J. Witte

John S Witte, J. Witte, D. Thomas, 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Software for hierarchical modeling of epidemiologic data.

S Greenland, J S Witte, J. Witte, 1998, Epidemiology.

Polygenic Inheritance of Paclitaxel-Induced Sensory Peripheral Neuropathy Driven by Axon Outgrowth Gene Sets in CALGB 40101 (Alliance)

J. Mefford, J. Witte, E. Winer, 2014, The Pharmacogenomics Journal.

Mutational Landscape of Aggressive Prostate Tumors in African American Men.

J. Mefford, J. Witte, Niall J Cardin, 2016, Cancer research.

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

J. Witte, M. Obeidat, Y. Bossé, 2019, bioRxiv.

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium

Yu-Han H. Hsu, Sanjay R. Patel, J. Witte, 2017, PLoS genetics.

Variation in the Glucose Transporter gene SLC2A2 is associated with glycaemic response to metformin

Mark I. McCarthy, Alison A. Motsinger-Reif, John S. Witte, 2016, Nature Genetics.

Congenital diaphragmatic hernia and maternal dietary nutrient pathways and diet quality

J. Witte, G. Shaw, S. Rasmussen, 2020, Birth defects research.

Pan-Cancer Study Detects Novel Genetic Risk Variants and Shared Genetic Basis in Two Large Cohorts

J. Witte, E. Ziv, S. K. Van Den Eeden, 2019, bioRxiv.

Strategies for Imputing and Analyzing Rare Variants in Association Studies.

J. Witte, T. Hoffmann, 2015, Trends in genetics : TIG.

Imputation of the Rare HOXB13 G84E Mutation and Cancer Risk in a Large Population-Based Cohort

J. Witte, N. Risch, M. Kvale, 2015, PLoS genetics.

Impact of Meat Consumption, Preparation, and Mutagens on Aggressive Prostate Cancer

J. Witte, E. Klein, I. Cheng, 2011, PloS one.

A Common 5′‐UTR Variant in MATE2‐K Is Associated With Poor Response to Metformin

J. Mefford, J. Witte, P. Kwok, 2011, Clinical pharmacology and therapeutics.

Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts

J. Witte, E. Ziv, S. K. Van Den Eeden, 2020, Nature Communications.

Age-of-onset information helps identify 76 genetic variants associated with allergic disease

Manuel A. R. Ferreira, J. Witte, G. Abecasis, 2020, PLoS genetics.

Case‐control analyses: Geneopardy!

J. Witte, E. Jorgenson, Xin Liu, 2005, Genetic epidemiology.

Coverage and power in genomewide association studies.

John S Witte, Eric Jorgenson, J. Witte, 2006, American journal of human genetics.

Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673–2682

J. Witte, Y. Kamatani, M. Lee, 2022, Diabetes care.

A genome‐wide association study of obstructive heart defects among participants in the National Birth Defects Prevention Study

J. Witte, A. Olshan, G. Shaw, 2022, American journal of medical genetics. Part A.

Methodological Considerations in Estimation of Phenotype Heritability Using Genome-Wide SNP Data, Illustrated by an Analysis of the Heritability of Height in a Large Sample of African Ancestry Adults

Gary K. Chen, M. C. Leske, J. Witte, 2015, PloS one.

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24.

Dennis J. Hazelett, M. C. Leske, J. Witte, 2016, Journal of the National Cancer Institute.

Population Genetic Simulations of Complex Phenotypes with Implications for Rare Variant Association Tests

Ryan D. Hernandez, Lawrence H. Uricchio, J. Witte, 2015, Genetic epidemiology.

An efficient Bayesian meta-analysis approach for studying cross-phenotype genetic associations

J. Witte, S. Bhattacharya, Arunabha Majumdar, 2017, bioRxiv.

Disease outcome in inflammatory bowel disease: mortality, morbidity and therapeutic management of a 796-person inception cohort in the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD).

J. Witte, J. Lennard-jones, C. Limonard, 2000, Scandinavian journal of gastroenterology.

The health effects of swimming in ocean water contaminated by storm drain runoff.

J. Witte, R. Millikan, R. Haile, 1999 .

Association of CYP2C9*2 With Bosentan‐Induced Liver Injury

J. Mefford, J. Witte, S. Markova, 2013, Clinical pharmacology and therapeutics.

Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk

J. Witte, D. Hadley, E. Ziv, 2017, PLoS genetics.

Sequence variation in folate pathway genes and risks of human cleft lip with or without cleft palate

J. Witte, G. Shaw, J. Rine, 2016, American journal of medical genetics. Part A.

A two-step approach to testing overall effect of gene-environment interaction for multiple phenotypes

Kathryn S. Burch, J. Witte, S. Sankararaman, 2020, bioRxiv.

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

Henry W. Long, M. C. Leske, J. Witte, 2016, Nature Communications.

Relation of serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 to risk of prostate cancer (United States)

J. Witte, F. Schumacher, G. Casey, 2003, Cancer Causes & Control.

Agreement in alcohol consumption levels as measured by two different questionnaires.

J. Witte, R. Haile, 1996, Journal of studies on alcohol.

Inflammatory bowel disease induces inflammatory and pre-neoplastic changes in the prostate

J. Witte, S. Abdulkadir, R. Vatapalli, 2021, Prostate Cancer and Prostatic Diseases.

CYP3A activity in African American and European American men: Population differences and functional effect of the CYP3A4*1B 5′‐promoter region polymorphism

J. Witte, C. Stein, C. Wandel, 2000, Clinical pharmacology and therapeutics.

Relationship between body size and prostate cancer in a sibling based case-control study.

J. Witte, G. Casey, B. Rybicki, 2005, The Journal of urology.

Personalized Prostate Cancer Screening Based on a Single Midlife Prostate-specific Antigen Measurement.

J. Witte, R. E. Graff, L. Kachuri, 2019, European urology.

Development and pilot evaluation of a personalized decision support intervention for low risk prostate cancer patients

J. Witte, M. Cooperberg, P. Carroll, 2019, Cancer medicine.

Detecting Rare Mutations with Heterogeneous Effects Using a Family-Based Genetic Random Field Method

J. Witte, Ming D Li, Q. Lu, 2018, Genetics.

Likelihood‐based approach to estimating twin concordance for dichotomous traits

J. Witte, J. Carlin, J. Hopper, 1999, Genetic epidemiology.

Correction: Inflammatory bowel disease induces inflammatory and preneoplastic changes in the prostate

J. Witte, S. Abdulkadir, R. Vatapalli, 2021, Prostate cancer and prostatic diseases.

PLOS ONE Polymorphisms of an Innate Immune Gene, Toll-Like Receptor 4, and Aggressive Prostate Cancer Risk: A Systematic Review and Meta-analysis

J. Witte, S. Chanock, R. Eeles, 2014 .

Identification and fine mapping of a region showing a high frequency of allelic imbalance on chromosome 16q23.2 that corresponds to a prostate cancer susceptibility locus.

