Peter D Smith

发表

Perspectives on the Designation of Oligonucleotide Starting Materials

Martin Mehlmann, William F Kiesman, Andrew K McPherson, 2021, Nucleic acid therapeutics.

Tetrahydroisoquinoline Phenols: Selective Estrogen Receptor Downregulator Antagonists with Oral Bioavailability in Rat.

Peter D Smith, A. Rabow, R. A. Norman, 2016, ACS medicinal chemistry letters.

Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor.

Peter Ballard, Simon J Brown, Nathaniel G. Martin, 2014, Journal of medicinal chemistry.

Enantioselective Synthesis of Atropisomeric Biaryls using Biaryl 2,5‐Diphenylphospholanes as Ligands for Palladium‐Catalysed Suzuki‐Miyaura Reactions

Peter D Smith, Rachel Munday, P. Norrby, 2020 .

Tuning Reactivity in Pd‐catalysed C( sp 3 )‐H Arylations via Directing Group Modifications and Solvent Selection

Peter D Smith, T. Sheppard, A. Aliev, 2020, Advanced Synthesis & Catalysis.

Orally active achiral N-hydroxyformamide inhibitors of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) for the treatment of osteoarthritis.

Peter D Smith, Chris Davies, S. Lamont, 2011, Bioorganic & medicinal chemistry letters.

Asymmetric routes to substituted piperidines

Peter D Smith, P. Bailey, Paula A. Millwood, 1998 .

Novel 4-anilinoquinazolines with C-6 carbon-linked side chains: synthesis and structure-activity relationship of a series of potent, orally active, EGF receptor tyrosine kinase inhibitors.

Peter D Smith, J. Kendrew, Rebecca P A Ellston, 2006, Bioorganic & medicinal chemistry letters.

Discovery of a Thiadiazole-Pyridazine Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models.

Mairi M. Littleson, Peter D Smith, Peng-Fei Wang, 2019, Journal of medicinal chemistry.

The use of the aza-Diels–Alder reaction in the synthesis of pinidine and other piperidine alkaloids

Peter D Smith, G. Rosair, P. Bailey, 2002 .

Catalytic direct amidations in tert-butyl acetate using B(OCH2CF3)3

Peter D Smith, H. Hailes, T. Sheppard, 2019, Organic & biomolecular chemistry.

Pyruvate Enolate Arylation and Alkylation: OBO Ester Protected Pyruvates as Useful Reagents in Organic Synthesis.

Peter D Smith, T. Donohoe, Christopher J. J. Hall, 2017, Organic letters.

OBO-Protected Pyruvates as Reagents for the Synthesis of Functionalized Heteroaromatic Compounds.

Peter D Smith, T. Donohoe, K. Christensen, 2018, Organic letters.

Structure- and reactivity-based development of covalent inhibitors of the activating and gatekeeper mutant forms of the epidermal growth factor receptor (EGFR).

Matthew Grist, M Raymond V Finlay, Richard A Ward, 2013, Journal of medicinal chemistry.