

The Rates of Ca2+ Dissociation and Cross-bridge Detachment from Ventricular Myofibrils as Reported by a Fluorescent Cardiac Troponin C*

Jonathan P Davis, Ahmet Kilic, Jonathan P. Davis, 2012, The Journal of Biological Chemistry.

Protein phosphatase 2A regulatory subunit B56α limits phosphatase activity in the heart

Jonathan P. Davis, J. Curran, X. Wehrens, 2015, Science Signaling.

Ca++-sensitizing mutations in troponin, P(i), and 2-deoxyATP alter the depressive effect of acidosis on regulated thin-filament velocity.

Jonathan P. Davis, E. Debold, B. Biesiadecki, 2014, Journal of applied physiology.

NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model

Jonathan P. Davis, S. Liyanarachchi, D. Guttridge, 2018, Nature Communications.

Divergent Soybean Calmodulins Respond Similarly to Calcium Transients: Insight into Differential Target Regulation

Jalal K. Siddiqui, Jonathan P. Davis, Shane D. Walton, 2017, Front. Plant Sci..

Distributed synthesis of sarcolemmal and sarcoplasmic reticulum membrane proteins in cardiac myocytes

Jonathan P. Davis, S. Györke, S. Weinberg, 2021, Basic Research in Cardiology.

Interleukin-27 Gene Therapy Prevents the Development of Autoimmune Encephalomyelitis but Fails to Attenuate Established Inflammation due to the Expansion of CD11b+Gr-1+ Myeloid Cells

Jonathan P. Davis, Jianmin Zhu, Jin-qing Liu, 2018, Front. Immunol..

Interleukin‐27 signalling induces stem cell antigen‐1 expression in T lymphocytes in vivo

Jonathan P. Davis, A. Satoskar, Jianmin Zhu, 2017, Immunology.

In Utero Particulate Matter Exposure Produces Heart Failure, Electrical Remodeling, and Epigenetic Changes at Adulthood

Jonathan P. Davis, L. Wold, C. Carnes, 2017, Journal of the American Heart Association.

The non-canonical interaction between calmodulin and calcineurin contributes to the differential regulation of plant-derived calmodulins on calcineurin

Christopher N. Johnson, Jonathan P. Davis, Bin Sun, 2021, bioRxiv.

Regulation of Pulmonary Vascular Smooth Muscle Contractility in Pulmonary Arterial Hypertension: Implications for Therapy

Jonathan P. Davis, F. Brozovich, M. Lyle, 2017, Front. Physiol..

Ero1α-Dependent ERp44 Dissociation From RyR2 Contributes to Cardiac Arrhythmia

Tae Yun Kim, Jonathan P. Davis, Xun Ai, 2022, Circulation research.

Effect of Ce Doping on the Performance and Stability of Strontium Cobalt Ferrite Perovskites as SOFC Anode Catalysts

Jonathan P. Davis, U. Ozkan, Doruk Dogu, 2015, Topics in Catalysis.

Tri-modal regulation of cardiac muscle relaxation; intracellular calcium decline, thin filament deactivation, and cross-bridge cycling kinetics

Jonathan P. Davis, P. Janssen, B. Biesiadecki, 2014, Biophysical Reviews.

Influence of enhanced troponin C Ca2+‐binding affinity on cooperative thin filament activation in rabbit skeletal muscle

Jonathan P. Davis, M. Regnier, S. Tikunova, 2007, The Journal of physiology.

Noncanonical EF-hand motif strategically delays Ca2+ buffering to enhance cardiac performance

Jonathan P. Davis, J. Potter, J. Metzger, 2013, Nature Medicine.

Effect of muscle length on cross-bridge kinetics in intact cardiac trabeculae at body temperature

Jonathan P. Davis, K. Campbell, P. Janssen, 2013, The Journal of general physiology.

The Positive Inotropic Effect of Pyruvate Involves an Increase in Myofilament Calcium Sensitivity

Jonathan P. Davis, P. Janssen, Kenneth D. Varian, 2013, PloS one.

Discovery of Novel Small-Molecule Calcium Sensitizers for Cardiac Troponin C: A Combined Virtual and Experimental Screening Approach

Steffen Lindert, William H Coldren, Svetlana B Tikunova, 2020, J. Chem. Inf. Model..

Binding of calcium and magnesium to human cardiac troponin C

Jonathan P. Davis, S. Lindert, F. van Petegem, 2021, The Journal of biological chemistry.

Ca(2+) exchange with troponin C and cardiac muscle dynamics.

Svetlana B Tikunova, Jonathan P Davis, Jonathan P. Davis, 2008, Cardiovascular research.