J. Witte, W. Catalona, H. Levin, 2000, Cancer research.

Global Patterns of Prostate Cancer Incidence, Aggressiveness, and Mortality in Men of African Descent

J. Witte, T. Rebbeck, R. Eeles, 2013, Prostate cancer.

Nonsteroidal antiinflammatory drugs and decreased risk of advanced prostate cancer: modification by lymphotoxin alpha.

J. Witte, G. Casey, N. Nock, 2006, American journal of epidemiology.

Performance of the Genomic Evaluators of Metastatic Prostate Cancer (GEMCaP) Tumor Biomarker for Identifying Recurrent Disease in African American Patients

J. Witte, A. Levin, B. Rybicki, 2014, Cancer Epidemiology, Biomarkers & Prevention.

Trans-fatty acid intake and increased risk of advanced prostate cancer: modification by RNASEL R462Q variant.

J. Witte, F. Schumacher, G. Casey, 2007, Carcinogenesis.

A case-control study of reproductive variables, alcohol, and smoking in premenopausal bilateral breast cancer

J. Witte, W. Thompson, J. Siemiatycki, 2005, Breast Cancer Research and Treatment.

Plasma carotenoids and the prevalence of adenomatous polyps of the distal colon and rectum.

C. L. Bird, J. Witte, J. Shikany, 1997, American journal of epidemiology.

No Association between Genetic Polymorphisms in Insulin and Insulin Receptor Substrate-1 and Prostate Cancer

J. Witte, G. Casey, M. Cicek, 2005, Cancer Epidemiology Biomarkers & Prevention.

Cancer systems epidemiology: Overcoming misconceptions and integrating systems approaches into cancer research

Bruce Y. Lee, J. Witte, P. Mabry, 2022, PLoS medicine.

Association Between a 22-feature Genomic Classifier and Biopsy Gleason Upgrade During Active Surveillance for Prostate Cancer

J. Witte, M. Cooperberg, W. Catalona, 2021, medRxiv.

Correction: Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry

Gary K. Chen, Sanjay R. Patel, J. Witte, 2011, PLoS Genetics.

Genetic Dissection of Complex Traits with Chromosome Substitution Strains of Mice

Eric S. Lander, John S. Witte, Joseph H. Nadeau, 2004, Science.

Determining Which Phenotypes Underlie a Pleiotropic Signal

J. Witte, Arunabha Majumdar, T. Haldar, 2016, Genetic epidemiology.

A genome‐wide association study of prostate cancer in Latinos

J. Witte, C. Haiman, S. Ingles, 2017, International journal of cancer.

Clinical trials in the genomic era: effects of protective genotypes on sample size and duration of trial.

J. Witte, J. M. Hall, B. Fijal, 2000, Controlled clinical trials.

MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance.

J. Witte, R. Bejar, S. Nahas, 2015, Blood.

Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer

Marshall W. Anderson, J. Witte, Y. Bossé, 2022, Nature Genetics.

Efficient estimation and applications of cross-validated genetic predictions

Danny S. Park, J. Mefford, J. Witte, 2019, bioRxiv.

Cell-free DNA concentration fragment size as a biomarker for prostate

J. Witte, A. Wyatt, Clinton L. Cario, 2021 .

Relation between tumour necrosis factor polymorphism TNFα-308 and risk of asthma

J. Witte, L. Palmer, P. Hopkins, 2002, European Journal of Human Genetics.

Genetic Analysis of Lung Cancer and the Germline Impact on Somatic Mutation Burden

Aurélie A G Gabriel, J. Witte, P. Brennan, 2022, Journal of the National Cancer Institute.

Residential particulate matter, proximity to major roads, traffic density and traffic volume as risk factors for preterm birth in California.

J. Witte, R. Baer, L. Jelliffe‐Pawlowski, 2021, Paediatric and perinatal epidemiology.

Diacylglycerol kinase K variants impact hypospadias in a California study population.

J. Witte, S. Choudhry, G. Shaw, 2013, The Journal of urology.

Comparison of missing data approaches in linkage analysis

J. Witte, D. Conti, F. Schumacher, 2003, BMC Genetics.

Leveraging Genetic Determinants of Prostate-Specific Antigen Levels Towards Improving Prostate Cancer Screening

J. Witte, S. Chanock, C. Haiman, 2022 .

Impact of Preadjusting a Quantitative Phenotype Prior to Sib‐Pair Linkage Analysis when Gene×Environment Interaction Exists

J. Witte, R. Elston, D. Conti, 2001, Genetic epidemiology.

Genetic polymorphisms in ESR1 and ESR2 genes, and risk of hypospadias in a multiethnic study population.

J. Witte, S. Choudhry, G. Shaw, 2015, The Journal of urology.

Using hierarchical modeling in genetic association studies with multiple markers: application to a case-control study of bladder cancer.

John S Witte, Stefano Porru, Paolo Boffetta, 2004, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Nutrient Pathways and Neural Tube Defects: A Semi-Bayesian Hierarchical Analysis

J. Witte, G. Shaw, S. Carmichael, 2009, Epidemiology.

Familial prostate cancer: a different disease?

J. Witte, E. Klein, P. Kupelian, 1997, The Journal of urology.

Re: Biological aggressiveness of hereditary prostate cancer: long-term evaluation following radical prostatectomy.

J. Witte, E. Klein, P. Kupelian, 1999, The Journal of urology.

Family history of prostate cancer in patients with localized prostate cancer: an independent predictor of treatment outcome.

J. Witte, E. Klein, R. Macklis, 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Joint effects of genetic variants and residential proximity to pesticide applications on hypospadias risk.

J. Witte, G. Shaw, P. English, 2016, Birth defects research. Part A, Clinical and molecular teratology.

The contribution of genetic variants to disease depends on the ruler

J. Witte, P. Visscher, N. Wray, 2014, Nature Reviews Genetics.

Developments in our understanding of the genetic basis of birth defects.

Daniel M. Webber, J. Witte, G. Shaw, 2015, Birth defects research. Part A, Clinical and molecular teratology.

Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas.

J. Witte, N. Probst-Hensch, S. Ingles, 1998, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Dissecting Effects of Complex Mixtures: Who’s Afraid of Informative Priors?

Sander Greenland, Duncan C Thomas, John S Witte, 2007, Epidemiology.

Familial Risk and Heritability of Colorectal Cancer in the Nordic Twin Study of Cancer

J. Witte, K. Czene, H. Adami, 2017, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Dietary Omega-3 Fatty Acids, Cyclooxygenase-2 Genetic Variation, and Aggressive Prostate Cancer Risk

J. Witte, G. Casey, I. Cheng, 2009, Clinical Cancer Research.

Co-regulatory expression quantitative trait loci mapping: method and application to endometrial cancer

John S Witte, J. Witte, Kenneth S Kompass, 2011, BMC Medical Genomics.

COX2 genetic variation, NSAIDs, and advanced prostate cancer risk

J. Witte, G. Casey, X. Liu, 2007, British Journal of Cancer.

Association of the Innate Immunity and Inflammation Pathway with Advanced Prostate Cancer Risk

J. Mefford, J. Witte, A. Levin, 2012, PloS one.

Variants in Deleted in AZoospermia-Like (DAZL) are correlated with reproductive parameters in men and women

J. Witte, J. Tung, D. Cramer, 2006, Human Genetics.

A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility

J. Mefford, J. Witte, N. Risch, 2020, Cancer Research.

Identification of Pleiotropic Cancer Susceptibility Variants from Genome-Wide Association Studies Reveals Functional Characteristics

J. Witte, E. Ziv, T. Hoffmann, 2017, Cancer Epidemiology, Biomarkers & Prevention.

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Laura J. Scott, Naomi R. Wray, Margaret A. Pericak-Vance, 2015, Nature Neuroscience.

Identifying Causal Genetic Factors

J. Witte, C. Amos, W. Newman, 2006 .

Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants

John S. Witte, Chun Jimmie Ye, Ryan D. Hernandez, 2016, Genome research.

A Genetic Signature of Spina Bifida Risk from Pathway-Informed Comprehensive Gene-Variant Analysis

J. Witte, G. Shaw, L. Pennacchio, 2011, PloS one.

Identification of novel susceptibility loci and genes for prostate cancer risk: A transcriptome-wide association study in over 140,000 European descendants.

Bogdan Pasaniuc, Xingyi Guo, John S Witte, 2019, Cancer research.

Genetic epidemiology and nonsyndromic structural birth defects: from candidate genes to epigenetics.

J. Witte, G. Shaw, B. Tycko, 2014, JAMA pediatrics.

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions.

Henry W. Long, Dennis J. Hazelett, M. C. Leske, 2015, Human molecular genetics.

Inclusion of variants discovered from diverse populations improves polygenic risk score transferability

J. Witte, Taylor B. Cavazos, 2020, bioRxiv.

Association Study of Over 200,000 Subjects Detects Novel Rare Variants, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility

J. Mefford, J. Witte, N. Risch, 2020, bioRxiv.

Tissue Sources for Accurate Measurement of Germline DNA Genotypes in Prostate Cancer Patients Treated With Radical Prostatectomy

J. Witte, M. Cooperberg, E. Wan, 2017, The Prostate.

Genome-Wide Meta-Analysis Validates a Roless for S1PR1 in Microtubule Targeting Agent-Induced Sensory Peripheral Neuropathy.

Katherina C. Chua, J. Witte, K. Owzar, 2020, Clinical pharmacology and therapeutics.

Hypospadias and genes related to genital tubercle and early urethral development.

John S Witte, Gary M Shaw, J. Witte, 2013, The Journal of urology.

Copy number alterations in prostate tumors and disease aggressiveness

Gary K. Chen, J. Witte, A. Levin, 2012, Genes, chromosomes & cancer.

Mapping methylation quantitative trait loci in cardiac tissues nominates risk loci and biological pathways in congenital heart disease

J. Witte, B. Tycko, Nianjun Liu, 2021, BMC genomic data.

The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury.

J. Witte, E. Ziv, E. Vittinghoff, 2012, Chest.

RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases

J. Witte, J. Carpten, J. Trent, 2002, Nature Genetics.

Inherited Susceptibility of Aggressive Prostate Cancer

J. Witte, A. Schnell, 2010 .

Prostate cancer genomics: towards a new understanding

John S. Witte, J. Witte, 2009, Nature Reviews Genetics.

Multiple prostate cancer risk variants on 8q24

J. Witte, 2007, Nature Genetics.

Carboxypeptidase 4 gene variants and early-onset intermediate-to-high risk prostate cancer

J. Witte, P. Carroll, G. Casey, 2009, BMC Cancer.

Two HLA Class II Gene Variants Are Independently Associated with Pediatric Osteosarcoma Risk

J. Witte, H. Hansen, J. Wiemels, 2018, Cancer Epidemiology, Biomarkers & Prevention.

An efficient Bayesian meta-analysis approach for studying cross-phenotype genetic associations

John S. Witte, Arunabha Majumdar, Tanushree Haldar, 2017, bioRxiv.

Cell-Free DNA Detection of Tumor Mutations in Heterogeneous, Localized Prostate Cancer Via Targeted, Multiregion Sequencing

Daniel K. Wells, J. Witte, P. Carroll, 2021, JCO precision oncology.

ω–3 Fatty Acids, Genetic Variants in COX-2 and Prostate Cancer

J. Witte, V. Fradet, A. Reese, 2009, Lifestyle Genomics.

Telomere structure and maintenance gene variants and risk of five cancer types

J. Witte, C. Ulrich, T. Sellers, 2016, International journal of cancer.

A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences.

Pui-Yan Kwok, Daniel J Schaid, John S Witte, 2015, Cancer discovery.

Genome-wide meta-analyses of smoking behaviors in African Americans

Gary K. Chen, J. Witte, M. Fornage, 2012, Translational Psychiatry.