Effect of hydrophobic residue substitutions with glutamine on Ca(2+) binding and exchange with the N-domain of troponin C.

Svetlana B Tikunova, Jonathan P Davis, Jonathan P. Davis, 2002, Biochemistry.

Myofilament Calcium Sensitivity: Consequences of the Effective Concentration of Troponin I

Jalal K. Siddiqui, Jonathan P. Davis, P. D. de Tombe, 2016, Front. Physiol..

Dissociation of force decline from calcium decline by preload in isolated rabbit myocardium

Jonathan P. Davis, P. Janssen, M. Monasky, 2008, Pflügers Archiv - European Journal of Physiology.

Modulation of the rate of cardiac muscle contraction by troponin C constructs with various calcium binding affinities.

Jonathan P. Davis, S. Tikunova, J. Rall, 2007, American journal of physiology. Heart and circulatory physiology.

NaV1.6 dysregulation within myocardial T-tubules by D96V calmodulin enhances proarrhythmic sodium and calcium mishandling

Jonathan P. Davis, D. Terentyev, Radmila Terentyeva, 2023, The Journal of clinical investigation.

The CaMKII inhibitor KN93-calmodulin interaction and implications for calmodulin tuning of NaV1.5 and RyR2 function.

Christopher N. Johnson, Jonathan P. Davis, R. Pattanayek, 2019, Cell calcium.

NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model

Jonathan P. Davis, S. Liyanarachchi, D. Guttridge, 2018, Nature Communications.

The Frank-Starling mechanism involves deceleration of cross-bridge kinetics and is preserved in failing human right ventricular myocardium.

Vadim V Fedorov, Jonathan P Davis, Ahmet Kilic, 2015, American journal of physiology. Heart and circulatory physiology.

In vivo assessment of contractile strength distinguishes differential gene function in skeletal muscle of zebrafish larvae.

Jonathan P. Davis, C. Beattie, S. Amacher, 2015, Journal of applied physiology.

Human disease-associated calmodulin mutations alter calcineurin function through multiple mechanisms.

Christopher N. Johnson, Jonathan P. Davis, Nicholas C. Fitzkee, 2023, Cell calcium.

Mouse Models of Cardiomyopathies Caused by Mutations in Troponin C

Jonathan P. Davis, S. Tikunova, Jenna Thuma, 2023, International journal of molecular sciences.

Targeting Troponin C with Small Molecules Containing Diphenyl Moieties: Calcium Sensitivity Effects on Striated Muscles and Structure-Activity Relationship

Jonathan P. Davis, S. Lindert, S. Tikunova, 2023, J. Chem. Inf. Model..

Effects of increased systolic Ca(2+) and β-adrenergic stimulation on Ca(2+) transient decline in NOS1 knockout cardiac myocytes.

Jonathan P. Davis, P. Janssen, B. Biesiadecki, 2012, Nitric oxide : biology and chemistry.

Effect of Ca2+ binding properties of troponin C on rate of skeletal muscle force redevelopment.

Jonathan P. Davis, Ryan S. Lee, N. Minh, 2010, American journal of physiology. Cell physiology.

skeletal muscle force redevelopment binding properties of troponin C on rate of 2+ Effect of Ca

Jonathan P. Davis, Ryan S. Lee, N. Minh, 2016 .

Tri-modal regulation of cardiac muscle relaxation; intracellular calcium decline, thin filament deactivation, and cross-bridge cycling kinetics

Jonathan P. Davis, P. Janssen, B. Biesiadecki, 2014, Biophysical Reviews.

IL-27 gene therapy induces depletion of Tregs and enhances the efficacy of cancer immunotherapy.

Jonathan P. Davis, X. Pan, A. Satoskar, 2018, JCI insight.

The Need for Speed: Mice, Men, and Myocardial Kinetic Reserve.

Jonathan P. Davis, P. Janssen, B. Biesiadecki, 2016, Circulation research.

STIM1 ablation impairs exercise-induced physiologic cardiac hypertrophy and dysregulates autophagy in mouse hearts.

Jonathan P. Davis, D. Terentyev, Radmila Terentyeva, 2023, Journal of applied physiology.

cAMP-independent activation of protein kinase A by the peroxynitrite generator SIN-1 elicits positive inotropic effects in cardiomyocytes.

Jonathan P. Davis, Mark J. Kohr, M. Ziolo, 2010, Journal of molecular and cellular cardiology.

Modifying Mg2+ binding and exchange with the N-terminal of calmodulin.

Jonathan P. Davis, J. Johnson, S. Tikunova, 2001, Biochemistry.