Acute lung injury and the coagulation pathway: potential role of gene polymorphisms in the protein C and fibrinolytic pathways

J. Witte, M. Matthay, J. Wiemels, 2006, Intensive Care Medicine.

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

K. D. Sørensen, Ali Amin Al Olama, Lilit C Moss, 2021, Nature Genetics.

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

K. D. Sørensen, Ali Amin Al Olama, Lilit C Moss, 2021, Nature genetics.

Hereditary Prostate Cancer and Genetic Risk

J. Witte, G. Casey, A. Reese, 2012 .

DNA Repair Gene XRCC1 and XPD Polymorphisms and Risk of Prostate Cancer

J. Witte, D. Conti, G. Casey, 2004, Cancer Epidemiology Biomarkers & Prevention.

DNA Repair Gene XRCC1 and XPD Polymorphisms and Risk of Prostate Cancer

J. Witte, D. Conti, G. Casey, 2004, Cancer Epidemiology Biomarkers & Prevention.

Prostate cancer aggressiveness locus on chromosome segment 19q12–q13.1 identified by linkage and allelic imbalance studies

J. Witte, D. Conti, W. Catalona, 2003, Genes, chromosomes & cancer.

Prostate cancer aggressiveness locus on chromosome 7q32-q33 identified by linkage and allelic imbalance studies.

J. Witte, D. Conti, W. Catalona, 2002, Neoplasia.

Genomewide scan for prostate cancer-aggressiveness loci.

D V Conti, R C Elston, J S Witte, 2000, American journal of human genetics.

Next generation analytic tools for large scale genetic epidemiology studies of complex diseases

Kathryn Roeder, Peter Kraft, Matthew Stephens, 2012, Genetic epidemiology.

Comprehensive Approach to Analyzing Rare Genetic Variants

John S. Witte, Thomas J. Hoffmann, J. Witte, 2010, PloS one.

The landscape of host genetic factors involved in immune response to common viral infections

J. Witte, Y. Bossé, E. Ziv, 2020, Genome medicine.

The landscape of host genetic factors involved in immune response to common viral infections

J. Witte, Y. Bossé, E. Ziv, 2020, Genome Medicine.

Analysis of mutational spectra: locating hotspots and clusters of mutations using recursive segmentation

J. Witte, R. M. Idury, B. Fijal, 2002, Statistics in medicine.

Comment: A Human Genetics Perspective

Joel A. Mefford, Noah Zaitlen, John S. Witte, 2016 .

Inclusion of variants discovered from diverse populations improves polygenic risk score transferability.

J. Witte, Taylor B. Cavazos, 2020, HGG advances.

Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer

Pui-Yan Kwok, Olle Melander, Tobias Nordström, 2017, Nature Communications.

Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls

Gary K. Chen, J. Witte, S. Bull, 2013, Human Genetics.

Genome‐wide scan of brothers: Replication and fine mapping of prostate cancer susceptibility and aggressiveness loci

J. Witte, W. Catalona, B. Suarez, 2003, The Prostate.

Role of Androgen Metabolism Genes CYP1B1, PSA/KLK3, and CYP11α in Prostate Cancer Risk and Aggressiveness

J. Witte, G. Casey, M. Cicek, 2005, Cancer Epidemiology Biomarkers & Prevention.

Plasma Antioxidants, Genetic Variation in SOD2, CAT, GPX1, GPX4, and Prostate Cancer Survival

Stacey A. Kenfield, J. Witte, M. Stampfer, 2014, Cancer Epidemiology, Biomarkers & Prevention.

Cell-free DNA concentration and fragment size as a biomarker for prostate cancer

J. Witte, P. Carroll, A. Wyatt, 2021, Scientific reports.

Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts

J. Witte, E. Ziv, S. K. Van Den Eeden, 2020, Nature Communications.

Characterizing Genetic Risk at Known Prostate Cancer Susceptibility Loci in African Americans

Gary K. Chen, J. Witte, M. Thun, 2011, PLoS genetics.

Toll-Like Receptor 4 Genetic Variation and Advanced Prostate Cancer Risk

J. Witte, G. Casey, I. Cheng, 2007, Cancer Epidemiology Biomarkers & Prevention.

Polymorphisms in estrogen bioactivation, detoxification and oxidative DNA base excision repair genes and prostate cancer risk.

J. Witte, G. Casey, N. Nock, 2006, Carcinogenesis.

Validation of Genome-Wide Prostate Cancer Associations in Men of African Descent

J. Witte, S. Chanock, T. Rebbeck, 2010, Cancer Epidemiology, Biomarkers & Prevention.

Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms

J. Witte, E. Ziv, F. Feng, 2019, Nature Communications.

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

J. Witte, M. Obeidat, Y. Bossé, 2019, Nature Communications.

Turning of COGS moves forward findings for hormonally mediated cancers

John S Witte, Eric Jorgenson, J. Witte, 2013, Nature Genetics.

Genetic factors associated with prostate cancer conversion from active surveillance to treatment

J. Witte, M. Cooperberg, P. Carroll, 2021, medRxiv.

Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction

J. Witte, E. Ziv, M. Johansson, 2020, Nature Communications.

HOXB13 Mutation and Prostate Cancer: Studies of Siblings and Aggressive Disease

J. Mefford, J. Witte, G. Casey, 2013, Cancer Epidemiology, Biomarkers & Prevention.

Replication and Heritability of Prostate Cancer Risk Variants: Impact of Population-Specific Factors

J. Witte, T. Hoffmann, R. E. Graff, 2015, Cancer Epidemiology, Biomarkers & Prevention.

Generalizability of established prostate cancer risk variants in men of African ancestry

M. C. Leske, J. Witte, J. Carpten, 2015, International journal of cancer.

CYP3A4 and CYP3A5 genotypes, haplotypes, and risk of prostate cancer.

J. Witte, D. Conti, G. Casey, 2003, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

CYP 3 A 4 and CYP 3 A 5 Genotypes , Haplotypes , and Risk of Prostate Cancer 1

J. Witte, D. Conti, G. Casey, 2003 .

Polymorphisms of an Innate Immune Gene, Toll-Like Receptor 4, and Aggressive Prostate Cancer Risk: A Systematic Review and Meta-Analysis

J. Witte, S. Chanock, R. Eeles, 2014, PloS one.

Quantitative Spatial Profiling of PD-1/PD-L1 Interaction and HLA-DR/IDO-1 Predicts Improved Outcomes of Anti–PD-1 Therapies in Metastatic Melanoma

J. Witte, T. Ho, J. Kim, 2018, Clinical Cancer Research.

Mechanistic Phenotypes: An Aggregative Phenotyping Strategy to Identify Disease Mechanisms Using GWAS Data

Gerard Tromp, Yan Guo, Marylyn D. Ritchie, 2013, PloS one.

Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia

J. Mefford, J. Witte, K. Matsuda, 2013, Journal of Human Genetics.

Association of prostate cancer risk and aggressiveness to androgen pathway genes: SRD5A2, CYP17, and the AR

David V Conti, John S Witte, Graham Casey, 2004, The Prostate.

Comprehensive evaluation of the association between prostate cancer and genotypes/haplotypes in CYP17A1, CYP3A4, and SRD5A2

J. Witte, D. Rank, D. Conti, 2004, European Journal of Human Genetics.

Association between a CYP3A4 genetic variant and clinical presentation in African-American prostate cancer patients.

J. Witte, H. Levin, G. Casey, 1999, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Relationship between methylenetetrahydrofolate reductase C677T and A1298C genotypes and haplotypes and prostate cancer risk and aggressiveness.

J. Witte, D. Conti, G. Casey, 2004, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Newborn Metabolic Profile Associated with Hyperbilirubinemia With and Without Kernicterus

J. Witte, E. Rogers, K. Ryckman, 2018, Clinical and Translational Science.

Division of Allergy, Pulmonary & Critical Care Medicine Newsletter

J. Witte, E. Jorgenson, H. Hansen, 2016 .

Leveraging sequences missing from the human genome to diagnose cancer

J. Witte, M. Hemberg, N. Ahituv, 2021, medRxiv.

Assessment of genetic susceptibility to multiple primary cancers through whole-exome sequencing in two large multi-ancestry studies

J. Witte, E. Ziv, S. K. Van Den Eeden, 2022, BMC Medicine.

Segmentation and Estimation for SNP Microarrays: A Bayesian Multiple Change‐Point Approach

John S Witte, Yu Chuan Tai, Mark N Kvale, 2010, Biometrics.

Genetic Simulation Tools for Post‐Genome Wide Association Studies of Complex Diseases

Bo Peng, Vineet Bafna, Chun Li, 2015, Genetic epidemiology.

Model-free linkage analysis with covariates confirms linkage of prostate cancer to chromosomes 1 and 4.

J. Witte, K. Goddard, W. Catalona, 2001, American journal of human genetics.

Podocalyxin variants and risk of prostate cancer and tumor aggressiveness.

J. Witte, W. Catalona, G. Casey, 2006, Human molecular genetics.

Methods for Association Studies

J. Witte, R. E. Graff, L. Kachuri, 2021 .

The landscape of recombination in African Americans

Xiaofeng Zhu, Alex P. Reiner, Jasmin Divers, 2011, Nature.

Factors Associated with Time to Conversion from Active Surveillance to Treatment for Prostate Cancer in a Multi-Institutional Cohort

J. Witte, J. Eastham, D. Scholtens, 2021, The Journal of urology.

Multilevel Modeling in Epidemiology with GLIMMIX

S Greenland, J S Witte, J. Witte, 2000, Epidemiology.

COX-2 genetic variation, NSAIDs, and advanced prostate cancer risk.

J. Witte, G. Casey, I. Cheng, 2006 .

Hierarchical Regression Analysis Applied to a Study of Multiple Dietary Exposures and Breast Cancer

S Greenland, J S Witte, C L Bird, 1994, Epidemiology.

A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci

J. Witte, M. Lieber, G. Colditz, 2016, Cancer Epidemiology, Biomarkers & Prevention.

Selection and explosive growth may hamper the performance of rare variant association tests

Ryan D. Hernandez, Lawrence H. Uricchio, J. Witte, 2015, bioRxiv.

Does Accounting for Gene-Environment Interactions Help Uncover Association between Rare Variants and Complex Diseases?

John S. Witte, Rémi Kazma, J. Witte, 2013, Human Heredity.

Joint Association Testing of Common and Rare Genetic Variants Using Hierarchical Modeling

J. Mefford, J. Witte, Niall Cardin, 2012, Genetic epidemiology.

Use of principal components to aggregate rare variants in case-control and family-based association studies in the presence of multiple covariates

J. Witte, T. Hoffmann, R. Kazma, 2011, BMC proceedings.

Comparison of missing data approaches in linkage analysis

J. Witte, D. Conti, F. Schumacher, 2003, BMC Genetics.

Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry.

Jacob M. Keaton, Jack A. Taylor, J. Witte, 2023, European urology.

Relation of vegetable, fruit, and grain consumption to colorectal adenomatous polyps.

C. L. Bird, J. Witte, M. Longnecker, 1996, American journal of epidemiology.

A sigmoidoscopy‐based case–control study of polyps: macronutrients, fiber and meat consumption

J. Witte, M. Longnecker, N. Probst-Hensch, 1997, International journal of cancer.

Association Between Alzheimer Disease and Cancer With Evaluation of Study Biases

J. Witte, R. E. Graff, L. Kobayashi, 2020, JAMA network open.

The competing risk of death and selective survival cannot fully explain the inverse cancer‐dementia association

J. Witte, M. Glymour, R. E. Graff, 2020, Alzheimer's & Dementia.

Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases.

Bhramar Mukherjee, Peng Wei, Kimberly McAllister, 2017, American journal of epidemiology.

A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry.

J. Witte, G. Colditz, A. Olshan, 2020, Blood advances.

Genome-wide association studies and beyond.

J. Witte, 2010, Annual review of public health.

Personalized Prostate Cancer Screening: Improving PSA Tests with Genomic Information

J. Witte, 2010, Science Translational Medicine.

Cell-free DNA as a biomarker for prostate cancer: elevated concentration and decreased fragment size

J. Witte, P. Carroll, A. Wyatt, 2020, bioRxiv.

Update on the State of the Science for Analytical Methods for Gene-Environment Interactions.

Seunggeun Lee, Bhramar Mukherjee, Nilanjan Chatterjee, 2017, American journal of epidemiology.

Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases

James L. Mohler, Elaine A. Ostrander, Timothy R. Rebbeck, 2015, Human Genetics.

No association between a tetranucleotide repeat polymorphism of CYP19 and prostate cancer.

J. Witte, G. Casey, M. Cicek, 2004, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

No association between genetic polymorphisms in IGF-I and IGFBP-3 and prostate cancer.

J. Witte, G. Casey, M. Cicek, 2004, Cancer Epidemiology, Biomarkers and Prevention.

Genome-wide scan of 29,141 African Americans finds no evidence of selection since admixture

J. Witte, D. Reich, R. Millikan, 2013, 1312.2675.

Genetic Determinants of Blood Cell Traits Influence Susceptibility to Childhood Acute Lymphoblastic Leukemia

J. Witte, C. Chiang, Xiaomei Ma, 2021, medRxiv.

Socioeconomic status and prostate cancer incidence and mortality rates among the diverse population of California

J. Witte, E. John, C. Clarke, 2009, Cancer Causes & Control.

Vitamin D Receptor Genotypes/Haplotypes and Prostate Cancer Risk

J. Witte, F. Schumacher, G. Casey, 2006, Cancer Epidemiology Biomarkers & Prevention.

Plasminogen activator inhibitor type‐1 (PAI‐1) polymorphism 4G/5G is associated with prostate cancer among men with a positive family history

John S Witte, Graham Casey, Sarah Plummer, 2007, The Prostate.

Detecting gene-environment interactions in human birth defects: Study designs and statistical methods.

John S Witte, Jinghua Liu, Gary M Shaw, 2015, Birth defects research. Part A, Clinical and molecular teratology.

Enriching the analysis of genomewide association studies with hierarchical modeling.

Gary K. Chen, John S Witte, Gary K Chen, 2007, American journal of human genetics.

8q24 and prostate cancer: association with advanced disease and meta-analysis

J. Witte, G. Casey, E. Jorgenson, 2008, European Journal of Human Genetics.

Prostatitis, Sexually Transmitted Diseases, and Prostate Cancer: The California Men's Health Study

J. Witte, S. K. Van Den Eeden, C. Quesenberry, 2007, PloS one.

Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans

J. Mefford, J. Witte, Jeffrey N. Martin, 2016, AIDS.

The role of genetic variation in Toll-like receptor 4 in prostate cancer susceptibility: a review.

J. Witte, I. Cheng, 2008, Expert opinion on medical diagnostics.

Parametric linkage analysis.

J. Witte, R. Elston, L. Palmer, 2002, Methods in molecular biology.

Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.

Scott M. Williams, Yu-Han H. Hsu, Nicholette D. Palmer, 2021, American journal of human genetics.

MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance.

J. Witte, R. Bejar, C. Hader, 2015, Blood.

Testing drug response in the presence of genetic information: sampling issues for clinical trials.

R C Elston, J S Witte, R M Idury, 2000, Pharmacogenetics.

Replication linkage study for prostate cancer susceptibility genes

J. Witte, M. Resnick, D. Conti, 2000, The Prostate.

Red cell and plasma folate, folate consumption, and the risk of colorectal adenomatous polyps.

C. L. Bird, J. Witte, M. Longnecker, 1995, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Selenoprotein and antioxidant genes and the risk of high‐grade prostate cancer and prostate cancer recurrence

J. Witte, P. Carroll, J. Chan, 2015, The Prostate.

Diet and premenopausal bilateral breast cancer: A case-control study

J. Witte, W. Thompson, J. Siemiatycki, 1997, Breast Cancer Research and Treatment.

The health effects of swimming in ocean water contaminated by storm drain runoff.

J S Witte, R C Millikan, J. Witte, 1999, Epidemiology.

Antioxidant and vitamin E transport genes and risk of high‐grade prostate cancer and prostate cancer recurrence

J. Witte, V. Weinberg, J. Chan, 2013, The Prostate.

Impact of Consumption of Vegetable, Fruit, Grain, and High Glycemic Index Foods on Aggressive Prostate Cancer Risk

J. Witte, I. Cheng, J. Hardin, 2011, Nutrition and cancer.

Androgen receptor CAG repeats and prostate cancer.

J. Witte, K. Nelson, 2002, American journal of epidemiology.

A nested approach to evaluating dose-response and trend.

J. Witte, S. Greenland, 1997, Annals of epidemiology.

Role of Androgen Metabolism Genes CYP 1 B 1 , PSA / KLK 3 , and CYP 11 a in Prostate Cancer Risk and Aggressiveness

J. Witte, G. Casey, M. Cicek, 2005 .

Polygenic modeling of genome-wide association studies: an application to prostate and breast cancer.

J. Witte, T. Hoffmann, 2011, Omics : a journal of integrative biology.

Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology

Scott M. Williams, J. Witte, E. Feuer, 2017, PLoS genetics.

Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas

J. Witte, Y. Kamatani, M. Lee, 2021, Diabetes Care.

Genome-Wide Meta-Analysis Identifies the Organic Anion-Transporting Polypeptide Gene SLCO1B1 and Statins as Modifiers of Glycemic Response to Sulfonylureas

J. Witte, Y. Kamatani, M. Lee, 2021 .

Association between inflammatory bowel disease and prostate cancer: A large‐scale, prospective, population‐based study

J. Witte, W. Catalona, E. Schaeffer, 2020, International journal of cancer.

Association between inflammatory bowel disease and prostate cancer: A large‐scale, prospective, population‐based study

J. Witte, W. Catalona, E. Schaeffer, 2020, International journal of cancer.

Testing Allele Transmission of an SNP Set Using a Family‐Based Generalized Genetic Random Field Method

J. Witte, M. Cleves, Q. Lu, 2016, Genetic epidemiology.

Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry

Gary K. Chen, Cameron D. Palmer, J. Witte, 2011, PLoS genetics.

BRIEF REPORTS Open Access

J. Witte, T. Hoffmann, K. S. Kompass, 2011 .

Polymorphisms in Polycyclic Aromatic Hydrocarbon Metabolism and Conjugation Genes, Interactions with Smoking and Prostate Cancer Risk

J. Witte, G. Casey, N. Nock, 2006, Cancer Epidemiology Biomarkers & Prevention.

The Association Between Cancer and Spousal Rate of Memory Decline

J. Witte, M. Glymour, K. Lu, 2020, Alzheimer Disease and Associated Disorders.

Genetic mapping of complex traits.

R C Elston, J S Witte, J M Olson, 1999, Statistics in medicine.

A machine learning approach to optimizing cell-free DNA sequencing panels: with an application to prostate cancer

J. Witte, P. Carroll, Clinton L. Cario, 2020, bioRxiv.

Re-envisioning community genetics: community empowerment in preventive genomics

J. Witte, E. Ashley, Jackie Osborne, 2023, Journal of Community Genetics.

A genome screen of multiplex sibships with prostate cancer.

J. Witte, J. Weber, R. Elston, 2000, American journal of human genetics.

Parallel biocomputing

John S. Witte, Kenneth S. Kompass, Thomas J. Hoffmann, 2011, Source Code for Biology and Medicine.

Genetic Variants in Transcription Factors Are Associated With the Pharmacokinetics and Pharmacodynamics of Metformin

J. Mefford, J. Witte, D. Roden, 2014, Clinical pharmacology and therapeutics.

Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk

J. Witte, S. Rasmussen, M. Gallagher, 2014, American Journal of Medical Genetics. Part A.

No Association between Genetic Polymorphisms in Insulin and Insulin Receptor Substrate-1 and Prostate Cancer

J. Witte, G. Casey, M. Cicek, 2005, Cancer Epidemiology Biomarkers & Prevention.

Genome‐wide association study and meta‐analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy

J. Witte, G. Koppelman, J. Hui, 2018, The Journal of allergy and clinical immunology.

Increased power for case‐control studies of single nucleotide polymorphisms through incorporation of family history and genetic constraints

J. Witte, D. Thompson, M. Slattery, 2004, Genetic epidemiology.

Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome

J. Witte, M. Matthay, E. Jorgenson, 2016, Critical Care.

Integration of polygenic risk scores with modifiable risk factors improves risk prediction: results from a pan-cancer analysis

J. Witte, E. Ziv, M. Johansson, 2020 .

CORRELATIONS OF INDIVIDUAL PLASMA CAROTENOID CONCENTRATIONS IN FREE-LIVING OLDER ADULTS

J. Witte, J. Shikany, 2000 .

The role of dementia diagnostic delay in the inverse cancer-dementia association.

J. Witte, M. Glymour, R. E. Graff, 2021, The journals of gerontology. Series A, Biological sciences and medical sciences.

A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma.

J. Witte, M. Nöthen, G. Koppelman, 2018, The Journal of allergy and clinical immunology.

Meat preparation and colorectal adenomas in a large sigmoidoscopy-based case-control study in California (United States)

J. Witte, R. Sinha, M. Longnecker, 1997, Cancer Causes & Control.

MIC1 and IL1RN Genetic Variation and Advanced Prostate Cancer Risk

J. Witte, G. Casey, I. Cheng, 2007, Cancer Epidemiology Biomarkers & Prevention.

Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma

J. Witte, J. Wiencke, J. Wiemels, 2017, Journal of Neuro-Oncology.

A Genome-Wide Association Study (GWAS) for Bronchopulmonary Dysplasia

J. Witte, G. Shaw, L. Lazzeroni, 2013, Pediatrics.

VALID: visualization of association study results and linkage disequilibrium

Mark Kvale, Eric Jorgenson, J. Witte, 2009, Genetic epidemiology.

Hypospadias and variants in genes related to sex hormone biosynthesis and metabolism

J. Witte, G. Shaw, S. Carmichael, 2014, Andrology.

Relation of Genes to Prostate Cancer Occurrence and Aggressiveness

J. Witte, 1999 .

Association between a CYP3A4Genetic Variant and Clinical Presentation in African-American Prostate Cancer Patients

J. Witte, G. Casey, E. Klein, 2000 .

Association between a CYP 3 A 4 Genetic Variant and Clinical Presentation in African-American Prostate Cancer Patients 1

J. Witte, H. Levin, G. Casey, 2000 .

Development and testing of a polygenic risk score for breast cancer aggressiveness

J. Witte, E. Ziv, L. Esserman, 2022, medRxiv.

Non-Steroidal Anti-Inflammatory Drugs, Variation in Inflammatory Genes, and Aggressive Prostate Cancer

J. Witte, G. Casey, I. Cheng, 2010, Pharmaceuticals.

Plasma ferritin, iron intake, and the risk of colorectal polyps.

C. L. Bird, J. Witte, M. Longnecker, 1996, American journal of epidemiology.

The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics

Megan L. Koleske, Swati S. More, J. Witte, 2023, bioRxiv.

Semiparametric Allelic Tests for Mapping Multiple Phenotypes: Binomial Regression and Mahalanobis Distance

J. Witte, Saurabh Ghosh, Arunabha Majumdar, 2015, Genetic epidemiology.

National Cancer Institute Prostate Cancer Genetics Workshop.

J. Witte, N. Camp, S. Chanock, 2011, Cancer research.

Opinion: A gene-centric approach to genome-wide association studies

John S Witte, Eric Jorgenson, J. Witte, 2006, Nature Reviews Genetics.

Copy number variation in bronchopulmonary dysplasia

J. Witte, J. Gould, C. Quaintance, 2014, American journal of medical genetics. Part A.

A complex systems model of breast cancer etiology: The Paradigm II Model

Ross A. Hammond, J. Witte, R. Hiatt, 2023, PloS one.

Microsatellite markers for genome-wide association studies

J. Witte, E. Jorgenson, 2007, Nature Reviews Genetics.

Prostate Cancer Susceptibility Variants Confer Increased Risk of Disease Progression

J. Witte, G. Casey, E. Klein, 2010, Cancer Epidemiology, Biomarkers & Prevention.

A Pharmacogenetic Prediction Model of Progression‐Free Survival in Breast Cancer using Genome‐Wide Genotyping Data from CALGB 40502 (Alliance)

Chen Jiang, Kouros Owzar, Katherina C. Chua, 2018, Clinical pharmacology and therapeutics.

Genetically adjusted PSA levels for prostate cancer screening

J. Witte, S. Chanock, P. Goodman, 2023, Nature Medicine.

Of Models and Methods

John S Witte, J. Witte, John S. Witte, 2011, Cancer Epidemiology, Biomarkers and Prevention.

Genetic analysis with hierarchical models

J S Witte, J. Witte, 1997, Genetic epidemiology.

HUMAN GENOME EPIDEMIOLOGY (HuGE) REVIEW Androgen Receptor CAG Repeats and Prostate Cancer

J. Witte, K. Nelson, 2002 .

A gene‐based association test of interactions for maternal–fetal genotypes identifies genes associated with nonsyndromic congenital heart defects

J. Witte, Nianjun Liu, W. Nembhard, 2023, Genetic epidemiology.

Imputed Genomic Data Reveals a Moderate Effect of Low Frequency Variants to the Heritability of Complex Human Traits

Ryan D. Hernandez, J. Witte, Kevin Hartman, 2019, bioRxiv.

Simulation study of hierarchical regression.

S Greenland, J S Witte, J. Witte, 1996, Statistics in medicine.

Introduction to Genetic Analysis Workshop 15 summaries

J. Witte, L. Almasy, R. Spielman, 2007, Genetic Epidemiology.

Introduction: Analysis of Sequence Data and Population Structure

J S Witte, B A Fijal, J. Witte, 2001, Genetic epidemiology.

Association of testis derived transcript gene variants and prostate cancer risk.

J. Witte, G. Casey, M. Cicek, 2007, The Journal of urology.

Monoclonal antibody therapy for resected Dukes' C colorectal cancer: seven-year outcome of a multicenter randomized trial.

J. Witte, W. Schmiegel, G. Schlimok, 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Haplotype Tagging Single Nucleotide Polymorphisms and Association Studies

John S. Witte, J. Witte, D. Stram, 2003, Human Heredity.

Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer

J. Witte, N. Risch, P. Kwok, 2017, Nature Communications.

Orchid: a novel management, annotation and machine learning framework for analyzing cancer mutations

John S. Witte, Clinton L. Cario, J. Witte, 2018, Bioinform..

Principles and methods for transferring polygenic risk scores across global populations

J. Witte, D. Schaid, N. Chatterjee, 2023, Nature reviews. Genetics.

Transmission of Mycobacterium tuberculosis from tuberculosis patients with HIV infection or AIDS.

J. Witte, K. Castro, I. Onorato, 1996, American journal of epidemiology.

Association within twin pairs for a dichotomous trait

J. Witte, R. Elston, J. Olson, 1996, Genetic epidemiology.

Transcriptome-Wide Association Analysis Identifies Novel Candidate Susceptibility Genes for Prostate-Specific Antigen Levels in Men Without Prostate Cancer

J. Witte, S. Chanock, D. Conti, 2023, medRxiv.

Epithelial tumor cells in bone marrow of patients with colorectal cancer: immunocytochemical detection, phenotypic characterization, and prognostic significance.

J. Witte, G. Schlimok, G. Riethmüller, 1990, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

No association between genetic polymorphisms in IGF-I and IGFBP-3 and prostate cancer.

Sexual practices in the transmission of hepatitis B virus and prevalence of hepatitis delta virus infection in female prostitutes in the United States.

J. Witte, S. Hadler, J. Potterat, 1992, JAMA.

Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms

John S Witte, Donglei Hu, Thomas J Hoffmann, 2019, Nature Communications.

Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry.

K. D. Sørensen, J. Witte, D. Schaid, 2023, American journal of human genetics.

Detecting methylation quantitative trait loci using a methylation random field method

John S Witte, Philip J Lupo, Benjamin Tycko, 2021, Briefings Bioinform..

Abstract PO-146: Multiethnic GWAS meta-analysis identifies novel variants and informs genetic risk prediction for prostate cancer across populations

Lilit C Moss, J. Witte, S. Chanock, 2020 .

Null Results in Brief MIC 1 and IL 1 RN Genetic Variation and Advanced Prostate Cancer Risk

J. Witte, G. Casey, I. Cheng, 2007 .

state Cancer Susceptibility Variants Confer Increased B & P of Disease Progression

J. Witte, G. Casey, E. Klein, 2010 .

Two Susceptibility Loci Identified for Prostate Cancer Aggressiveness

J. Witte, J. Carpten, H. Grönberg, 2015, Nature Communications.

Fine‐mapping of prostate cancer aggressiveness loci on chromosome 7q22–35

J. Witte, W. Catalona, B. Suarez, 2011, The Prostate.

Efficient Estimation and Applications of Cross-Validated Genetic Predictions to Polygenic Risk Scores and Linear Mixed Models

Jian Yang, Arthur Ko, Päivi Pajukanta, 2020, J. Comput. Biol..

Methodes de detection

J. Witte, D. Rank, G. Casey, 2003 .

Re: "Can energy adjustment separate the effects of energy from those of specific macronutrients?".

J. Witte, M. Pike, 1995, American journal of epidemiology.

Evaluating the performance of a genetic test using information from previous studies in place of a gold standard.

J S Witte, B A Fijal, J. Witte, 1998, Medical care.

Efficient estimation and applications of cross-validated genetic predictions

Danny S. Park, J. Mefford, J. Witte, 2019, bioRxiv.

Modeling age of onset and residual familial correlations for the linkage analysis of bipolar disorder

J. Witte, R. Elston, A. Schnell, 1997, Genetic Epidemiology.

Encapsulation Status of Papillary Thyroid Microcarcinomas is Associated with the Risk of Lymph Node Metastases and Tumor Multifocality

J. Witte, N. Lehwald, S. Baldus, 2013, Hormone and Metabolic Research.

Antioxidant and vitamin E transport genes and risk of high‐grade prostate cancer and prostate cancer recurrence

J. Witte, V. Weinberg, J. Chan, 2013, The Prostate.

The contribution of genetic variants to disease depends on the ruler

J. Witte, P. Visscher, N. Wray, 2014, Nature Reviews Genetics.

The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury.

J. Witte, E. Ziv, E. Vittinghoff, 2012, Chest.

Two HLA Class II Gene Variants Are Independently Associated with Pediatric Osteosarcoma Risk

J. Witte, I. Smirnov, H. Hansen, 2018, Cancer Epidemiology, Biomarkers & Prevention.

Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma

J. Witte, I. Smirnov, J. Wiencke, 2017, Journal of Neuro-Oncology.

Generalizability of established prostate cancer risk variants in men of African ancestry

J. Witte, J. Carpten, S. Chanock, 2015, International journal of cancer.

Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21

Gary K. Chen, J. Witte, M. Thun, 2011, Nature Genetics.

Impact of Consumption of Vegetable, Fruit, Grain, and High Glycemic Index Foods on Aggressive Prostate Cancer Risk

J. Witte, I. Cheng, J. Hardin, 2011, Nutrition and cancer.

New classification of chronic GVHD: added clarity from the consensus diagnoses

J. Witte, M. MacMillan, D. Weisdorf, 2009, Bone Marrow Transplantation.

Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry

K. D. Sørensen, J. Witte, D. Schaid, 2023, medRxiv.

ω–3 Fatty Acids, Genetic Variants in COX-2 and Prostate Cancer

J. Witte, V. Fradet, A. Reese, 2009, Lifestyle Genomics.

Association Between Alzheimer Disease and Cancer With Evaluation of Study Biases

J. Witte, R. E. Graff, L. Kobayashi, 2020, JAMA network open.

Two-stage approach for identifying single-nucleotide polymorphisms associated with rheumatoid arthritis using random forests and Bayesian networks

Qiong Yang, Anita L DeStefano, Kathryn L Lunetta, 2007, BMC proceedings.

Mutational Landscape of Aggressive Prostate Tumors in African American Men.

J. Mefford, J. Witte, W. Catalona, 2016, Cancer research.

A Meta-Analysis Identifies New Loci Associated with Body Mass index in Individuals of African Ancestry

Gary K. Chen, Scott M. Williams, Nicholette D. Palmer, 2013, Nature Genetics.

Validation of genome-wide prostate cancer associations in men of African descent.

J. Witte, S. Chanock, T. Rebbeck, 2011, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.